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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:288.1 nTPM
HPA Brain:282.8 nTPM
GTEx:288.1 nTPM
FANTOM5:655.8 Scaled Tags Per Million
Pig:213.3 nTPM
Mouse:209.5 nTPM
Allen mouse:3.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

282.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 254.0
2666 Male, age 74, left hemisphere 295.8
2586 Male, age 75, left hemisphere 289.9
2828 Female, age 72, unknown 256.1
1870 Female, age 42, unknown 254.2
1833 Male, age 53, unknown 244.5
2411 Female, age 72, unknown 243.0
1830 Male, age 51, unknown 241.4
2219 Male, age 76, both hemispheres 239.3
1827 Male, age 72, unknown 237.9
2019 Male, age 18, unknown 237.6
Dorsal raphe nucleus
nTPM: 242.6
2298 Female, age 72, unknown 247.6
2750 Male, age 76, both hemispheres 247.2
2016 Female, age 72, unknown 245.5
2047 Male, age 72, unknown 238.2
1828 Male, age 53, unknown 234.7
Inferior colliculus
nTPM: 236.0
1890 Male, age 53, unknown 255.6
1848 Female, age 42, unknown 241.5
2097 Female, age 72, unknown 224.9
2849 Male, age 72, unknown 222.1
Median raphe nucleus
nTPM: 259.8
2220 Male, age 76, midline 259.8
Periaquaductal grey, anterior
nTPM: 257.7
2502 Female, age 75, unknown 279.6
1947 Male, age 18, unknown 253.1
1795 Male, age 51, unknown 240.3
Periaquaductal grey, dorsal
nTPM: 218.4
1831 Male, age 72, unknown 235.2
1840 Male, age 53, unknown 229.3
2464 Female, age 72, unknown 213.1
2850 Male, age 76, both hemispheres 196.0
Periaquaductal grey, lateral
nTPM: 244.6
2272 Male, age 74, both hemispheres 279.6
2053 Male, age 18, unknown 249.5
2140 Male, age 76, both hemispheres 204.6
Pretectal area
nTPM: 231.3
2273 Male, age 74, both hemispheres 246.9
2224 Female, age 72, unknown 240.2
1815 Male, age 53, unknown 236.5
2407 Male, age 75, both hemispheres 235.9
1817 Female, age 42, unknown 233.4
1944 Female, age 72, unknown 232.2
2316 Male, age 76, right hemisphere 230.8
2007 Male, age 72, unknown 230.3
2825 Male, age 18, unknown 229.2
1816 Male, age 51, unknown 225.4
2667 Female, age 75, unknown 203.2
Red nucleus
nTPM: 253.1
2503 Female, age 72, unknown 306.7
1865 Male, age 51, unknown 281.1
1904 Male, age 53, unknown 272.3
2584 Male, age 75, left hemisphere 264.2
2785 Male, age 18, unknown 256.1
2769 Male, age 72, unknown 255.6
1821 Female, age 72, unknown 252.6
2227 Male, age 72, unknown 245.6
1954 Female, age 42, unknown 237.4
2823 Male, age 76, right hemisphere 226.6
2725 Female, age 75, unknown 223.4
2588 Male, age 74, left hemisphere 215.8
Substantia nigra
nTPM: 282.8
2665 Male, age 74, both hemispheres 314.6
2699 Male, age 18, unknown 314.6
1851 Male, age 51, unknown 310.3
1916 Female, age 42, unknown 304.9
2409 Female, age 72, unknown 287.1
2590 Female, age 75, unknown 282.8
2241 Male, age 72, unknown 269.1
1889 Female, age 72, unknown 257.0
2583 Male, age 75, right hemisphere 247.3
1941 Male, age 53, unknown 240.4
Superior colliculus
nTPM: 253.7
2668 Female, age 75, unknown 295.5
1995 Male, age 72, unknown 284.7
2587 Male, age 74, left hemisphere 277.7
1913 Female, age 42, unknown 273.9
2664 Male, age 75, both hemispheres 263.3
1796 Male, age 53, unknown 247.7
1839 Male, age 51, unknown 243.7
2261 Male, age 18, unknown 235.3
2087 Female, age 72, unknown 220.5
1895 Male, age 76, right hemisphere 194.8
Ventral tegmental area
nTPM: 269.2
1915 Female, age 42, unknown 280.6
2410 Female, age 72, unknown 276.6
2021 Male, age 53, unknown 271.5
2223 Female, age 72, unknown 266.0
2218 Male, age 76, both hemispheres 260.2
1942 Male, age 51, unknown 260.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

288.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 288.1
Samples: 139

Max nTPM: 645.8
Min nTPM: 141.5
Std nTPM: 80.0
Median nTPM: 270.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 645.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 554.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 509.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 490.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 487.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 460.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 448.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 432.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 431.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 422.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 405.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 401.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 396.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 382.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 381.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 373.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 372.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 372.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 364.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 364.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 364.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 361.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 360.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 359.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 359.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 356.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 353.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 344.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 342.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 342.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 341.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 338.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 337.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 337.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 336.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 328.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 327.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 325.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 324.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 321.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 317.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 316.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 309.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 309.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 305.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 304.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 303.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 303.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 300.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 294.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 291.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 291.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 291.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 290.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 288.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 286.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 281.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 279.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 278.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 278.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 276.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 275.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 275.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 274.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 274.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 273.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 272.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 272.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 271.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 270.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 270.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 267.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 267.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 267.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 267.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 267.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 262.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 262.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 261.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 258.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 256.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 256.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 255.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 254.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 253.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 253.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 252.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 252.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 251.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 251.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 249.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 247.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 244.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 243.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 243.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 243.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 243.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 242.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 242.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 238.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 237.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 234.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 233.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 231.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 231.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 230.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 229.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 228.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 225.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 224.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 222.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 221.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 220.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 219.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 219.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 218.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 216.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 216.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 214.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 211.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 210.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 209.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 209.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 208.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 206.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 206.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 206.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 203.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 202.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 200.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 195.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 192.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 191.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 189.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 187.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 184.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 184.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 178.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 141.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

655.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 655.8
FF:10158-103A5 76 years, female 655.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

213.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 199.2
Samples: 4

Max nTPM: 244.7
Min nTPM: 161.7
Sample A Female 244.7
Sample B Female 213.2
Sample C Male 177.2
Sample D Male 161.7
Midbrain
nTPM: 190.8
Samples: 4

Max nTPM: 262.0
Min nTPM: 146.7
Sample A Female 262.0
Sample B Female 188.4
Sample C Male 166.0
Sample D Male 146.7
Periaqueductal gray
nTPM: 165.0
Samples: 3

Max nTPM: 181.6
Min nTPM: 147.2
Sample B Female 166.3
Sample C Male 181.6
Sample D Male 147.2
Superior colliculi
nTPM: 213.3
Samples: 4

Max nTPM: 266.4
Min nTPM: 173.1
Sample A Female 234.9
Sample B Female 266.4
Sample C Male 173.1
Sample D Male 178.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

209.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 209.5
Samples: 4

Max nTPM: 234.3
Min nTPM: 186.1
Sample A Male 234.3
Sample B Male 197.5
Sample C Female 186.1
Sample D Female 220.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.6
71021172 Antisense, RP_050531_01_G07, Mouse strain C57BL/6J (56 days, male) 3.6

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