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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:98.2 nTPM
HPA Brain:215.3 nTPM
GTEx:98.2 nTPM
FANTOM5:206.5 Scaled Tags Per Million
Pig:129.4 nTPM
Mouse:97.6 nTPM
Allen mouse:6.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

215.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 204.3
2586 Male, age 75, left hemisphere 257.4
2666 Male, age 74, left hemisphere 248.7
2019 Male, age 18, unknown 244.3
1827 Male, age 72, unknown 205.5
2411 Female, age 72, unknown 192.8
2828 Female, age 72, unknown 191.3
2219 Male, age 76, both hemispheres 186.0
1830 Male, age 51, unknown 173.6
1870 Female, age 42, unknown 172.1
1833 Male, age 53, unknown 171.3
Dorsal raphe nucleus
nTPM: 161.9
2750 Male, age 76, both hemispheres 187.5
2047 Male, age 72, unknown 171.6
2298 Female, age 72, unknown 167.4
1828 Male, age 53, unknown 162.9
2016 Female, age 72, unknown 119.9
Inferior colliculus
nTPM: 160.5
1890 Male, age 53, unknown 170.2
2097 Female, age 72, unknown 167.6
2849 Male, age 72, unknown 152.2
1848 Female, age 42, unknown 152.0
Median raphe nucleus
nTPM: 173.2
2220 Male, age 76, midline 173.2
Periaquaductal grey, anterior
nTPM: 189.1
2502 Female, age 75, unknown 211.3
1795 Male, age 51, unknown 189.0
1947 Male, age 18, unknown 167.0
Periaquaductal grey, dorsal
nTPM: 141.1
1831 Male, age 72, unknown 158.9
2464 Female, age 72, unknown 155.4
1840 Male, age 53, unknown 131.0
2850 Male, age 76, both hemispheres 119.2
Periaquaductal grey, lateral
nTPM: 133.8
2053 Male, age 18, unknown 148.5
2272 Male, age 74, both hemispheres 138.5
2140 Male, age 76, both hemispheres 114.6
Pretectal area
nTPM: 215.3
1816 Male, age 51, unknown 313.1
2007 Male, age 72, unknown 298.2
1817 Female, age 42, unknown 288.0
1944 Female, age 72, unknown 280.5
1815 Male, age 53, unknown 256.6
2407 Male, age 75, both hemispheres 186.9
2667 Female, age 75, unknown 163.5
2825 Male, age 18, unknown 149.6
2224 Female, age 72, unknown 147.7
2316 Male, age 76, right hemisphere 145.2
2273 Male, age 74, both hemispheres 138.8
Red nucleus
nTPM: 207.5
2588 Male, age 74, left hemisphere 247.6
2785 Male, age 18, unknown 245.2
2584 Male, age 75, left hemisphere 236.8
2725 Female, age 75, unknown 211.5
1865 Male, age 51, unknown 208.4
2503 Female, age 72, unknown 207.4
2823 Male, age 76, right hemisphere 200.1
1904 Male, age 53, unknown 193.1
1821 Female, age 72, unknown 192.1
1954 Female, age 42, unknown 185.5
2769 Male, age 72, unknown 181.9
2227 Male, age 72, unknown 180.8
Substantia nigra
nTPM: 205.0
1889 Female, age 72, unknown 249.1
1941 Male, age 53, unknown 240.0
1916 Female, age 42, unknown 232.3
1851 Male, age 51, unknown 210.2
2665 Male, age 74, both hemispheres 207.5
2583 Male, age 75, right hemisphere 198.8
2409 Female, age 72, unknown 186.8
2590 Female, age 75, unknown 185.0
2241 Male, age 72, unknown 172.3
2699 Male, age 18, unknown 167.8
Superior colliculus
nTPM: 200.3
2087 Female, age 72, unknown 251.4
2668 Female, age 75, unknown 237.1
2261 Male, age 18, unknown 230.8
1796 Male, age 53, unknown 201.0
1913 Female, age 42, unknown 193.7
2664 Male, age 75, both hemispheres 188.9
2587 Male, age 74, left hemisphere 182.0
1895 Male, age 76, right hemisphere 178.5
1995 Male, age 72, unknown 177.1
1839 Male, age 51, unknown 162.1
Ventral tegmental area
nTPM: 180.1
2410 Female, age 72, unknown 216.4
2218 Male, age 76, both hemispheres 194.1
1915 Female, age 42, unknown 184.7
2223 Female, age 72, unknown 178.2
1942 Male, age 51, unknown 158.5
2021 Male, age 53, unknown 148.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

98.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 98.2
Samples: 139

Max nTPM: 262.1
Min nTPM: 45.7
Std nTPM: 28.7
Median nTPM: 92.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 262.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 198.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 164.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 160.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 152.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 151.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 147.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 143.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 139.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 139.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 137.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 135.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 132.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 132.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 131.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 131.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 128.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 125.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 124.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 123.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 123.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 123.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 121.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 120.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 120.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 119.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 119.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 118.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 118.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 118.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 117.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 117.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 116.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 115.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 114.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 114.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 113.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 112.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 110.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 110.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 108.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 108.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 108.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 107.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 106.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 105.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 104.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 104.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 103.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 103.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 103.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 102.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 101.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 100.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 100.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 100.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 99.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 99.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 98.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 98.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 97.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 97.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 96.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 96.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 95.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 94.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 93.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 93.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 92.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 92.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 92.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 91.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 91.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 91.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 91.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 91.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 90.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 90.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 89.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 88.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 88.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 88.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 87.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 86.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 85.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 83.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 83.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 83.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 83.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 83.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 82.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 82.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 81.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 81.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 80.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 80.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 80.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 79.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 79.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 79.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 79.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 78.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 78.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 78.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 78.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 78.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 77.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 77.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 77.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 77.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 76.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 76.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 76.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 75.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 75.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 75.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 74.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 74.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 74.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 73.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 73.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 72.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 71.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 71.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 71.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 71.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 70.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 69.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 65.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 65.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 64.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 64.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 62.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 60.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 59.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 59.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 58.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 47.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 45.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

206.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 206.5
FF:10158-103A5 76 years, female 206.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

129.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 116.5
Samples: 4

Max nTPM: 149.5
Min nTPM: 87.7
Sample A Female 140.5
Sample B Female 87.7
Sample C Male 149.5
Sample D Male 88.3
Midbrain
nTPM: 125.6
Samples: 4

Max nTPM: 152.7
Min nTPM: 95.7
Sample A Female 122.3
Sample B Female 95.7
Sample C Male 152.7
Sample D Male 131.8
Periaqueductal gray
nTPM: 98.0
Samples: 3

Max nTPM: 116.2
Min nTPM: 85.0
Sample B Female 92.8
Sample C Male 116.2
Sample D Male 85.0
Superior colliculi
nTPM: 129.4
Samples: 4

Max nTPM: 158.7
Min nTPM: 88.6
Sample A Female 134.6
Sample B Female 88.6
Sample C Male 158.7
Sample D Male 135.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

97.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 97.6
Samples: 4

Max nTPM: 104.1
Min nTPM: 88.3
Sample A Male 104.1
Sample B Male 88.3
Sample C Female 97.1
Sample D Female 100.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

6.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.2
70946413 Antisense, RP_050428_01_B04, Mouse strain C57BL/6J (56 days, male) 12.3
70795466 Antisense, RP_050712_01_F05, Mouse strain C57BL/6J (56 days, male) 0.0

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