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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:317.9 nTPM
HPA Brain:402.7 nTPM
GTEx:317.9 nTPM
FANTOM5:459.3 Scaled Tags Per Million
Pig:579.9 nTPM
Mouse:203.2 nTPM
Allen mouse:1.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

402.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 226.4
2019 Male, age 18, unknown 260.7
2411 Female, age 72, unknown 259.2
2828 Female, age 72, unknown 257.6
1870 Female, age 42, unknown 251.6
1827 Male, age 72, unknown 230.2
2219 Male, age 76, both hemispheres 226.5
1830 Male, age 51, unknown 208.3
1833 Male, age 53, unknown 207.6
2586 Male, age 75, left hemisphere 198.7
2666 Male, age 74, left hemisphere 163.9
Dorsal raphe nucleus
nTPM: 292.4
2298 Female, age 72, unknown 413.0
2750 Male, age 76, both hemispheres 313.5
2047 Male, age 72, unknown 299.2
1828 Male, age 53, unknown 240.1
2016 Female, age 72, unknown 196.2
Inferior colliculus
nTPM: 260.0
2097 Female, age 72, unknown 344.8
1890 Male, age 53, unknown 261.8
1848 Female, age 42, unknown 229.7
2849 Male, age 72, unknown 203.8
Median raphe nucleus
nTPM: 402.7
2220 Male, age 76, midline 402.7
Periaquaductal grey, anterior
nTPM: 357.6
1795 Male, age 51, unknown 394.6
1947 Male, age 18, unknown 351.1
2502 Female, age 75, unknown 327.1
Periaquaductal grey, dorsal
nTPM: 225.2
2850 Male, age 76, both hemispheres 254.3
1840 Male, age 53, unknown 239.5
1831 Male, age 72, unknown 206.9
2464 Female, age 72, unknown 200.1
Periaquaductal grey, lateral
nTPM: 288.7
2272 Male, age 74, both hemispheres 377.2
2140 Male, age 76, both hemispheres 262.0
2053 Male, age 18, unknown 226.9
Pretectal area
nTPM: 297.3
2007 Male, age 72, unknown 361.5
1817 Female, age 42, unknown 351.0
2224 Female, age 72, unknown 349.6
2273 Male, age 74, both hemispheres 343.9
1816 Male, age 51, unknown 342.7
1944 Female, age 72, unknown 308.9
2667 Female, age 75, unknown 269.2
1815 Male, age 53, unknown 269.0
2825 Male, age 18, unknown 235.1
2316 Male, age 76, right hemisphere 225.5
2407 Male, age 75, both hemispheres 213.6
Red nucleus
nTPM: 260.8
2785 Male, age 18, unknown 325.8
2769 Male, age 72, unknown 302.7
2227 Male, age 72, unknown 301.6
2725 Female, age 75, unknown 297.1
2584 Male, age 75, left hemisphere 280.5
2503 Female, age 72, unknown 276.5
1821 Female, age 72, unknown 262.2
1865 Male, age 51, unknown 244.0
1904 Male, age 53, unknown 230.1
1954 Female, age 42, unknown 227.8
2823 Male, age 76, right hemisphere 225.1
2588 Male, age 74, left hemisphere 156.1
Substantia nigra
nTPM: 249.8
1916 Female, age 42, unknown 350.7
1889 Female, age 72, unknown 297.6
1941 Male, age 53, unknown 279.0
1851 Male, age 51, unknown 275.9
2583 Male, age 75, right hemisphere 247.0
2590 Female, age 75, unknown 243.5
2665 Male, age 74, both hemispheres 205.9
2241 Male, age 72, unknown 204.3
2409 Female, age 72, unknown 201.5
2699 Male, age 18, unknown 192.9
Superior colliculus
nTPM: 248.9
1796 Male, age 53, unknown 347.3
2261 Male, age 18, unknown 327.2
2087 Female, age 72, unknown 298.2
2587 Male, age 74, left hemisphere 251.9
1913 Female, age 42, unknown 251.6
2668 Female, age 75, unknown 249.2
1995 Male, age 72, unknown 211.5
1839 Male, age 51, unknown 205.5
1895 Male, age 76, right hemisphere 186.7
2664 Male, age 75, both hemispheres 159.9
Ventral tegmental area
nTPM: 323.3
2223 Female, age 72, unknown 449.5
2218 Male, age 76, both hemispheres 357.8
1942 Male, age 51, unknown 290.6
1915 Female, age 42, unknown 286.0
2410 Female, age 72, unknown 281.9
2021 Male, age 53, unknown 274.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

317.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 317.9
Samples: 139

Max nTPM: 706.1
Min nTPM: 112.0
Std nTPM: 85.0
Median nTPM: 313.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 706.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 556.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 513.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 481.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 477.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 474.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 469.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 462.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 448.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 442.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 441.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 439.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 435.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 435.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 432.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 406.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 402.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 402.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 398.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 392.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 392.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 390.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 387.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 380.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 378.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 375.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 374.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 374.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 374.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 373.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 373.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 371.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 367.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 366.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 365.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 365.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 363.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 362.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 360.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 360.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 357.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 353.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 351.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 349.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 349.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 348.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 346.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 346.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 345.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 345.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 342.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 341.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 340.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 338.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 337.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 333.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 331.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 330.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 325.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 325.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 324.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 322.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 322.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 321.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 320.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 317.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 314.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 314.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 314.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 313.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 311.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 311.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 310.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 308.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 307.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 302.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 302.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 301.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 300.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 298.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 297.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 297.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 294.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 294.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 293.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 293.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 288.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 287.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 286.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 285.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 282.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 282.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 282.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 281.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 281.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 279.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 277.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 273.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 271.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 271.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 270.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 269.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 264.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 263.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 262.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 260.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 259.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 254.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 252.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 251.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 246.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 245.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 245.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 243.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 241.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 238.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 237.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 235.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 233.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 233.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 231.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 230.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 228.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 228.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 225.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 224.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 222.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 219.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 219.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 216.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 208.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 191.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 181.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 172.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 171.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 148.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 148.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 142.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 112.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

459.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 459.3
FF:10158-103A5 76 years, female 459.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

579.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 477.4
Samples: 4

Max nTPM: 692.4
Min nTPM: 262.3
Sample A Female 692.4
Sample B Female 401.0
Sample C Male 553.8
Sample D Male 262.3
Midbrain
nTPM: 522.2
Samples: 4

Max nTPM: 673.9
Min nTPM: 424.8
Sample A Female 484.7
Sample B Female 424.8
Sample C Male 673.9
Sample D Male 505.5
Periaqueductal gray
nTPM: 396.1
Samples: 3

Max nTPM: 494.4
Min nTPM: 345.7
Sample B Female 345.7
Sample C Male 494.4
Sample D Male 348.2
Superior colliculi
nTPM: 580.0
Samples: 4

Max nTPM: 713.6
Min nTPM: 461.5
Sample A Female 713.6
Sample B Female 480.9
Sample C Male 663.8
Sample D Male 461.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

203.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 203.2
Samples: 4

Max nTPM: 272.4
Min nTPM: 158.2
Sample A Male 272.4
Sample B Male 177.0
Sample C Female 158.2
Sample D Female 205.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.6
2407 Antisense, RP_Baylor_102906, Mouse strain C57BL/6J (56 days, male) 1.6
2408 Antisense, RP_Baylor_102906, Mouse strain C57BL/6J (56 days, male) 0.7

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