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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:525.2 nTPM
HPA Brain:224.6 nTPM
GTEx:525.2 nTPM
FANTOM5:86.3 Scaled Tags Per Million
Pig:91.9 nTPM
Mouse:266.0 nTPM
Allen mouse:1.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

224.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 172.0
2019 Male, age 18, unknown 199.1
1827 Male, age 72, unknown 195.4
2219 Male, age 76, both hemispheres 176.6
2828 Female, age 72, unknown 175.2
1870 Female, age 42, unknown 173.5
2586 Male, age 75, left hemisphere 171.9
1833 Male, age 53, unknown 160.3
2666 Male, age 74, left hemisphere 157.9
1830 Male, age 51, unknown 155.5
2411 Female, age 72, unknown 154.2
Dorsal raphe nucleus
nTPM: 185.7
2298 Female, age 72, unknown 210.6
1828 Male, age 53, unknown 210.0
2047 Male, age 72, unknown 193.6
2750 Male, age 76, both hemispheres 169.7
2016 Female, age 72, unknown 144.6
Inferior colliculus
nTPM: 190.9
2097 Female, age 72, unknown 199.6
1890 Male, age 53, unknown 195.9
1848 Female, age 42, unknown 191.1
2849 Male, age 72, unknown 177.1
Median raphe nucleus
nTPM: 196.2
2220 Male, age 76, midline 196.2
Periaquaductal grey, anterior
nTPM: 184.8
1947 Male, age 18, unknown 198.6
1795 Male, age 51, unknown 197.2
2502 Female, age 75, unknown 158.6
Periaquaductal grey, dorsal
nTPM: 170.7
2850 Male, age 76, both hemispheres 210.4
1840 Male, age 53, unknown 165.5
1831 Male, age 72, unknown 154.8
2464 Female, age 72, unknown 152.1
Periaquaductal grey, lateral
nTPM: 174.7
2272 Male, age 74, both hemispheres 187.5
2053 Male, age 18, unknown 179.4
2140 Male, age 76, both hemispheres 157.0
Pretectal area
nTPM: 224.6
1817 Female, age 42, unknown 286.2
1816 Male, age 51, unknown 275.3
2007 Male, age 72, unknown 273.3
2667 Female, age 75, unknown 257.7
1944 Female, age 72, unknown 254.3
1815 Male, age 53, unknown 230.9
2224 Female, age 72, unknown 204.1
2273 Male, age 74, both hemispheres 187.9
2407 Male, age 75, both hemispheres 176.8
2825 Male, age 18, unknown 172.4
2316 Male, age 76, right hemisphere 151.6
Red nucleus
nTPM: 181.6
1821 Female, age 72, unknown 256.2
2725 Female, age 75, unknown 213.5
2823 Male, age 76, right hemisphere 204.3
2503 Female, age 72, unknown 187.2
2785 Male, age 18, unknown 184.5
1865 Male, age 51, unknown 174.2
2227 Male, age 72, unknown 170.2
1954 Female, age 42, unknown 167.1
2769 Male, age 72, unknown 166.7
1904 Male, age 53, unknown 156.6
2584 Male, age 75, left hemisphere 149.9
2588 Male, age 74, left hemisphere 148.1
Substantia nigra
nTPM: 211.8
1916 Female, age 42, unknown 274.0
1889 Female, age 72, unknown 244.0
1851 Male, age 51, unknown 227.1
1941 Male, age 53, unknown 218.8
2409 Female, age 72, unknown 214.6
2241 Male, age 72, unknown 212.0
2665 Male, age 74, both hemispheres 209.5
2699 Male, age 18, unknown 200.2
2590 Female, age 75, unknown 164.1
2583 Male, age 75, right hemisphere 153.3
Superior colliculus
nTPM: 183.9
2587 Male, age 74, left hemisphere 216.6
2087 Female, age 72, unknown 207.1
1796 Male, age 53, unknown 200.1
2668 Female, age 75, unknown 193.4
1895 Male, age 76, right hemisphere 192.0
2261 Male, age 18, unknown 182.9
1839 Male, age 51, unknown 172.2
1913 Female, age 42, unknown 163.5
1995 Male, age 72, unknown 161.0
2664 Male, age 75, both hemispheres 150.6
Ventral tegmental area
nTPM: 190.9
2218 Male, age 76, both hemispheres 224.9
1915 Female, age 42, unknown 213.4
2410 Female, age 72, unknown 201.1
2223 Female, age 72, unknown 182.4
2021 Male, age 53, unknown 167.7
1942 Male, age 51, unknown 156.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

525.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 525.2
Samples: 139

Max nTPM: 932.0
Min nTPM: 226.4
Std nTPM: 135.3
Median nTPM: 505.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 932.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 920.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 879.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 851.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 825.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 811.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 792.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 792.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 779.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 774.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 746.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 740.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 727.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 708.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 702.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 699.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 695.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 695.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 686.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 669.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 662.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 651.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 649.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 641.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 637.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 636.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 629.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 629.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 627.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 613.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 613.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 612.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 603.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 602.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 597.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 596.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 588.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 584.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 582.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 576.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 576.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 571.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 570.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 570.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 563.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 559.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 557.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 555.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 554.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 550.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 550.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 549.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 547.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 546.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 542.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 538.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 536.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 536.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 533.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 530.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 521.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 520.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 516.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 510.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 509.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 508.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 508.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 507.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 507.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 505.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 505.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 504.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 503.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 501.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 497.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 497.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 492.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 490.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 488.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 488.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 482.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 481.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 480.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 475.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 474.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 473.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 473.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 473.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 471.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 470.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 470.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 469.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 464.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 462.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 461.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 461.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 451.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 449.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 446.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 444.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 436.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 434.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 433.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 429.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 428.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 425.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 421.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 418.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 417.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 413.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 412.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 410.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 409.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 409.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 409.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 406.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 405.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 402.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 400.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 396.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 395.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 390.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 389.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 387.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 383.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 380.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 374.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 351.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 350.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 346.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 343.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 337.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 327.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 321.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 316.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 289.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 287.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 251.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 226.4
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

86.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 86.3
FF:10158-103A5 76 years, female 86.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

91.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 77.3
Samples: 4

Max nTPM: 107.4
Min nTPM: 47.6
Sample A Female 107.4
Sample B Female 69.7
Sample C Male 84.5
Sample D Male 47.6
Midbrain
nTPM: 84.1
Samples: 4

Max nTPM: 93.1
Min nTPM: 70.2
Sample A Female 90.0
Sample B Female 70.2
Sample C Male 93.1
Sample D Male 83.2
Periaqueductal gray
nTPM: 64.6
Samples: 3

Max nTPM: 78.6
Min nTPM: 51.9
Sample B Female 63.2
Sample C Male 78.6
Sample D Male 51.9
Superior colliculi
nTPM: 92.0
Samples: 4

Max nTPM: 126.2
Min nTPM: 66.0
Sample A Female 126.2
Sample B Female 66.0
Sample C Male 101.0
Sample D Male 74.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

266.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 266.0
Samples: 4

Max nTPM: 294.7
Min nTPM: 238.5
Sample A Male 294.7
Sample B Male 247.2
Sample C Female 238.5
Sample D Female 283.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.7
75198094 Antisense, RP_060502_01_F10, Mouse strain C57BL/6J (56 days, male) 1.7

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