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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:334.4 nTPM
HPA Brain:168.8 nTPM
GTEx:334.4 nTPM
FANTOM5:138.4 Scaled Tags Per Million
Pig:150.5 nTPM
Mouse:137.0 nTPM
Allen mouse:4.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

168.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 134.5
2019 Male, age 18, unknown 172.0
2586 Male, age 75, left hemisphere 158.7
2666 Male, age 74, left hemisphere 154.6
1827 Male, age 72, unknown 135.6
2828 Female, age 72, unknown 134.5
2411 Female, age 72, unknown 130.4
1870 Female, age 42, unknown 129.9
1833 Male, age 53, unknown 113.1
2219 Male, age 76, both hemispheres 109.6
1830 Male, age 51, unknown 107.0
Dorsal raphe nucleus
nTPM: 155.0
2047 Male, age 72, unknown 187.5
2298 Female, age 72, unknown 171.5
1828 Male, age 53, unknown 156.4
2750 Male, age 76, both hemispheres 146.3
2016 Female, age 72, unknown 113.2
Inferior colliculus
nTPM: 127.7
1890 Male, age 53, unknown 149.3
2097 Female, age 72, unknown 144.6
1848 Female, age 42, unknown 112.6
2849 Male, age 72, unknown 104.1
Median raphe nucleus
nTPM: 151.7
2220 Male, age 76, midline 151.7
Periaquaductal grey, anterior
nTPM: 146.4
1947 Male, age 18, unknown 148.9
1795 Male, age 51, unknown 148.3
2502 Female, age 75, unknown 142.1
Periaquaductal grey, dorsal
nTPM: 111.7
2850 Male, age 76, both hemispheres 116.0
1831 Male, age 72, unknown 113.2
2464 Female, age 72, unknown 109.1
1840 Male, age 53, unknown 108.4
Periaquaductal grey, lateral
nTPM: 109.4
2272 Male, age 74, both hemispheres 123.4
2053 Male, age 18, unknown 104.8
2140 Male, age 76, both hemispheres 100.0
Pretectal area
nTPM: 136.8
2007 Male, age 72, unknown 175.1
1817 Female, age 42, unknown 171.5
1816 Male, age 51, unknown 168.2
1944 Female, age 72, unknown 167.1
1815 Male, age 53, unknown 142.8
2667 Female, age 75, unknown 132.4
2273 Male, age 74, both hemispheres 115.4
2407 Male, age 75, both hemispheres 109.6
2825 Male, age 18, unknown 109.0
2316 Male, age 76, right hemisphere 107.2
2224 Female, age 72, unknown 107.1
Red nucleus
nTPM: 144.8
1821 Female, age 72, unknown 177.4
2503 Female, age 72, unknown 171.5
2725 Female, age 75, unknown 163.6
2785 Male, age 18, unknown 152.6
1865 Male, age 51, unknown 149.0
2588 Male, age 74, left hemisphere 137.3
1904 Male, age 53, unknown 134.9
2769 Male, age 72, unknown 132.8
2584 Male, age 75, left hemisphere 132.4
2227 Male, age 72, unknown 131.8
2823 Male, age 76, right hemisphere 130.0
1954 Female, age 42, unknown 124.3
Substantia nigra
nTPM: 168.8
1916 Female, age 42, unknown 217.8
1851 Male, age 51, unknown 208.0
1889 Female, age 72, unknown 176.8
1941 Male, age 53, unknown 174.2
2665 Male, age 74, both hemispheres 173.8
2241 Male, age 72, unknown 167.8
2699 Male, age 18, unknown 147.4
2590 Female, age 75, unknown 147.0
2409 Female, age 72, unknown 142.5
2583 Male, age 75, right hemisphere 132.7
Superior colliculus
nTPM: 126.0
2087 Female, age 72, unknown 147.0
2587 Male, age 74, left hemisphere 143.0
1796 Male, age 53, unknown 141.3
2668 Female, age 75, unknown 130.4
2261 Male, age 18, unknown 129.8
2664 Male, age 75, both hemispheres 128.3
1913 Female, age 42, unknown 115.3
1895 Male, age 76, right hemisphere 110.3
1995 Male, age 72, unknown 107.5
1839 Male, age 51, unknown 106.9
Ventral tegmental area
nTPM: 146.9
1915 Female, age 42, unknown 177.5
2410 Female, age 72, unknown 157.3
2218 Male, age 76, both hemispheres 147.5
2223 Female, age 72, unknown 145.8
1942 Male, age 51, unknown 129.2
2021 Male, age 53, unknown 123.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

334.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 334.4
Samples: 139

Max nTPM: 670.8
Min nTPM: 171.8
Std nTPM: 83.0
Median nTPM: 325.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 670.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 626.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 615.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 533.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 514.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 495.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 482.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 476.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 472.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 467.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 450.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 444.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 443.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 431.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 431.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 428.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 424.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 419.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 417.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 411.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 411.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 410.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 406.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 404.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 401.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 398.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 395.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 390.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 385.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 384.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 382.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 380.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 376.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 374.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 373.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 372.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 363.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 360.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 360.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 359.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 358.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 357.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 355.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 354.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 351.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 349.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 347.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 346.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 345.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 345.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 344.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 344.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 343.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 343.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 343.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 343.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 339.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 336.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 333.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 330.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 329.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 329.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 329.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 328.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 328.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 326.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 326.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 326.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 325.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 325.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 323.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 322.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 322.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 321.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 320.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 320.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 319.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 318.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 317.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 316.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 316.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 315.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 315.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 314.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 313.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 310.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 309.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 306.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 304.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 303.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 303.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 303.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 302.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 302.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 299.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 298.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 296.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 294.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 291.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 290.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 286.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 285.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 284.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 284.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 280.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 279.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 279.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 275.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 275.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 274.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 272.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 269.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 266.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 266.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 260.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 260.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 257.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 256.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 255.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 252.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 252.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 250.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 250.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 242.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 240.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 239.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 238.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 232.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 226.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 226.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 225.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 220.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 218.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 215.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 205.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 194.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 187.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 183.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 171.8
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

138.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 138.4
FF:10158-103A5 76 years, female 138.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

150.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 150.5
Samples: 4

Max nTPM: 225.0
Min nTPM: 97.0
Sample A Female 225.0
Sample B Female 136.5
Sample C Male 143.4
Sample D Male 97.0
Midbrain
nTPM: 132.4
Samples: 4

Max nTPM: 164.9
Min nTPM: 113.0
Sample A Female 164.9
Sample B Female 137.7
Sample C Male 113.0
Sample D Male 113.9
Periaqueductal gray
nTPM: 106.8
Samples: 3

Max nTPM: 120.6
Min nTPM: 90.0
Sample B Female 109.7
Sample C Male 120.6
Sample D Male 90.0
Superior colliculi
nTPM: 134.0
Samples: 4

Max nTPM: 191.0
Min nTPM: 106.5
Sample A Female 191.0
Sample B Female 126.3
Sample C Male 112.1
Sample D Male 106.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

137.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 137.1
Samples: 4

Max nTPM: 151.5
Min nTPM: 123.5
Sample A Male 149.0
Sample B Male 124.2
Sample C Female 123.5
Sample D Female 151.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.6
69782276 Antisense, RP_050505_02_F07, Mouse strain C57BL/6J (56 days, male) 4.6

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