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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:704.1 nTPM
HPA Brain:390.7 nTPM
GTEx:704.1 nTPM
FANTOM5:17.2 Scaled Tags Per Million
Pig:320.0 nTPM
Mouse:345.3 nTPM
Allen mouse:14.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

390.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 327.4
2586 Male, age 75, left hemisphere 388.9
2666 Male, age 74, left hemisphere 369.2
1870 Female, age 42, unknown 366.7
2411 Female, age 72, unknown 321.2
2828 Female, age 72, unknown 321.1
1833 Male, age 53, unknown 317.5
1827 Male, age 72, unknown 307.3
1830 Male, age 51, unknown 303.4
2219 Male, age 76, both hemispheres 295.4
2019 Male, age 18, unknown 283.4
Dorsal raphe nucleus
nTPM: 373.2
2298 Female, age 72, unknown 403.7
2016 Female, age 72, unknown 394.2
2047 Male, age 72, unknown 377.8
1828 Male, age 53, unknown 370.8
2750 Male, age 76, both hemispheres 319.7
Inferior colliculus
nTPM: 338.4
1848 Female, age 42, unknown 347.3
2849 Male, age 72, unknown 346.9
1890 Male, age 53, unknown 339.7
2097 Female, age 72, unknown 319.5
Median raphe nucleus
nTPM: 333.7
2220 Male, age 76, midline 333.7
Periaquaductal grey, anterior
nTPM: 323.5
2502 Female, age 75, unknown 348.2
1947 Male, age 18, unknown 315.8
1795 Male, age 51, unknown 306.6
Periaquaductal grey, dorsal
nTPM: 337.8
1840 Male, age 53, unknown 404.4
1831 Male, age 72, unknown 330.0
2850 Male, age 76, both hemispheres 310.6
2464 Female, age 72, unknown 306.4
Periaquaductal grey, lateral
nTPM: 314.9
2053 Male, age 18, unknown 352.8
2140 Male, age 76, both hemispheres 312.5
2272 Male, age 74, both hemispheres 279.5
Pretectal area
nTPM: 292.6
2825 Male, age 18, unknown 353.3
2224 Female, age 72, unknown 343.3
2316 Male, age 76, right hemisphere 311.2
2407 Male, age 75, both hemispheres 307.9
2273 Male, age 74, both hemispheres 294.4
1817 Female, age 42, unknown 284.5
1815 Male, age 53, unknown 278.0
2007 Male, age 72, unknown 274.1
2667 Female, age 75, unknown 274.1
1816 Male, age 51, unknown 256.1
1944 Female, age 72, unknown 242.0
Red nucleus
nTPM: 319.1
2503 Female, age 72, unknown 381.8
1821 Female, age 72, unknown 365.2
1865 Male, age 51, unknown 344.9
2588 Male, age 74, left hemisphere 318.3
2725 Female, age 75, unknown 317.4
2769 Male, age 72, unknown 316.9
2227 Male, age 72, unknown 314.0
2584 Male, age 75, left hemisphere 314.0
1904 Male, age 53, unknown 313.8
1954 Female, age 42, unknown 296.8
2785 Male, age 18, unknown 276.6
2823 Male, age 76, right hemisphere 269.7
Substantia nigra
nTPM: 390.7
2699 Male, age 18, unknown 455.0
2665 Male, age 74, both hemispheres 452.3
1851 Male, age 51, unknown 444.7
2241 Male, age 72, unknown 421.6
1916 Female, age 42, unknown 417.3
2590 Female, age 75, unknown 378.9
2409 Female, age 72, unknown 371.3
1941 Male, age 53, unknown 343.0
2583 Male, age 75, right hemisphere 327.2
1889 Female, age 72, unknown 295.9
Superior colliculus
nTPM: 317.5
2664 Male, age 75, both hemispheres 385.5
2587 Male, age 74, left hemisphere 375.0
1839 Male, age 51, unknown 337.8
1995 Male, age 72, unknown 322.1
2668 Female, age 75, unknown 317.1
1913 Female, age 42, unknown 314.6
1796 Male, age 53, unknown 303.4
1895 Male, age 76, right hemisphere 295.2
2261 Male, age 18, unknown 264.7
2087 Female, age 72, unknown 259.3
Ventral tegmental area
nTPM: 361.0
1915 Female, age 42, unknown 427.2
2021 Male, age 53, unknown 378.9
2223 Female, age 72, unknown 360.5
2410 Female, age 72, unknown 346.0
1942 Male, age 51, unknown 345.0
2218 Male, age 76, both hemispheres 308.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

704.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 704.1
Samples: 139

Max nTPM: 1742.8
Min nTPM: 396.7
Std nTPM: 217.8
Median nTPM: 682.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1742.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1710.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1623.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1230.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1099.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1076.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1063.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1026.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1001.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 997.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 992.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 975.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 962.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 958.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 951.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 936.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 925.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 907.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 903.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 903.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 890.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 861.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 856.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 834.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 825.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 821.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 818.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 815.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 810.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 803.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 802.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 781.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 779.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 773.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 771.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 769.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 767.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 765.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 765.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 763.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 761.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 756.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 753.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 747.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 746.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 744.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 737.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 729.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 726.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 725.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 723.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 722.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 719.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 718.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 715.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 712.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 708.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 706.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 699.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 698.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 698.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 695.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 692.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 691.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 691.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 690.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 689.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 688.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 684.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 682.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 667.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 663.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 662.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 659.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 652.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 650.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 648.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 645.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 639.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 639.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 639.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 635.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 634.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 633.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 623.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 622.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 620.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 615.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 612.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 612.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 610.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 605.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 601.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 594.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 592.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 592.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 586.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 585.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 581.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 575.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 571.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 566.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 565.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 562.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 559.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 553.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 553.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 547.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 542.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 539.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 536.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 534.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 533.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 532.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 530.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 524.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 519.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 517.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 511.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 503.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 502.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 500.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 500.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 498.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 494.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 491.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 489.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 483.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 475.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 474.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 462.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 460.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 459.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 458.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 438.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 425.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 416.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 414.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 396.7
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

17.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 17.2
FF:10158-103A5 76 years, female 17.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

320.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 305.6
Samples: 4

Max nTPM: 415.3
Min nTPM: 255.9
Sample A Female 415.3
Sample B Female 291.2
Sample C Male 255.9
Sample D Male 259.9
Midbrain
nTPM: 302.6
Samples: 4

Max nTPM: 439.3
Min nTPM: 227.7
Sample A Female 439.3
Sample B Female 311.5
Sample C Male 232.0
Sample D Male 227.7
Periaqueductal gray
nTPM: 250.2
Samples: 3

Max nTPM: 270.1
Min nTPM: 228.6
Sample B Female 251.8
Sample C Male 270.1
Sample D Male 228.6
Superior colliculi
nTPM: 320.0
Samples: 4

Max nTPM: 394.9
Min nTPM: 261.0
Sample A Female 394.9
Sample B Female 332.4
Sample C Male 261.0
Sample D Male 291.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

345.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 345.4
Samples: 4

Max nTPM: 368.8
Min nTPM: 331.8
Sample A Male 368.8
Sample B Male 346.5
Sample C Female 331.8
Sample D Female 334.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

14.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 14.5
74819238 Antisense, RP_060315_02_C02, Mouse strain C57BL/6J (56 days, male) 17.7
68441520 Antisense, RP_041214_02_E05, Mouse strain C57BL/6J (56 days, male) 11.4

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