In a publication in Genome Biology, HPA related researchers present an integrated resource that maps gene expression across the human body using both single cell and bulk RNA sequencing data. The study covers 31 tissues and identifies over 557 distinct cell clusters, each annotated and validated using known marker genes and antibody-based profiling...Read more

Specific expression of L1 cell adhesion molecule (gene: L1CAM) in collecting duct cells in the kidney is highlighted with multiplex immunohistochemistry (mIHC/IF)...Read more

Mitosis is the fundamental process by which genetic information is passed from a parental cell to two daughter cells. The crucial role of the microtubule cytoskeleton and the centrosomes in this process is well known, and still early mouse embryo lack centrosomes. In a study published in Cell researches have found an explanation to this paradox...Read more

Recently, Sweden's leading business newspaper Dagens Industri published an in-depth interview with HPA Director, professor Mathias Uhlén, about the global race to build a virtual cell - a next frontier in biomedical AI. The article compares major global initiatives such as AlphaFold, the Chan Zuckerberg Initiative, and China's Pi-HuB project, and highlights the Swedish effort Alpha Cell...Read more

The cell cycle is fundamental for life, enabling organisms to grow, heal, reproduce, and maintain cellular function. In the subcellular resource of the Human Protein Atlas protein imaging and single cell RNAseq analysis have been used to explore cell-to-cell variability and the cell cycle dependent proteome...Read more