In a publication in Molecular Systems Biology HPA related researchers review the recent application of AI and systems biology in integrating and interpreting multi-omics data and their contributions to drug discovery. The newly generated longitudinal multi-omics datasets that are needed for these analyses and to enhance precision health and medicine are also described...Read more

Cancer is a leading cause of death in every country of the world and hepatocellular carcinoma (HCC) is third in line in terms of mortality (Sung, 2021). In the past few years, immunotherapy with immune checkpoint inhibitors (ICIs) has become a common treatment route for HCC, but a large proportion of patients are resistant to such treatments...Read more

In an article published in the journal Immunity HPA related researchers have analyzed plasma proteins in adults during and after acute malaria and by integrating the profiles with single-cell RNA-seq data they have been able to link responses to peripheral immune cells and identify a protein profile enriched in severe malaria...Read more

In this edition of multiplex image of this month, Ciliogenesis-associated regulatory factor X2 (gene:RFX2) is visualized in ciliated epithelium of the nasopharynx...Read more