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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:530.9 nTPM
HPA Brain:552.0 nTPM
GTEx:530.9 nTPM
FANTOM5:500.3 Scaled Tags Per Million
Pig:495.6 nTPM
Mouse:690.0 nTPM
Allen mouse:1.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

552.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 357.5
2411 Female, age 72, unknown 446.5
1870 Female, age 42, unknown 387.4
2586 Male, age 75, left hemisphere 384.8
1827 Male, age 72, unknown 372.9
2828 Female, age 72, unknown 363.8
2019 Male, age 18, unknown 337.2
1833 Male, age 53, unknown 332.7
2666 Male, age 74, left hemisphere 323.8
2219 Male, age 76, both hemispheres 322.6
1830 Male, age 51, unknown 303.0
Dorsal raphe nucleus
nTPM: 552.0
2298 Female, age 72, unknown 736.3
2047 Male, age 72, unknown 612.3
1828 Male, age 53, unknown 521.2
2016 Female, age 72, unknown 468.6
2750 Male, age 76, both hemispheres 421.3
Inferior colliculus
nTPM: 467.2
2097 Female, age 72, unknown 620.4
1890 Male, age 53, unknown 529.6
1848 Female, age 42, unknown 393.5
2849 Male, age 72, unknown 325.3
Median raphe nucleus
nTPM: 505.8
2220 Male, age 76, midline 505.8
Periaquaductal grey, anterior
nTPM: 411.3
1947 Male, age 18, unknown 437.7
1795 Male, age 51, unknown 432.0
2502 Female, age 75, unknown 364.1
Periaquaductal grey, dorsal
nTPM: 394.7
2850 Male, age 76, both hemispheres 467.3
1840 Male, age 53, unknown 405.7
2464 Female, age 72, unknown 362.6
1831 Male, age 72, unknown 343.2
Periaquaductal grey, lateral
nTPM: 408.1
2272 Male, age 74, both hemispheres 470.2
2140 Male, age 76, both hemispheres 395.6
2053 Male, age 18, unknown 358.6
Pretectal area
nTPM: 395.9
2667 Female, age 75, unknown 509.1
2273 Male, age 74, both hemispheres 507.5
2224 Female, age 72, unknown 482.7
1817 Female, age 42, unknown 418.4
1944 Female, age 72, unknown 408.6
1816 Male, age 51, unknown 388.8
2825 Male, age 18, unknown 369.4
2007 Male, age 72, unknown 367.0
2316 Male, age 76, right hemisphere 319.8
1815 Male, age 53, unknown 310.7
2407 Male, age 75, both hemispheres 273.1
Red nucleus
nTPM: 363.6
1821 Female, age 72, unknown 478.6
2725 Female, age 75, unknown 427.7
1954 Female, age 42, unknown 420.8
2227 Male, age 72, unknown 391.6
2769 Male, age 72, unknown 389.2
2503 Female, age 72, unknown 374.2
1865 Male, age 51, unknown 358.1
1904 Male, age 53, unknown 355.1
2823 Male, age 76, right hemisphere 336.0
2785 Male, age 18, unknown 334.1
2584 Male, age 75, left hemisphere 251.3
2588 Male, age 74, left hemisphere 247.1
Substantia nigra
nTPM: 456.4
1916 Female, age 42, unknown 686.6
1941 Male, age 53, unknown 543.0
2699 Male, age 18, unknown 500.9
1851 Male, age 51, unknown 499.3
2241 Male, age 72, unknown 499.2
1889 Female, age 72, unknown 442.2
2409 Female, age 72, unknown 378.3
2665 Male, age 74, both hemispheres 364.7
2590 Female, age 75, unknown 326.4
2583 Male, age 75, right hemisphere 323.3
Superior colliculus
nTPM: 346.1
2087 Female, age 72, unknown 393.4
2261 Male, age 18, unknown 383.6
1796 Male, age 53, unknown 374.4
1995 Male, age 72, unknown 364.3
1913 Female, age 42, unknown 355.8
2587 Male, age 74, left hemisphere 337.9
2668 Female, age 75, unknown 336.6
1839 Male, age 51, unknown 327.4
2664 Male, age 75, both hemispheres 305.4
1895 Male, age 76, right hemisphere 281.7
Ventral tegmental area
nTPM: 464.1
1915 Female, age 42, unknown 532.1
1942 Male, age 51, unknown 480.4
2410 Female, age 72, unknown 467.7
2223 Female, age 72, unknown 458.1
2218 Male, age 76, both hemispheres 444.8
2021 Male, age 53, unknown 401.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

530.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 530.9
Samples: 139

Max nTPM: 1253.5
Min nTPM: 244.0
Std nTPM: 161.6
Median nTPM: 511.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1253.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1055.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1050.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 936.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 918.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 823.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 812.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 805.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 758.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 747.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 746.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 741.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 737.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 714.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 708.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 708.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 696.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 686.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 684.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 675.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 671.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 665.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 661.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 660.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 654.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 652.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 651.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 643.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 642.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 640.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 633.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 621.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 620.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 615.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 615.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 614.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 611.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 610.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 603.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 601.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 601.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 593.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 592.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 590.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 589.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 580.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 580.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 579.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 578.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 567.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 567.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 566.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 562.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 561.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 559.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 559.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 548.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 548.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 543.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 542.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 539.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 538.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 535.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 530.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 526.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 523.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 522.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 516.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 515.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 511.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 506.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 503.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 503.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 499.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 499.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 498.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 496.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 496.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 495.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 494.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 492.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 476.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 469.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 464.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 462.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 461.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 459.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 452.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 452.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 450.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 450.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 449.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 448.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 447.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 444.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 443.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 441.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 434.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 430.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 429.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 426.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 426.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 422.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 418.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 409.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 408.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 402.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 401.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 397.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 392.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 389.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 385.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 384.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 381.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 380.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 380.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 379.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 377.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 375.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 373.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 372.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 370.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 358.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 357.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 350.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 348.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 347.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 346.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 344.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 338.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 320.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 316.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 312.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 311.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 301.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 300.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 289.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 274.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 244.0
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

500.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 500.3
FF:10158-103A5 76 years, female 500.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

495.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 473.3
Samples: 4

Max nTPM: 559.5
Min nTPM: 358.8
Sample A Female 559.5
Sample B Female 358.8
Sample C Male 488.9
Sample D Male 485.9
Midbrain
nTPM: 495.4
Samples: 4

Max nTPM: 716.4
Min nTPM: 377.3
Sample A Female 716.4
Sample B Female 448.4
Sample C Male 439.5
Sample D Male 377.3
Periaqueductal gray
nTPM: 376.9
Samples: 3

Max nTPM: 426.0
Min nTPM: 314.7
Sample B Female 389.9
Sample C Male 426.0
Sample D Male 314.7
Superior colliculi
nTPM: 495.6
Samples: 4

Max nTPM: 598.1
Min nTPM: 423.3
Sample A Female 598.1
Sample B Female 423.3
Sample C Male 499.2
Sample D Male 461.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

690.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 690.0
Samples: 4

Max nTPM: 727.4
Min nTPM: 650.7
Sample A Male 727.4
Sample B Male 663.3
Sample C Female 650.7
Sample D Female 718.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.5
74822850 Antisense, RP_050921_03_C01, Mouse strain C57BL/6J (56 days, male) 1.5

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