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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:130.8 nTPM
HPA Brain:408.6 nTPM
GTEx:130.8 nTPM
FANTOM5:163.7 Scaled Tags Per Million
Pig:527.1 nTPM
Mouse:267.3 nTPM
Allen mouse:18.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

408.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 267.9
2411 Female, age 72, unknown 356.5
1827 Male, age 72, unknown 323.1
1870 Female, age 42, unknown 299.3
1833 Male, age 53, unknown 270.0
2219 Male, age 76, both hemispheres 267.1
2828 Female, age 72, unknown 250.1
2666 Male, age 74, left hemisphere 235.5
1830 Male, age 51, unknown 234.5
2586 Male, age 75, left hemisphere 225.4
2019 Male, age 18, unknown 217.1
Dorsal raphe nucleus
nTPM: 360.9
2298 Female, age 72, unknown 554.5
2047 Male, age 72, unknown 365.8
2750 Male, age 76, both hemispheres 311.9
1828 Male, age 53, unknown 286.7
2016 Female, age 72, unknown 285.3
Inferior colliculus
nTPM: 330.0
2097 Female, age 72, unknown 419.8
2849 Male, age 72, unknown 323.6
1848 Female, age 42, unknown 299.0
1890 Male, age 53, unknown 277.4
Median raphe nucleus
nTPM: 408.6
2220 Male, age 76, midline 408.6
Periaquaductal grey, anterior
nTPM: 377.6
1947 Male, age 18, unknown 411.0
1795 Male, age 51, unknown 385.4
2502 Female, age 75, unknown 336.5
Periaquaductal grey, dorsal
nTPM: 341.9
1840 Male, age 53, unknown 413.1
2850 Male, age 76, both hemispheres 364.3
2464 Female, age 72, unknown 306.1
1831 Male, age 72, unknown 284.1
Periaquaductal grey, lateral
nTPM: 338.9
2272 Male, age 74, both hemispheres 394.8
2140 Male, age 76, both hemispheres 333.5
2053 Male, age 18, unknown 288.5
Pretectal area
nTPM: 333.1
2224 Female, age 72, unknown 508.0
2273 Male, age 74, both hemispheres 490.7
2825 Male, age 18, unknown 370.4
2667 Female, age 75, unknown 360.6
2007 Male, age 72, unknown 305.0
1816 Male, age 51, unknown 297.4
1817 Female, age 42, unknown 280.7
1944 Female, age 72, unknown 266.1
2407 Male, age 75, both hemispheres 265.0
2316 Male, age 76, right hemisphere 262.5
1815 Male, age 53, unknown 257.4
Red nucleus
nTPM: 194.4
2725 Female, age 75, unknown 238.1
2785 Male, age 18, unknown 220.7
2227 Male, age 72, unknown 214.9
2769 Male, age 72, unknown 214.1
2503 Female, age 72, unknown 212.1
2584 Male, age 75, left hemisphere 202.5
1821 Female, age 72, unknown 198.0
1954 Female, age 42, unknown 181.1
1904 Male, age 53, unknown 175.7
2823 Male, age 76, right hemisphere 168.9
2588 Male, age 74, left hemisphere 154.8
1865 Male, age 51, unknown 151.9
Substantia nigra
nTPM: 226.1
1941 Male, age 53, unknown 280.2
1889 Female, age 72, unknown 276.5
1916 Female, age 42, unknown 271.5
1851 Male, age 51, unknown 256.4
2241 Male, age 72, unknown 226.5
2665 Male, age 74, both hemispheres 214.5
2583 Male, age 75, right hemisphere 202.5
2699 Male, age 18, unknown 199.0
2590 Female, age 75, unknown 187.2
2409 Female, age 72, unknown 146.4
Superior colliculus
nTPM: 275.1
1796 Male, age 53, unknown 339.6
1839 Male, age 51, unknown 324.0
2261 Male, age 18, unknown 300.3
2587 Male, age 74, left hemisphere 289.6
2664 Male, age 75, both hemispheres 281.8
1895 Male, age 76, right hemisphere 279.0
2668 Female, age 75, unknown 261.6
2087 Female, age 72, unknown 254.4
1995 Male, age 72, unknown 213.1
1913 Female, age 42, unknown 207.6
Ventral tegmental area
nTPM: 290.3
1942 Male, age 51, unknown 319.2
2218 Male, age 76, both hemispheres 303.9
1915 Female, age 42, unknown 302.2
2021 Male, age 53, unknown 290.0
2410 Female, age 72, unknown 275.8
2223 Female, age 72, unknown 250.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

130.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 130.8
Samples: 139

Max nTPM: 374.8
Min nTPM: 41.8
Std nTPM: 63.8
Median nTPM: 112.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 374.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 361.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 305.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 304.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 280.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 261.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 252.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 243.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 235.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 227.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 224.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 219.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 213.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 209.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 209.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 206.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 205.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 202.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 200.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 197.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 196.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 192.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 192.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 190.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 189.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 189.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 188.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 188.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 182.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 180.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 179.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 177.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 174.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 174.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 168.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 164.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 162.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 157.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 155.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 151.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 150.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 150.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 150.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 149.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 149.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 146.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 146.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 146.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 144.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 143.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 142.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 142.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 140.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 139.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 138.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 138.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 138.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 137.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 136.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 135.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 135.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 135.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 130.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 128.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 119.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 118.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 117.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 115.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 112.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 112.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 111.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 111.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 110.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 109.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 106.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 105.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 105.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 103.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 103.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 102.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 101.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 101.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 100.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 100.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 99.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 97.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 97.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 96.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 95.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 94.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 93.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 90.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 90.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 89.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 88.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 88.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 87.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 86.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 86.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 86.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 86.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 84.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 82.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 81.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 81.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 80.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 80.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 80.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 79.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 75.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 75.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 75.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 75.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 74.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 74.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 73.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 72.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 72.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 72.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 70.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 70.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 69.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 69.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 68.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 65.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 63.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 62.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 61.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 60.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 58.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 57.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 57.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 57.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 54.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 52.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 49.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 45.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 44.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 41.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

163.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 163.7
FF:10158-103A5 76 years, female 163.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

527.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 527.2
Samples: 4

Max nTPM: 735.3
Min nTPM: 328.8
Sample A Female 735.3
Sample B Female 384.1
Sample C Male 660.4
Sample D Male 328.8
Midbrain
nTPM: 507.1
Samples: 4

Max nTPM: 632.6
Min nTPM: 413.5
Sample A Female 466.0
Sample B Female 413.5
Sample C Male 516.1
Sample D Male 632.6
Periaqueductal gray
nTPM: 433.4
Samples: 3

Max nTPM: 523.1
Min nTPM: 380.8
Sample B Female 380.8
Sample C Male 523.1
Sample D Male 396.2
Superior colliculi
nTPM: 481.0
Samples: 4

Max nTPM: 653.4
Min nTPM: 352.9
Sample A Female 653.4
Sample B Female 352.9
Sample C Male 433.0
Sample D Male 484.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

267.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 267.3
Samples: 4

Max nTPM: 287.2
Min nTPM: 250.4
Sample A Male 287.2
Sample B Male 257.0
Sample C Female 250.4
Sample D Female 274.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

18.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 18.3
74635072 Antisense, RP_060215_03_C09, Mouse strain C57BL/6J (56 days, male) 18.3

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