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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:100.9 nTPM
HPA Brain:167.0 nTPM
GTEx:100.9 nTPM
FANTOM5:23.6 Scaled Tags Per Million
Pig:99.8 nTPM
Mouse:315.9 nTPM
Allen mouse:14.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

167.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 96.1
2219 Male, age 76, both hemispheres 121.9
1827 Male, age 72, unknown 118.5
2411 Female, age 72, unknown 118.1
2666 Male, age 74, left hemisphere 108.5
2828 Female, age 72, unknown 103.0
2019 Male, age 18, unknown 93.7
1870 Female, age 42, unknown 82.7
1833 Male, age 53, unknown 78.5
1830 Male, age 51, unknown 68.6
2586 Male, age 75, left hemisphere 67.6
Dorsal raphe nucleus
nTPM: 120.0
2298 Female, age 72, unknown 165.9
2750 Male, age 76, both hemispheres 140.7
2047 Male, age 72, unknown 129.6
1828 Male, age 53, unknown 100.7
2016 Female, age 72, unknown 63.1
Inferior colliculus
nTPM: 81.3
2097 Female, age 72, unknown 107.0
1848 Female, age 42, unknown 79.7
1890 Male, age 53, unknown 71.4
2849 Male, age 72, unknown 67.1
Median raphe nucleus
nTPM: 167.0
2220 Male, age 76, midline 167.0
Periaquaductal grey, anterior
nTPM: 119.8
1795 Male, age 51, unknown 132.5
1947 Male, age 18, unknown 120.9
2502 Female, age 75, unknown 106.0
Periaquaductal grey, dorsal
nTPM: 75.1
1840 Male, age 53, unknown 84.4
1831 Male, age 72, unknown 78.1
2850 Male, age 76, both hemispheres 70.1
2464 Female, age 72, unknown 67.7
Periaquaductal grey, lateral
nTPM: 67.6
2053 Male, age 18, unknown 71.3
2272 Male, age 74, both hemispheres 68.6
2140 Male, age 76, both hemispheres 63.1
Pretectal area
nTPM: 108.5
1816 Male, age 51, unknown 165.2
1944 Female, age 72, unknown 159.3
2007 Male, age 72, unknown 141.4
2667 Female, age 75, unknown 140.6
1817 Female, age 42, unknown 136.1
1815 Male, age 53, unknown 111.3
2224 Female, age 72, unknown 103.8
2825 Male, age 18, unknown 78.2
2316 Male, age 76, right hemisphere 57.0
2273 Male, age 74, both hemispheres 56.0
2407 Male, age 75, both hemispheres 44.5
Red nucleus
nTPM: 76.3
1821 Female, age 72, unknown 97.2
2785 Male, age 18, unknown 89.5
2584 Male, age 75, left hemisphere 87.0
1954 Female, age 42, unknown 83.3
2227 Male, age 72, unknown 74.7
2769 Male, age 72, unknown 73.3
2503 Female, age 72, unknown 73.1
1904 Male, age 53, unknown 70.5
2588 Male, age 74, left hemisphere 70.5
1865 Male, age 51, unknown 66.3
2823 Male, age 76, right hemisphere 65.5
2725 Female, age 75, unknown 64.9
Substantia nigra
nTPM: 142.6
1916 Female, age 42, unknown 235.9
2665 Male, age 74, both hemispheres 197.8
1941 Male, age 53, unknown 169.1
1851 Male, age 51, unknown 166.9
1889 Female, age 72, unknown 138.3
2409 Female, age 72, unknown 138.0
2241 Male, age 72, unknown 120.6
2699 Male, age 18, unknown 101.6
2590 Female, age 75, unknown 83.9
2583 Male, age 75, right hemisphere 74.2
Superior colliculus
nTPM: 88.5
2087 Female, age 72, unknown 143.0
1796 Male, age 53, unknown 123.0
2668 Female, age 75, unknown 122.9
2261 Male, age 18, unknown 110.6
1895 Male, age 76, right hemisphere 83.4
1913 Female, age 42, unknown 70.6
1839 Male, age 51, unknown 70.1
2587 Male, age 74, left hemisphere 62.5
1995 Male, age 72, unknown 53.9
2664 Male, age 75, both hemispheres 45.6
Ventral tegmental area
nTPM: 130.8
2410 Female, age 72, unknown 192.9
2218 Male, age 76, both hemispheres 174.9
1915 Female, age 42, unknown 149.4
1942 Male, age 51, unknown 99.4
2021 Male, age 53, unknown 85.3
2223 Female, age 72, unknown 83.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

100.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 100.9
Samples: 139

Max nTPM: 414.3
Min nTPM: 13.2
Std nTPM: 85.1
Median nTPM: 72.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 414.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 407.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 347.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 331.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 283.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 278.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 276.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 271.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 263.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 250.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 233.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 226.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 222.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 217.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 212.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 211.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 209.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 203.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 201.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 201.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 200.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 200.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 196.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 193.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 174.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 169.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 168.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 164.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 164.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 158.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 153.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 150.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 150.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 147.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 140.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 137.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 136.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 134.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 133.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 131.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 131.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 128.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 127.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 126.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 124.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 123.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 121.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 120.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 118.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 116.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 116.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 112.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 110.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 105.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 101.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 98.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 97.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 95.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 94.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 94.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 92.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 86.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 86.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 84.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 84.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 76.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 75.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 74.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 73.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 72.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 71.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 69.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 67.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 66.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 65.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 63.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 62.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 58.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 56.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 56.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 55.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 55.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 54.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 53.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 48.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 48.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 47.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 46.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 46.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 45.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 44.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 42.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 41.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 40.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 40.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 38.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 38.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 37.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 36.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 36.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 35.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 34.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 33.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 32.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 31.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 31.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 30.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 30.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 29.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 28.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 28.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 28.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 27.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 26.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 26.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 26.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 26.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 25.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 25.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 24.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 24.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 23.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 22.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 21.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 21.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 21.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 21.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 20.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 20.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 19.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 19.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 18.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 18.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 17.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 17.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 16.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 16.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 13.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 13.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

23.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 23.6
FF:10158-103A5 76 years, female 23.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

99.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 99.8
Samples: 4

Max nTPM: 162.7
Min nTPM: 20.8
Sample A Female 162.7
Sample B Female 65.4
Sample C Male 150.2
Sample D Male 20.8
Midbrain
nTPM: 84.5
Samples: 4

Max nTPM: 157.9
Min nTPM: 18.0
Sample A Female 18.0
Sample B Female 66.1
Sample C Male 157.9
Sample D Male 96.1
Periaqueductal gray
nTPM: 65.9
Samples: 3

Max nTPM: 97.4
Min nTPM: 47.3
Sample B Female 53.0
Sample C Male 97.4
Sample D Male 47.3
Superior colliculi
nTPM: 93.3
Samples: 4

Max nTPM: 143.2
Min nTPM: 55.3
Sample A Female 89.9
Sample B Female 55.3
Sample C Male 143.2
Sample D Male 84.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

315.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 315.9
Samples: 4

Max nTPM: 337.2
Min nTPM: 291.6
Sample A Male 337.2
Sample B Male 302.4
Sample C Female 291.6
Sample D Female 332.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

14.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 14.6
146 Antisense, RP_040315_01_11, Mouse strain C57BL/6J (56 days, male) 14.6
145 Antisense, RP_040315_01_11, Mouse strain C57BL/6J (56 days, male) 13.2

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