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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:478.9 nTPM
HPA Brain:982.4 nTPM
GTEx:478.9 nTPM
FANTOM5:650.0 Scaled Tags Per Million
Pig:909.6 nTPM
Mouse:657.5 nTPM
Allen mouse:26.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

982.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 722.5
2411 Female, age 72, unknown 1025.9
1870 Female, age 42, unknown 873.4
1830 Male, age 51, unknown 869.5
2019 Male, age 18, unknown 848.6
1833 Male, age 53, unknown 825.0
2828 Female, age 72, unknown 628.5
2666 Male, age 74, left hemisphere 562.8
2586 Male, age 75, left hemisphere 556.8
1827 Male, age 72, unknown 539.6
2219 Male, age 76, both hemispheres 495.4
Dorsal raphe nucleus
nTPM: 566.9
2750 Male, age 76, both hemispheres 1031.9
1828 Male, age 53, unknown 506.3
2016 Female, age 72, unknown 479.4
2047 Male, age 72, unknown 420.0
2298 Female, age 72, unknown 397.0
Inferior colliculus
nTPM: 489.3
1848 Female, age 42, unknown 519.3
1890 Male, age 53, unknown 500.3
2849 Male, age 72, unknown 473.2
2097 Female, age 72, unknown 464.5
Median raphe nucleus
nTPM: 525.8
2220 Male, age 76, midline 525.8
Periaquaductal grey, anterior
nTPM: 432.3
1947 Male, age 18, unknown 500.1
2502 Female, age 75, unknown 399.1
1795 Male, age 51, unknown 397.6
Periaquaductal grey, dorsal
nTPM: 359.6
2464 Female, age 72, unknown 513.8
1831 Male, age 72, unknown 393.0
1840 Male, age 53, unknown 290.5
2850 Male, age 76, both hemispheres 241.2
Periaquaductal grey, lateral
nTPM: 432.2
2272 Male, age 74, both hemispheres 568.8
2053 Male, age 18, unknown 472.5
2140 Male, age 76, both hemispheres 255.5
Pretectal area
nTPM: 496.6
2316 Male, age 76, right hemisphere 615.3
1815 Male, age 53, unknown 613.7
2407 Male, age 75, both hemispheres 610.6
2007 Male, age 72, unknown 577.1
1817 Female, age 42, unknown 544.0
2273 Male, age 74, both hemispheres 502.8
2825 Male, age 18, unknown 501.0
2224 Female, age 72, unknown 428.8
2667 Female, age 75, unknown 391.2
1816 Male, age 51, unknown 339.5
1944 Female, age 72, unknown 338.5
Red nucleus
nTPM: 982.4
1865 Male, age 51, unknown 1134.1
1904 Male, age 53, unknown 1093.4
1821 Female, age 72, unknown 1074.0
2769 Male, age 72, unknown 1070.1
2823 Male, age 76, right hemisphere 1034.6
2227 Male, age 72, unknown 1033.8
2503 Female, age 72, unknown 986.4
2785 Male, age 18, unknown 969.2
2588 Male, age 74, left hemisphere 920.1
1954 Female, age 42, unknown 885.1
2584 Male, age 75, left hemisphere 831.6
2725 Female, age 75, unknown 756.4
Substantia nigra
nTPM: 533.8
2583 Male, age 75, right hemisphere 818.0
2590 Female, age 75, unknown 755.5
1851 Male, age 51, unknown 612.1
1889 Female, age 72, unknown 594.6
2409 Female, age 72, unknown 539.8
1941 Male, age 53, unknown 487.6
1916 Female, age 42, unknown 430.0
2699 Male, age 18, unknown 405.3
2241 Male, age 72, unknown 385.7
2665 Male, age 74, both hemispheres 309.4
Superior colliculus
nTPM: 611.4
1913 Female, age 42, unknown 862.0
1995 Male, age 72, unknown 835.1
2587 Male, age 74, left hemisphere 727.4
2668 Female, age 75, unknown 683.0
1895 Male, age 76, right hemisphere 677.8
1839 Male, age 51, unknown 625.4
1796 Male, age 53, unknown 539.8
2261 Male, age 18, unknown 443.4
2087 Female, age 72, unknown 375.5
2664 Male, age 75, both hemispheres 344.5
Ventral tegmental area
nTPM: 679.7
2223 Female, age 72, unknown 1134.1
2410 Female, age 72, unknown 796.7
2218 Male, age 76, both hemispheres 549.3
1942 Male, age 51, unknown 544.3
2021 Male, age 53, unknown 538.0
1915 Female, age 42, unknown 516.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

478.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 478.9
Samples: 139

Max nTPM: 1725.9
Min nTPM: 109.3
Std nTPM: 275.3
Median nTPM: 418.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1725.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1438.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1267.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1233.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1041.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1019.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1001.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 986.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 984.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 979.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 973.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 951.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 891.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 882.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 860.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 834.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 796.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 794.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 775.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 768.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 748.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 728.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 714.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 712.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 710.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 694.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 690.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 685.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 681.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 677.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 667.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 666.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 626.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 585.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 582.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 567.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 557.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 557.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 549.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 544.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 540.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 538.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 537.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 534.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 528.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 522.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 521.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 507.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 496.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 486.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 476.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 475.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 474.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 468.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 456.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 455.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 449.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 446.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 443.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 440.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 436.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 433.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 433.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 432.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 430.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 429.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 425.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 425.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 421.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 418.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 417.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 415.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 409.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 409.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 401.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 392.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 380.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 373.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 372.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 359.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 358.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 356.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 355.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 348.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 339.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 334.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 330.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 325.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 323.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 322.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 321.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 318.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 312.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 306.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 303.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 300.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 293.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 291.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 290.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 290.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 286.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 285.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 275.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 272.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 272.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 272.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 271.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 269.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 267.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 265.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 263.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 262.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 260.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 250.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 247.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 246.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 245.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 244.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 243.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 242.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 234.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 232.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 232.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 226.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 226.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 221.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 219.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 215.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 214.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 212.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 211.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 191.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 172.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 172.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 167.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 167.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 153.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 144.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 109.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

650.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 650.0
FF:10158-103A5 76 years, female 650.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

909.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 727.9
Samples: 4

Max nTPM: 1166.8
Min nTPM: 380.8
Sample A Female 766.2
Sample B Female 380.8
Sample C Male 597.9
Sample D Male 1166.8
Midbrain
nTPM: 909.6
Samples: 4

Max nTPM: 1849.1
Min nTPM: 525.1
Sample A Female 1849.1
Sample B Female 681.9
Sample C Male 525.1
Sample D Male 582.2
Periaqueductal gray
nTPM: 504.2
Samples: 3

Max nTPM: 558.7
Min nTPM: 440.7
Sample B Female 558.7
Sample C Male 440.7
Sample D Male 513.2
Superior colliculi
nTPM: 683.0
Samples: 4

Max nTPM: 859.3
Min nTPM: 351.6
Sample A Female 859.3
Sample B Female 351.6
Sample C Male 682.9
Sample D Male 838.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

657.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 657.5
Samples: 4

Max nTPM: 678.4
Min nTPM: 614.4
Sample A Male 667.4
Sample B Male 614.4
Sample C Female 669.6
Sample D Female 678.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

26.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 26.8
69015613 Antisense, RP_050315_01_C12, Mouse strain C57BL/6J (56 days, male) 26.8

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