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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:382.5 nTPM
HPA Brain:444.9 nTPM
GTEx:382.5 nTPM
FANTOM5:133.5 Scaled Tags Per Million
Pig:312.0 nTPM
Mouse:141.2 nTPM
Allen mouse:0.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

444.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 427.9
2586 Male, age 75, left hemisphere 644.5
2666 Male, age 74, left hemisphere 533.4
1827 Male, age 72, unknown 522.8
2828 Female, age 72, unknown 464.1
2411 Female, age 72, unknown 383.2
1870 Female, age 42, unknown 373.3
1833 Male, age 53, unknown 351.9
2019 Male, age 18, unknown 345.9
1830 Male, age 51, unknown 331.9
2219 Male, age 76, both hemispheres 328.0
Dorsal raphe nucleus
nTPM: 350.3
2298 Female, age 72, unknown 374.6
2047 Male, age 72, unknown 369.5
2750 Male, age 76, both hemispheres 341.9
1828 Male, age 53, unknown 338.4
2016 Female, age 72, unknown 327.0
Inferior colliculus
nTPM: 382.2
2849 Male, age 72, unknown 428.8
1848 Female, age 42, unknown 381.8
2097 Female, age 72, unknown 367.7
1890 Male, age 53, unknown 350.6
Median raphe nucleus
nTPM: 352.9
2220 Male, age 76, midline 352.9
Periaquaductal grey, anterior
nTPM: 444.9
1795 Male, age 51, unknown 474.1
1947 Male, age 18, unknown 448.5
2502 Female, age 75, unknown 412.2
Periaquaductal grey, dorsal
nTPM: 358.7
1840 Male, age 53, unknown 396.3
2464 Female, age 72, unknown 355.7
1831 Male, age 72, unknown 352.5
2850 Male, age 76, both hemispheres 330.2
Periaquaductal grey, lateral
nTPM: 317.0
2053 Male, age 18, unknown 373.8
2140 Male, age 76, both hemispheres 307.5
2272 Male, age 74, both hemispheres 269.7
Pretectal area
nTPM: 415.6
2007 Male, age 72, unknown 532.2
1816 Male, age 51, unknown 531.6
1817 Female, age 42, unknown 491.9
1944 Female, age 72, unknown 460.8
1815 Male, age 53, unknown 456.3
2407 Male, age 75, both hemispheres 401.3
2825 Male, age 18, unknown 399.8
2667 Female, age 75, unknown 387.5
2224 Female, age 72, unknown 337.5
2316 Male, age 76, right hemisphere 303.5
2273 Male, age 74, both hemispheres 269.6
Red nucleus
nTPM: 354.4
2584 Male, age 75, left hemisphere 471.8
2588 Male, age 74, left hemisphere 433.4
2785 Male, age 18, unknown 388.3
2503 Female, age 72, unknown 366.9
2769 Male, age 72, unknown 351.2
1821 Female, age 72, unknown 339.8
2227 Male, age 72, unknown 337.7
2725 Female, age 75, unknown 335.8
1954 Female, age 42, unknown 310.0
2823 Male, age 76, right hemisphere 309.1
1865 Male, age 51, unknown 307.4
1904 Male, age 53, unknown 301.6
Substantia nigra
nTPM: 363.0
2665 Male, age 74, both hemispheres 453.1
2583 Male, age 75, right hemisphere 435.1
1889 Female, age 72, unknown 421.0
1941 Male, age 53, unknown 393.0
1916 Female, age 42, unknown 392.0
1851 Male, age 51, unknown 372.9
2590 Female, age 75, unknown 347.9
2699 Male, age 18, unknown 311.6
2409 Female, age 72, unknown 267.2
2241 Male, age 72, unknown 236.4
Superior colliculus
nTPM: 421.8
2664 Male, age 75, both hemispheres 566.1
2668 Female, age 75, unknown 503.6
1796 Male, age 53, unknown 483.5
2261 Male, age 18, unknown 438.7
2087 Female, age 72, unknown 405.5
1839 Male, age 51, unknown 387.5
1913 Female, age 42, unknown 368.6
1895 Male, age 76, right hemisphere 363.9
2587 Male, age 74, left hemisphere 362.1
1995 Male, age 72, unknown 338.8
Ventral tegmental area
nTPM: 348.7
1915 Female, age 42, unknown 382.5
1942 Male, age 51, unknown 366.9
2410 Female, age 72, unknown 346.3
2021 Male, age 53, unknown 338.5
2218 Male, age 76, both hemispheres 333.6
2223 Female, age 72, unknown 324.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

382.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 382.5
Samples: 139

Max nTPM: 762.7
Min nTPM: 217.7
Std nTPM: 81.2
Median nTPM: 375.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 762.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 669.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 559.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 548.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 535.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 533.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 532.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 531.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 524.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 498.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 492.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 490.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 485.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 482.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 478.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 477.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 474.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 471.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 467.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 465.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 465.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 457.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 454.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 452.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 450.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 449.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 447.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 446.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 445.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 443.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 440.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 435.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 429.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 426.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 425.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 424.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 415.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 413.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 413.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 410.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 409.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 408.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 405.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 403.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 403.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 401.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 401.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 398.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 398.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 397.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 396.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 392.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 392.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 391.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 391.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 391.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 389.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 388.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 387.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 386.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 386.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 386.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 385.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 385.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 383.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 382.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 380.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 377.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 376.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 375.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 373.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 371.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 369.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 368.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 360.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 359.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 358.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 357.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 357.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 357.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 355.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 351.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 351.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 351.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 350.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 348.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 348.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 347.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 346.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 343.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 343.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 341.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 341.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 341.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 339.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 338.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 338.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 338.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 338.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 337.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 336.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 333.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 332.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 332.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 332.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 330.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 329.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 326.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 326.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 325.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 323.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 321.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 320.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 320.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 317.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 316.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 313.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 313.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 311.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 311.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 311.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 308.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 291.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 289.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 285.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 284.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 284.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 283.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 281.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 281.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 280.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 275.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 274.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 272.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 253.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 240.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 238.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 233.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 217.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

133.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 133.5
FF:10158-103A5 76 years, female 133.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

312.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 244.2
Samples: 4

Max nTPM: 320.4
Min nTPM: 168.4
Sample A Female 320.4
Sample B Female 196.7
Sample C Male 291.2
Sample D Male 168.4
Midbrain
nTPM: 301.4
Samples: 4

Max nTPM: 367.9
Min nTPM: 244.3
Sample A Female 261.5
Sample B Female 244.3
Sample C Male 367.9
Sample D Male 332.0
Periaqueductal gray
nTPM: 229.9
Samples: 3

Max nTPM: 271.7
Min nTPM: 207.4
Sample B Female 207.4
Sample C Male 271.7
Sample D Male 210.6
Superior colliculi
nTPM: 312.0
Samples: 4

Max nTPM: 380.3
Min nTPM: 227.7
Sample A Female 380.3
Sample B Female 227.7
Sample C Male 335.5
Sample D Male 304.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

141.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 141.2
Samples: 4

Max nTPM: 171.6
Min nTPM: 116.0
Sample A Male 171.6
Sample B Male 130.6
Sample C Female 116.0
Sample D Female 146.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.3
71487112 Antisense, RP_050913_01_C07, Mouse strain C57BL/6J (56 days, male) 0.3

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