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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:1499.6 nTPM
HPA Brain:418.8 nTPM
GTEx:1499.6 nTPM
FANTOM5:523.9 Scaled Tags Per Million
Pig:434.0 nTPM
Mouse:465.4 nTPM
Allen mouse:2.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

418.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 338.5
2666 Male, age 74, left hemisphere 421.2
2411 Female, age 72, unknown 380.2
1870 Female, age 42, unknown 363.3
2586 Male, age 75, left hemisphere 362.0
2828 Female, age 72, unknown 359.3
1833 Male, age 53, unknown 313.9
1827 Male, age 72, unknown 312.6
1830 Male, age 51, unknown 304.1
2019 Male, age 18, unknown 301.6
2219 Male, age 76, both hemispheres 266.2
Dorsal raphe nucleus
nTPM: 319.3
2298 Female, age 72, unknown 351.4
2016 Female, age 72, unknown 349.2
2750 Male, age 76, both hemispheres 326.6
1828 Male, age 53, unknown 307.8
2047 Male, age 72, unknown 261.6
Inferior colliculus
nTPM: 287.8
1890 Male, age 53, unknown 342.0
2097 Female, age 72, unknown 283.9
1848 Female, age 42, unknown 269.7
2849 Male, age 72, unknown 255.4
Median raphe nucleus
nTPM: 284.8
2220 Male, age 76, midline 284.8
Periaquaductal grey, anterior
nTPM: 344.8
2502 Female, age 75, unknown 413.9
1795 Male, age 51, unknown 312.6
1947 Male, age 18, unknown 307.8
Periaquaductal grey, dorsal
nTPM: 318.7
1831 Male, age 72, unknown 345.6
1840 Male, age 53, unknown 335.9
2464 Female, age 72, unknown 302.3
2850 Male, age 76, both hemispheres 291.0
Periaquaductal grey, lateral
nTPM: 288.7
2053 Male, age 18, unknown 382.9
2140 Male, age 76, both hemispheres 279.1
2272 Male, age 74, both hemispheres 204.1
Pretectal area
nTPM: 319.9
1815 Male, age 53, unknown 376.4
1817 Female, age 42, unknown 357.9
2007 Male, age 72, unknown 344.0
2316 Male, age 76, right hemisphere 341.7
1816 Male, age 51, unknown 340.5
2407 Male, age 75, both hemispheres 316.3
2667 Female, age 75, unknown 309.1
1944 Female, age 72, unknown 301.3
2224 Female, age 72, unknown 300.4
2825 Male, age 18, unknown 297.9
2273 Male, age 74, both hemispheres 233.3
Red nucleus
nTPM: 402.1
2503 Female, age 72, unknown 559.0
1865 Male, age 51, unknown 442.8
1821 Female, age 72, unknown 441.9
1904 Male, age 53, unknown 420.9
2588 Male, age 74, left hemisphere 412.3
2725 Female, age 75, unknown 406.3
2584 Male, age 75, left hemisphere 392.9
2769 Male, age 72, unknown 390.4
2227 Male, age 72, unknown 365.5
2785 Male, age 18, unknown 346.4
2823 Male, age 76, right hemisphere 334.0
1954 Female, age 42, unknown 313.2
Substantia nigra
nTPM: 418.8
1851 Male, age 51, unknown 563.7
2699 Male, age 18, unknown 520.9
2409 Female, age 72, unknown 481.1
2241 Male, age 72, unknown 453.8
1916 Female, age 42, unknown 449.5
2665 Male, age 74, both hemispheres 408.4
2590 Female, age 75, unknown 352.7
1889 Female, age 72, unknown 348.8
2583 Male, age 75, right hemisphere 310.3
1941 Male, age 53, unknown 298.3
Superior colliculus
nTPM: 361.9
2587 Male, age 74, left hemisphere 462.8
1995 Male, age 72, unknown 443.3
1913 Female, age 42, unknown 442.2
1796 Male, age 53, unknown 347.9
2668 Female, age 75, unknown 344.7
2087 Female, age 72, unknown 324.1
2664 Male, age 75, both hemispheres 320.3
1839 Male, age 51, unknown 319.6
2261 Male, age 18, unknown 310.2
1895 Male, age 76, right hemisphere 303.7
Ventral tegmental area
nTPM: 381.1
1915 Female, age 42, unknown 454.6
2410 Female, age 72, unknown 418.3
2223 Female, age 72, unknown 408.8
2021 Male, age 53, unknown 371.1
2218 Male, age 76, both hemispheres 323.7
1942 Male, age 51, unknown 310.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1499.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1499.6
Samples: 139

Max nTPM: 5876.4
Min nTPM: 448.3
Std nTPM: 690.9
Median nTPM: 1382.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 5876.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 3935.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 3867.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 3176.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 2762.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 2715.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 2654.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 2549.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 2479.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 2365.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2326.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 2321.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 2308.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 2290.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2286.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 2214.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 2212.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 2174.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 2138.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 2114.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 2083.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1991.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1958.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1953.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1922.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1873.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1836.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1820.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1800.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1790.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1779.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1763.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1755.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1754.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1736.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1711.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1707.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1704.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1698.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1679.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1678.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1676.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1674.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1669.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1663.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1659.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1654.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1647.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1639.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1633.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1614.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1561.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1560.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1528.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1504.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1499.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1485.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1483.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1475.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1465.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1463.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1460.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1453.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1443.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1432.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1426.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1413.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1409.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1408.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1382.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1380.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1352.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1343.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1330.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1320.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1303.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1286.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1284.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1265.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1252.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1245.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1230.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1207.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1189.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1174.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1165.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1165.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1149.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1144.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 1129.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1127.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 1123.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 1123.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1109.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1107.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1107.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1104.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1100.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1096.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1076.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1072.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1070.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1065.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1060.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1057.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1041.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1037.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1036.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1029.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1026.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1021.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 1000.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 989.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 983.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 981.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 972.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 961.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 957.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 944.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 936.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 936.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 936.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 933.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 915.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 908.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 879.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 878.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 851.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 814.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 810.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 775.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 754.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 736.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 721.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 706.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 704.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 688.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 647.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 448.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

523.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 523.9
FF:10158-103A5 76 years, female 523.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

434.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 434.0
Samples: 4

Max nTPM: 550.6
Min nTPM: 353.5
Sample A Female 550.6
Sample B Female 464.2
Sample C Male 353.5
Sample D Male 367.7
Midbrain
nTPM: 394.8
Samples: 4

Max nTPM: 586.0
Min nTPM: 266.0
Sample A Female 586.0
Sample B Female 449.2
Sample C Male 277.8
Sample D Male 266.0
Periaqueductal gray
nTPM: 320.5
Samples: 3

Max nTPM: 365.2
Min nTPM: 287.1
Sample B Female 365.2
Sample C Male 309.2
Sample D Male 287.1
Superior colliculi
nTPM: 416.6
Samples: 4

Max nTPM: 468.8
Min nTPM: 348.1
Sample A Female 468.8
Sample B Female 467.4
Sample C Male 381.9
Sample D Male 348.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

465.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 465.4
Samples: 4

Max nTPM: 601.6
Min nTPM: 405.3
Sample A Male 601.6
Sample B Male 415.3
Sample C Female 405.3
Sample D Female 439.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.6
631721 Antisense, RP_040907_01_B12, Mouse strain C57BL/6J (56 days, male) 2.8
70928395 Antisense, RP_050808_02_A04, Mouse strain C57BL/6J (56 days, male) 2.4

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