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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:75.0 nTPM
HPA Brain:323.8 nTPM
GTEx:75.0 nTPM
FANTOM5:263.8 Scaled Tags Per Million
Pig:79.4 nTPM
Mouse:63.0 nTPM
Allen mouse:16.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

323.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 317.9
2666 Male, age 74, left hemisphere 389.2
2586 Male, age 75, left hemisphere 364.9
2828 Female, age 72, unknown 334.1
1833 Male, age 53, unknown 333.4
1830 Male, age 51, unknown 321.7
1827 Male, age 72, unknown 313.5
1870 Female, age 42, unknown 296.2
2219 Male, age 76, both hemispheres 278.3
2411 Female, age 72, unknown 276.3
2019 Male, age 18, unknown 271.5
Dorsal raphe nucleus
nTPM: 237.1
2750 Male, age 76, both hemispheres 308.9
1828 Male, age 53, unknown 266.0
2047 Male, age 72, unknown 226.8
2016 Female, age 72, unknown 199.6
2298 Female, age 72, unknown 184.1
Inferior colliculus
nTPM: 242.5
2849 Male, age 72, unknown 306.9
1890 Male, age 53, unknown 241.6
1848 Female, age 42, unknown 213.2
2097 Female, age 72, unknown 208.3
Median raphe nucleus
nTPM: 268.9
2220 Male, age 76, midline 268.9
Periaquaductal grey, anterior
nTPM: 267.6
1947 Male, age 18, unknown 278.4
1795 Male, age 51, unknown 269.0
2502 Female, age 75, unknown 255.4
Periaquaductal grey, dorsal
nTPM: 213.3
2464 Female, age 72, unknown 232.7
2850 Male, age 76, both hemispheres 232.2
1831 Male, age 72, unknown 232.1
1840 Male, age 53, unknown 156.3
Periaquaductal grey, lateral
nTPM: 195.9
2272 Male, age 74, both hemispheres 209.4
2053 Male, age 18, unknown 194.7
2140 Male, age 76, both hemispheres 183.5
Pretectal area
nTPM: 258.8
2667 Female, age 75, unknown 346.1
1815 Male, age 53, unknown 308.9
2407 Male, age 75, both hemispheres 298.1
1817 Female, age 42, unknown 277.8
2825 Male, age 18, unknown 271.3
1816 Male, age 51, unknown 266.5
2007 Male, age 72, unknown 264.9
1944 Female, age 72, unknown 244.2
2316 Male, age 76, right hemisphere 202.6
2224 Female, age 72, unknown 186.8
2273 Male, age 74, both hemispheres 179.5
Red nucleus
nTPM: 323.8
2584 Male, age 75, left hemisphere 404.1
2769 Male, age 72, unknown 346.7
2588 Male, age 74, left hemisphere 343.9
2823 Male, age 76, right hemisphere 337.9
2227 Male, age 72, unknown 330.6
1821 Female, age 72, unknown 320.5
1865 Male, age 51, unknown 314.2
1904 Male, age 53, unknown 311.5
2785 Male, age 18, unknown 304.3
2503 Female, age 72, unknown 294.8
1954 Female, age 42, unknown 289.1
2725 Female, age 75, unknown 288.0
Substantia nigra
nTPM: 282.6
2583 Male, age 75, right hemisphere 344.8
1916 Female, age 42, unknown 344.7
2699 Male, age 18, unknown 339.0
2665 Male, age 74, both hemispheres 337.7
1941 Male, age 53, unknown 313.0
1851 Male, age 51, unknown 304.3
1889 Female, age 72, unknown 255.1
2590 Female, age 75, unknown 225.0
2409 Female, age 72, unknown 193.5
2241 Male, age 72, unknown 168.9
Superior colliculus
nTPM: 270.9
2664 Male, age 75, both hemispheres 321.5
1913 Female, age 42, unknown 316.9
2668 Female, age 75, unknown 282.6
1995 Male, age 72, unknown 278.6
2587 Male, age 74, left hemisphere 270.2
1839 Male, age 51, unknown 268.1
1796 Male, age 53, unknown 256.3
1895 Male, age 76, right hemisphere 242.8
2261 Male, age 18, unknown 242.8
2087 Female, age 72, unknown 229.4
Ventral tegmental area
nTPM: 267.3
2223 Female, age 72, unknown 325.9
2218 Male, age 76, both hemispheres 292.9
1915 Female, age 42, unknown 276.9
2410 Female, age 72, unknown 248.6
2021 Male, age 53, unknown 229.9
1942 Male, age 51, unknown 229.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

75.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 75.0
Samples: 139

Max nTPM: 191.7
Min nTPM: 27.8
Std nTPM: 29.0
Median nTPM: 66.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 191.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 188.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 155.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 142.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 141.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 141.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 131.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 129.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 128.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 125.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 125.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 115.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 114.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 113.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 112.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 108.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 107.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 107.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 106.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 105.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 104.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 102.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 100.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 99.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 99.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 97.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 97.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 95.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 94.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 94.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 94.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 92.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 91.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 89.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 89.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 86.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 86.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 85.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 84.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 83.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 82.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 82.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 81.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 81.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 80.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 80.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 79.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 79.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 79.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 77.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 77.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 77.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 76.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 75.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 75.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 74.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 74.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 73.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 73.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 73.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 72.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 72.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 71.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 71.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 70.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 70.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 69.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 68.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 67.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 66.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 66.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 66.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 66.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 65.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 64.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 63.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 63.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 63.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 63.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 63.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 63.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 63.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 62.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 62.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 62.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 62.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 62.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 61.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 61.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 61.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 60.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 60.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 60.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 60.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 59.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 58.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 58.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 58.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 58.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 57.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 56.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 56.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 55.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 55.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 54.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 54.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 54.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 53.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 51.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 51.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 50.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 50.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 50.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 50.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 50.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 49.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 49.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 49.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 49.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 48.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 48.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 47.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 46.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 46.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 46.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 45.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 44.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 44.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 43.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 43.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 43.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 39.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 39.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 39.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 38.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 38.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 38.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 35.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 27.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

263.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 263.8
FF:10158-103A5 76 years, female 263.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

79.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 70.0
Samples: 4

Max nTPM: 78.6
Min nTPM: 49.9
Sample A Female 78.6
Sample B Female 49.9
Sample C Male 77.2
Sample D Male 74.3
Midbrain
nTPM: 79.4
Samples: 4

Max nTPM: 109.5
Min nTPM: 58.8
Sample A Female 109.5
Sample B Female 58.8
Sample C Male 79.6
Sample D Male 69.6
Periaqueductal gray
nTPM: 55.2
Samples: 3

Max nTPM: 60.0
Min nTPM: 51.3
Sample B Female 54.2
Sample C Male 60.0
Sample D Male 51.3
Superior colliculi
nTPM: 73.9
Samples: 4

Max nTPM: 81.3
Min nTPM: 54.4
Sample A Female 78.9
Sample B Female 54.4
Sample C Male 80.9
Sample D Male 81.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

63.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 63.0
Samples: 4

Max nTPM: 68.3
Min nTPM: 58.7
Sample A Male 68.3
Sample B Male 58.7
Sample C Female 61.7
Sample D Female 63.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

16.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 16.3
70429166 Antisense, RP_050614_01_B06, Mouse strain C57BL/6J (56 days, male) 16.3

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