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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:919.4 nTPM
HPA Brain:222.6 nTPM
GTEx:919.4 nTPM
FANTOM5:277.0 Scaled Tags Per Million
Pig:73.2 nTPM
Mouse:258.8 nTPM
Allen mouse:4.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

222.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 194.7
2666 Male, age 74, left hemisphere 241.4
2411 Female, age 72, unknown 209.2
1870 Female, age 42, unknown 204.9
2828 Female, age 72, unknown 194.2
2019 Male, age 18, unknown 194.0
1827 Male, age 72, unknown 191.2
1833 Male, age 53, unknown 189.1
1830 Male, age 51, unknown 182.3
2586 Male, age 75, left hemisphere 174.1
2219 Male, age 76, both hemispheres 166.4
Dorsal raphe nucleus
nTPM: 195.4
2298 Female, age 72, unknown 218.1
1828 Male, age 53, unknown 201.9
2016 Female, age 72, unknown 193.2
2750 Male, age 76, both hemispheres 186.3
2047 Male, age 72, unknown 177.4
Inferior colliculus
nTPM: 190.2
2849 Male, age 72, unknown 197.8
1890 Male, age 53, unknown 193.3
2097 Female, age 72, unknown 191.5
1848 Female, age 42, unknown 178.0
Median raphe nucleus
nTPM: 193.6
2220 Male, age 76, midline 193.6
Periaquaductal grey, anterior
nTPM: 202.4
2502 Female, age 75, unknown 218.5
1947 Male, age 18, unknown 198.8
1795 Male, age 51, unknown 189.8
Periaquaductal grey, dorsal
nTPM: 199.2
1840 Male, age 53, unknown 232.6
2850 Male, age 76, both hemispheres 207.4
2464 Female, age 72, unknown 179.1
1831 Male, age 72, unknown 177.9
Periaquaductal grey, lateral
nTPM: 187.5
2140 Male, age 76, both hemispheres 202.6
2053 Male, age 18, unknown 184.9
2272 Male, age 74, both hemispheres 175.1
Pretectal area
nTPM: 189.9
1817 Female, age 42, unknown 206.7
2825 Male, age 18, unknown 204.0
1815 Male, age 53, unknown 198.2
2007 Male, age 72, unknown 196.5
1944 Female, age 72, unknown 196.1
2224 Female, age 72, unknown 194.8
1816 Male, age 51, unknown 189.2
2273 Male, age 74, both hemispheres 182.8
2316 Male, age 76, right hemisphere 181.3
2667 Female, age 75, unknown 171.1
2407 Male, age 75, both hemispheres 168.7
Red nucleus
nTPM: 216.4
2503 Female, age 72, unknown 268.7
2725 Female, age 75, unknown 253.6
1865 Male, age 51, unknown 232.5
2588 Male, age 74, left hemisphere 227.6
1821 Female, age 72, unknown 221.5
1904 Male, age 53, unknown 216.8
2227 Male, age 72, unknown 209.9
2769 Male, age 72, unknown 208.2
1954 Female, age 42, unknown 202.3
2584 Male, age 75, left hemisphere 194.5
2785 Male, age 18, unknown 194.2
2823 Male, age 76, right hemisphere 166.7
Substantia nigra
nTPM: 222.6
2409 Female, age 72, unknown 264.5
2241 Male, age 72, unknown 264.4
1851 Male, age 51, unknown 261.6
1916 Female, age 42, unknown 243.2
2665 Male, age 74, both hemispheres 235.7
2699 Male, age 18, unknown 232.5
1889 Female, age 72, unknown 195.4
2590 Female, age 75, unknown 188.3
1941 Male, age 53, unknown 180.2
2583 Male, age 75, right hemisphere 160.5
Superior colliculus
nTPM: 194.0
2587 Male, age 74, left hemisphere 253.1
1913 Female, age 42, unknown 206.2
2668 Female, age 75, unknown 195.0
1995 Male, age 72, unknown 194.0
2261 Male, age 18, unknown 192.3
1796 Male, age 53, unknown 190.5
2087 Female, age 72, unknown 182.4
1839 Male, age 51, unknown 181.9
1895 Male, age 76, right hemisphere 174.4
2664 Male, age 75, both hemispheres 170.4
Ventral tegmental area
nTPM: 208.1
1915 Female, age 42, unknown 238.7
2223 Female, age 72, unknown 226.0
2410 Female, age 72, unknown 205.2
2021 Male, age 53, unknown 200.5
1942 Male, age 51, unknown 193.0
2218 Male, age 76, both hemispheres 185.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

919.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 919.4
Samples: 139

Max nTPM: 3344.1
Min nTPM: 390.0
Std nTPM: 393.7
Median nTPM: 813.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 3344.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2435.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 2188.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 2049.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1750.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1643.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1568.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1564.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1551.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1517.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1399.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1360.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1328.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1318.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1311.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1309.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1276.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1235.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1208.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1182.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1181.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1174.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1172.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1170.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1167.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1165.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1164.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1149.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1148.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1126.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1105.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1100.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1085.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1079.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1079.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1072.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1070.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1054.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1043.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1041.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1019.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1019.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1016.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1016.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 993.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 968.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 961.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 954.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 954.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 953.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 929.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 927.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 921.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 901.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 897.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 895.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 893.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 885.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 870.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 861.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 852.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 852.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 844.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 844.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 843.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 833.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 833.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 820.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 815.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 813.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 808.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 804.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 800.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 800.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 798.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 797.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 796.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 785.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 782.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 779.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 770.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 762.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 759.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 755.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 753.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 749.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 748.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 748.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 747.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 747.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 741.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 729.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 729.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 727.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 720.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 719.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 714.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 713.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 712.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 693.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 685.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 682.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 681.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 675.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 673.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 670.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 669.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 663.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 653.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 647.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 647.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 641.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 634.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 632.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 622.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 617.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 608.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 607.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 600.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 599.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 584.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 584.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 582.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 581.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 573.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 569.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 569.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 565.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 555.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 553.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 548.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 537.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 536.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 526.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 505.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 456.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 445.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 427.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 390.0
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

277.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 277.0
FF:10158-103A5 76 years, female 277.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

73.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 64.3
Samples: 4

Max nTPM: 93.7
Min nTPM: 41.7
Sample A Female 93.7
Sample B Female 58.6
Sample C Male 63.0
Sample D Male 41.7
Midbrain
nTPM: 66.4
Samples: 4

Max nTPM: 78.8
Min nTPM: 58.7
Sample A Female 78.8
Sample B Female 64.1
Sample C Male 63.9
Sample D Male 58.7
Periaqueductal gray
nTPM: 49.5
Samples: 3

Max nTPM: 52.7
Min nTPM: 43.8
Sample B Female 52.0
Sample C Male 52.7
Sample D Male 43.8
Superior colliculi
nTPM: 73.2
Samples: 4

Max nTPM: 85.7
Min nTPM: 56.3
Sample A Female 85.7
Sample B Female 69.8
Sample C Male 80.8
Sample D Male 56.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

258.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 258.8
Samples: 4

Max nTPM: 293.5
Min nTPM: 234.3
Sample A Male 293.5
Sample B Male 248.9
Sample C Female 234.3
Sample D Female 258.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.8
68498271 Antisense, RP_050113_01_F04, Mouse strain C57BL/6J (56 days, male) 4.8

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The Human Protein Atlas

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


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