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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:2687.4 nTPM
HPA Brain:1855.3 nTPM
GTEx:2687.4 nTPM
FANTOM5:1566.9 Scaled Tags Per Million
Pig:1518.5 nTPM
Mouse:417.2 nTPM
Allen mouse:23.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1855.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 1297.7
2586 Male, age 75, left hemisphere 2215.7
2828 Female, age 72, unknown 1706.5
2219 Male, age 76, both hemispheres 1332.9
2666 Male, age 74, left hemisphere 1284.7
1833 Male, age 53, unknown 1247.6
1827 Male, age 72, unknown 1146.3
1870 Female, age 42, unknown 1129.8
1830 Male, age 51, unknown 1066.1
2411 Female, age 72, unknown 1061.4
2019 Male, age 18, unknown 786.2
Dorsal raphe nucleus
nTPM: 1608.3
2047 Male, age 72, unknown 1803.6
2298 Female, age 72, unknown 1757.5
2016 Female, age 72, unknown 1639.4
2750 Male, age 76, both hemispheres 1489.3
1828 Male, age 53, unknown 1351.6
Inferior colliculus
nTPM: 1241.8
1848 Female, age 42, unknown 1274.0
1890 Male, age 53, unknown 1254.3
2097 Female, age 72, unknown 1221.4
2849 Male, age 72, unknown 1217.6
Median raphe nucleus
nTPM: 1584.5
2220 Male, age 76, midline 1584.5
Periaquaductal grey, anterior
nTPM: 1473.9
1795 Male, age 51, unknown 1591.0
1947 Male, age 18, unknown 1458.5
2502 Female, age 75, unknown 1372.1
Periaquaductal grey, dorsal
nTPM: 1326.8
1840 Male, age 53, unknown 1734.8
2850 Male, age 76, both hemispheres 1371.8
2464 Female, age 72, unknown 1135.4
1831 Male, age 72, unknown 1065.2
Periaquaductal grey, lateral
nTPM: 1261.6
2140 Male, age 76, both hemispheres 1376.1
2272 Male, age 74, both hemispheres 1240.4
2053 Male, age 18, unknown 1168.3
Pretectal area
nTPM: 1218.8
2224 Female, age 72, unknown 1576.2
2825 Male, age 18, unknown 1498.4
1817 Female, age 42, unknown 1445.1
2007 Male, age 72, unknown 1215.2
1944 Female, age 72, unknown 1212.4
1815 Male, age 53, unknown 1195.4
2667 Female, age 75, unknown 1181.5
1816 Male, age 51, unknown 1153.7
2316 Male, age 76, right hemisphere 1123.2
2273 Male, age 74, both hemispheres 971.2
2407 Male, age 75, both hemispheres 834.3
Red nucleus
nTPM: 1434.4
2227 Male, age 72, unknown 1780.3
2769 Male, age 72, unknown 1763.3
2503 Female, age 72, unknown 1731.7
2584 Male, age 75, left hemisphere 1580.3
1954 Female, age 42, unknown 1497.4
2725 Female, age 75, unknown 1460.9
1904 Male, age 53, unknown 1455.3
2823 Male, age 76, right hemisphere 1416.5
1821 Female, age 72, unknown 1330.5
1865 Male, age 51, unknown 1287.8
2785 Male, age 18, unknown 955.2
2588 Male, age 74, left hemisphere 954.1
Substantia nigra
nTPM: 1855.3
2699 Male, age 18, unknown 3098.2
1916 Female, age 42, unknown 2664.8
1851 Male, age 51, unknown 2241.5
2665 Male, age 74, both hemispheres 1782.6
2590 Female, age 75, unknown 1612.9
2583 Male, age 75, right hemisphere 1579.6
2409 Female, age 72, unknown 1548.3
1889 Female, age 72, unknown 1495.0
2241 Male, age 72, unknown 1349.5
1941 Male, age 53, unknown 1181.0
Superior colliculus
nTPM: 1133.6
1796 Male, age 53, unknown 1468.3
2261 Male, age 18, unknown 1305.4
2668 Female, age 75, unknown 1290.8
2087 Female, age 72, unknown 1255.2
2664 Male, age 75, both hemispheres 1189.0
1995 Male, age 72, unknown 1104.7
1839 Male, age 51, unknown 985.3
2587 Male, age 74, left hemisphere 953.6
1913 Female, age 42, unknown 936.3
1895 Male, age 76, right hemisphere 847.1
Ventral tegmental area
nTPM: 1522.4
1915 Female, age 42, unknown 2020.4
1942 Male, age 51, unknown 1659.2
2218 Male, age 76, both hemispheres 1538.3
2021 Male, age 53, unknown 1466.9
2410 Female, age 72, unknown 1278.5
2223 Female, age 72, unknown 1171.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

2687.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 2687.4
Samples: 139

Max nTPM: 8735.8
Min nTPM: 142.5
Std nTPM: 1562.8
Median nTPM: 2553.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 8735.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 7620.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 7382.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 6747.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 6258.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 5733.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 5561.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 5328.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 5255.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 5253.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 5209.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 5189.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 5152.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 4937.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 4823.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 4732.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 4638.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 4555.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 4481.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 4382.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 4334.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 4275.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 4148.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 4117.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 4056.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 3938.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 3733.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 3709.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 3612.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 3548.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 3450.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 3423.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 3409.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 3390.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 3382.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 3334.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 3300.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 3287.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 3263.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 3240.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 3186.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 3134.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 3126.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 3092.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 3066.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 3013.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 2988.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 2982.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 2975.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 2944.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 2921.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 2920.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 2894.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 2891.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 2853.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 2848.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 2842.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 2810.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 2755.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 2728.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 2693.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 2668.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 2645.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 2631.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 2629.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 2624.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 2598.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 2577.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 2572.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 2553.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 2487.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 2419.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 2316.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 2291.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 2282.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 2218.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 2218.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 2175.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 2138.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 2133.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 2115.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 2104.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 2098.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 2088.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 2075.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 2028.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 2001.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1973.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1936.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 1902.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1900.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1883.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 1839.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1832.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1807.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1788.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1777.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 1775.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1708.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1693.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 1677.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 1671.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1649.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1609.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 1584.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 1563.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1535.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1525.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1524.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 1468.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1428.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1425.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1402.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1392.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1392.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1350.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1216.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1169.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 1147.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1129.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1100.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1082.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1063.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1017.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 964.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 867.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 816.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 804.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 756.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 713.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 693.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 641.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 539.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 525.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 479.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 475.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 468.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 401.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 142.5
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1566.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1566.9
FF:10158-103A5 76 years, female 1566.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1518.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 1497.1
Samples: 4

Max nTPM: 1732.5
Min nTPM: 1273.0
Sample A Female 1732.5
Sample B Female 1273.0
Sample C Male 1550.7
Sample D Male 1432.3
Midbrain
nTPM: 1493.4
Samples: 4

Max nTPM: 1881.5
Min nTPM: 1001.1
Sample A Female 1881.5
Sample B Female 1869.2
Sample C Male 1221.8
Sample D Male 1001.1
Periaqueductal gray
nTPM: 1518.5
Samples: 3

Max nTPM: 1662.0
Min nTPM: 1232.7
Sample B Female 1662.0
Sample C Male 1660.9
Sample D Male 1232.7
Superior colliculi
nTPM: 1144.4
Samples: 4

Max nTPM: 1397.1
Min nTPM: 759.8
Sample A Female 1397.1
Sample B Female 759.8
Sample C Male 1166.5
Sample D Male 1254.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

417.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 417.3
Samples: 4

Max nTPM: 569.8
Min nTPM: 318.5
Sample A Male 569.8
Sample B Male 393.1
Sample C Female 318.5
Sample D Female 387.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

23.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 23.2
67936406 Antisense, RP_040604_02_C10, Mouse strain C57BL/6J (56 days, male) 28.0
77620395 Antisense, RP_070205_01_F04, Mouse strain C57BL/6J (56 days, male) 18.4
79490110 Antisense, RP_070205_01_F04, Mouse strain C57BL/6J (56 days, male) 15.5

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