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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:7466.5 nTPM
HPA Brain:16300.7 nTPM
GTEx:7466.5 nTPM
FANTOM5:5108.1 Scaled Tags Per Million
Pig:6691.7 nTPM
Mouse:243.7 nTPM
Allen mouse:2.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

16300.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 7916.9
2828 Female, age 72, unknown 14487.4
2666 Male, age 74, left hemisphere 10836.5
2586 Male, age 75, left hemisphere 9493.7
1870 Female, age 42, unknown 9074.5
1827 Male, age 72, unknown 8934.8
2411 Female, age 72, unknown 7512.5
1833 Male, age 53, unknown 6244.8
1830 Male, age 51, unknown 5728.4
2219 Male, age 76, both hemispheres 3740.6
2019 Male, age 18, unknown 3115.2
Dorsal raphe nucleus
nTPM: 12127.0
2016 Female, age 72, unknown 18299.6
2298 Female, age 72, unknown 12752.5
2047 Male, age 72, unknown 12290.6
1828 Male, age 53, unknown 11843.9
2750 Male, age 76, both hemispheres 5448.5
Inferior colliculus
nTPM: 9642.2
2849 Male, age 72, unknown 11122.2
2097 Female, age 72, unknown 10022.9
1848 Female, age 42, unknown 9838.2
1890 Male, age 53, unknown 7585.6
Median raphe nucleus
nTPM: 6760.7
2220 Male, age 76, midline 6760.7
Periaquaductal grey, anterior
nTPM: 10003.2
1795 Male, age 51, unknown 13195.1
2502 Female, age 75, unknown 9613.4
1947 Male, age 18, unknown 7201.0
Periaquaductal grey, dorsal
nTPM: 13838.3
1840 Male, age 53, unknown 16070.3
2850 Male, age 76, both hemispheres 14914.4
1831 Male, age 72, unknown 13189.5
2464 Female, age 72, unknown 11178.9
Periaquaductal grey, lateral
nTPM: 16300.7
2053 Male, age 18, unknown 25346.5
2140 Male, age 76, both hemispheres 14542.4
2272 Male, age 74, both hemispheres 9013.2
Pretectal area
nTPM: 7974.5
2825 Male, age 18, unknown 14188.3
2273 Male, age 74, both hemispheres 11560.7
2224 Female, age 72, unknown 9780.7
2316 Male, age 76, right hemisphere 9298.4
2407 Male, age 75, both hemispheres 8399.9
1944 Female, age 72, unknown 7832.7
2667 Female, age 75, unknown 6662.5
1815 Male, age 53, unknown 6511.3
1816 Male, age 51, unknown 5274.6
1817 Female, age 42, unknown 4445.8
2007 Male, age 72, unknown 3765.1
Red nucleus
nTPM: 6259.6
2503 Female, age 72, unknown 10487.4
2725 Female, age 75, unknown 7489.2
2769 Male, age 72, unknown 7360.9
2227 Male, age 72, unknown 6918.6
2823 Male, age 76, right hemisphere 6051.1
1821 Female, age 72, unknown 5948.5
2584 Male, age 75, left hemisphere 5629.9
2588 Male, age 74, left hemisphere 5514.4
1865 Male, age 51, unknown 5474.2
1954 Female, age 42, unknown 5401.4
1904 Male, age 53, unknown 5147.6
2785 Male, age 18, unknown 3692.3
Substantia nigra
nTPM: 7137.2
2699 Male, age 18, unknown 13354.8
1851 Male, age 51, unknown 7893.6
2590 Female, age 75, unknown 7631.4
2583 Male, age 75, right hemisphere 6906.4
1941 Male, age 53, unknown 6680.4
2665 Male, age 74, both hemispheres 6521.7
1916 Female, age 42, unknown 6273.4
1889 Female, age 72, unknown 5853.4
2409 Female, age 72, unknown 5846.9
2241 Male, age 72, unknown 4410.6
Superior colliculus
nTPM: 9737.5
1995 Male, age 72, unknown 13782.9
1913 Female, age 42, unknown 13035.4
2664 Male, age 75, both hemispheres 11647.2
1796 Male, age 53, unknown 11121.2
2587 Male, age 74, left hemisphere 9748.0
1839 Male, age 51, unknown 9175.6
2087 Female, age 72, unknown 8469.1
2668 Female, age 75, unknown 7679.2
2261 Male, age 18, unknown 7598.9
1895 Male, age 76, right hemisphere 5118.0
Ventral tegmental area
nTPM: 9932.8
2021 Male, age 53, unknown 13143.9
1915 Female, age 42, unknown 12584.0
1942 Male, age 51, unknown 12230.3
2223 Female, age 72, unknown 7606.4
2410 Female, age 72, unknown 7426.8
2218 Male, age 76, both hemispheres 6605.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

7466.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 7466.5
Samples: 139

Max nTPM: 24349.4
Min nTPM: 1586.3
Std nTPM: 4100.1
Median nTPM: 6713.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 24349.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 19596.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 19021.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 18916.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 18492.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 15726.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 14961.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 14423.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 14385.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 13830.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 13825.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 13738.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 13498.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 13248.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 13129.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 12936.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 12244.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 12056.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 11874.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 11846.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 11717.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 11636.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 11481.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 11338.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 11217.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 10845.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 10748.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 10718.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 10469.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 10437.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 10352.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 10278.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 10266.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 9436.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 9208.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 9198.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 9031.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 8766.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 8754.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 8671.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 8581.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 8520.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 8469.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 8424.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 8422.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 8386.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 8271.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 8196.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 8180.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 7946.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 7822.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 7752.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 7689.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 7687.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 7681.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 7618.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 7485.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 7404.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 7308.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 7137.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 7077.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 7030.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 6997.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 6993.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 6975.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 6856.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 6789.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 6754.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 6741.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 6713.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 6678.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 6538.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 6330.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 6141.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 6116.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 6067.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 6028.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 5989.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 5968.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 5964.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 5890.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 5839.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 5829.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 5823.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 5786.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 5674.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 5647.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 5471.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 5447.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 5403.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 5383.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 5376.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 5364.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 5351.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 5295.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 5201.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 5164.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 5073.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 4969.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 4939.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 4850.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 4716.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 4667.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 4651.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 4544.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 4503.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 4317.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 4310.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 4273.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 4259.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 4137.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 4114.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 4064.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 3907.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 3801.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 3786.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 3693.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 3685.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 3627.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 3604.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 3496.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 3284.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 3203.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 3125.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 3071.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 2929.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 2835.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 2548.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 2535.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2519.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 2476.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 2346.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 2327.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 2321.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 2313.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 2227.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 2039.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1794.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1586.3
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

5108.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 5108.1
FF:10158-103A5 76 years, female 5108.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

6691.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 6008.9
Samples: 4

Max nTPM: 6363.8
Min nTPM: 5659.0
Sample A Female 6363.8
Sample B Female 5659.0
Sample C Male 6013.5
Sample D Male 5999.1
Midbrain
nTPM: 6691.7
Samples: 4

Max nTPM: 15487.7
Min nTPM: 2336.7
Sample A Female 15487.7
Sample B Female 5116.1
Sample C Male 3826.3
Sample D Male 2336.7
Periaqueductal gray
nTPM: 6289.9
Samples: 3

Max nTPM: 7743.1
Min nTPM: 5550.9
Sample B Female 5550.9
Sample C Male 7743.1
Sample D Male 5575.8
Superior colliculi
nTPM: 3466.1
Samples: 4

Max nTPM: 4175.9
Min nTPM: 2032.6
Sample A Female 3533.8
Sample B Female 2032.6
Sample C Male 4122.1
Sample D Male 4175.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

243.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 243.7
Samples: 4

Max nTPM: 269.4
Min nTPM: 221.0
Sample A Male 269.4
Sample B Male 227.5
Sample C Female 221.0
Sample D Female 256.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.7
1358 Antisense, RP_Baylor_253913, Mouse strain C57BL/6J (56 days, male) 2.8
79591671 Antisense, RP_071204_04_G06, Mouse strain C57BL/6J (56 days, male) 2.7
1357 Antisense, RP_Baylor_253913, Mouse strain C57BL/6J (56 days, male) 2.6
79913385 Antisense, RP_071204_04_G06, Mouse strain C57BL/6J (56 days, male) 2.0

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