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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:263.0 nTPM
HPA Brain:666.4 nTPM
GTEx:263.0 nTPM
FANTOM5:385.0 Scaled Tags Per Million
Pig:142.1 nTPM
Mouse:69.7 nTPM
Allen mouse:7.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

666.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 534.1
2828 Female, age 72, unknown 778.1
2586 Male, age 75, left hemisphere 772.6
2219 Male, age 76, both hemispheres 627.4
2666 Male, age 74, left hemisphere 622.5
1827 Male, age 72, unknown 501.1
1833 Male, age 53, unknown 445.6
1870 Female, age 42, unknown 439.2
1830 Male, age 51, unknown 407.0
2019 Male, age 18, unknown 406.4
2411 Female, age 72, unknown 340.7
Dorsal raphe nucleus
nTPM: 526.8
2016 Female, age 72, unknown 681.6
1828 Male, age 53, unknown 594.1
2047 Male, age 72, unknown 515.7
2298 Female, age 72, unknown 448.1
2750 Male, age 76, both hemispheres 394.4
Inferior colliculus
nTPM: 467.1
2849 Male, age 72, unknown 568.9
1848 Female, age 42, unknown 477.8
1890 Male, age 53, unknown 460.3
2097 Female, age 72, unknown 361.3
Median raphe nucleus
nTPM: 399.5
2220 Male, age 76, midline 399.5
Periaquaductal grey, anterior
nTPM: 569.1
1795 Male, age 51, unknown 699.6
2502 Female, age 75, unknown 587.7
1947 Male, age 18, unknown 419.8
Periaquaductal grey, dorsal
nTPM: 638.4
2850 Male, age 76, both hemispheres 801.2
1831 Male, age 72, unknown 692.6
1840 Male, age 53, unknown 613.0
2464 Female, age 72, unknown 447.0
Periaquaductal grey, lateral
nTPM: 666.4
2053 Male, age 18, unknown 745.5
2140 Male, age 76, both hemispheres 740.5
2272 Male, age 74, both hemispheres 513.2
Pretectal area
nTPM: 577.7
2316 Male, age 76, right hemisphere 659.7
2407 Male, age 75, both hemispheres 651.8
2825 Male, age 18, unknown 616.8
2667 Female, age 75, unknown 615.6
1815 Male, age 53, unknown 588.3
1944 Female, age 72, unknown 580.8
1816 Male, age 51, unknown 567.3
2273 Male, age 74, both hemispheres 550.1
2224 Female, age 72, unknown 533.1
1817 Female, age 42, unknown 512.3
2007 Male, age 72, unknown 478.3
Red nucleus
nTPM: 494.6
2769 Male, age 72, unknown 545.0
2503 Female, age 72, unknown 544.0
2584 Male, age 75, left hemisphere 526.5
2823 Male, age 76, right hemisphere 520.5
2588 Male, age 74, left hemisphere 518.4
2227 Male, age 72, unknown 501.9
1904 Male, age 53, unknown 497.4
1865 Male, age 51, unknown 493.6
2785 Male, age 18, unknown 467.9
1954 Female, age 42, unknown 447.2
2725 Female, age 75, unknown 446.0
1821 Female, age 72, unknown 426.5
Substantia nigra
nTPM: 542.2
2699 Male, age 18, unknown 870.6
2665 Male, age 74, both hemispheres 703.4
2583 Male, age 75, right hemisphere 632.6
1916 Female, age 42, unknown 547.3
1851 Male, age 51, unknown 527.0
2590 Female, age 75, unknown 471.4
1889 Female, age 72, unknown 457.5
1941 Male, age 53, unknown 451.4
2409 Female, age 72, unknown 415.6
2241 Male, age 72, unknown 345.5
Superior colliculus
nTPM: 586.6
2664 Male, age 75, both hemispheres 851.8
1995 Male, age 72, unknown 698.1
2668 Female, age 75, unknown 623.0
1913 Female, age 42, unknown 620.8
1796 Male, age 53, unknown 581.7
2587 Male, age 74, left hemisphere 552.6
2087 Female, age 72, unknown 550.4
1839 Male, age 51, unknown 543.6
2261 Male, age 18, unknown 501.0
1895 Male, age 76, right hemisphere 343.2
Ventral tegmental area
nTPM: 516.9
2021 Male, age 53, unknown 585.1
1942 Male, age 51, unknown 549.8
1915 Female, age 42, unknown 532.3
2218 Male, age 76, both hemispheres 487.6
2223 Female, age 72, unknown 478.4
2410 Female, age 72, unknown 468.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

263.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 263.0
Samples: 139

Max nTPM: 481.4
Min nTPM: 69.3
Std nTPM: 89.4
Median nTPM: 252.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 481.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 475.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 471.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 469.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 434.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 424.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 423.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 415.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 414.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 414.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 406.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 404.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 402.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 393.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 389.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 387.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 386.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 382.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 376.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 375.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 366.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 366.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 359.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 351.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 347.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 343.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 342.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 341.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 336.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 335.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 334.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 333.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 331.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 330.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 328.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 327.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 324.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 324.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 321.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 321.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 315.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 313.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 307.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 300.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 300.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 299.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 299.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 296.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 288.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 288.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 284.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 279.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 277.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 273.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 270.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 269.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 268.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 267.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 266.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 265.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 264.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 262.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 258.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 257.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 256.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 255.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 254.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 254.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 252.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 252.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 252.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 248.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 247.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 246.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 245.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 244.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 239.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 237.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 236.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 235.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 234.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 233.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 232.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 231.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 230.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 228.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 228.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 226.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 224.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 222.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 222.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 220.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 216.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 214.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 211.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 210.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 209.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 209.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 207.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 205.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 202.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 201.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 200.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 199.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 195.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 191.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 189.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 188.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 186.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 184.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 183.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 182.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 181.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 180.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 177.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 177.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 177.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 176.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 174.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 173.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 170.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 169.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 166.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 166.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 163.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 162.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 159.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 156.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 146.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 141.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 136.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 135.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 113.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 113.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 112.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 106.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 104.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 83.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 69.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

385.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 385.0
FF:10158-103A5 76 years, female 385.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

142.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 142.1
Samples: 4

Max nTPM: 158.5
Min nTPM: 117.4
Sample A Female 135.9
Sample B Female 117.4
Sample C Male 158.5
Sample D Male 156.5
Midbrain
nTPM: 136.1
Samples: 4

Max nTPM: 144.1
Min nTPM: 123.8
Sample A Female 123.8
Sample B Female 137.9
Sample C Male 144.1
Sample D Male 138.4
Periaqueductal gray
nTPM: 140.1
Samples: 3

Max nTPM: 148.7
Min nTPM: 127.1
Sample B Female 144.5
Sample C Male 148.7
Sample D Male 127.1
Superior colliculi
nTPM: 127.8
Samples: 4

Max nTPM: 156.3
Min nTPM: 78.2
Sample A Female 138.2
Sample B Female 78.2
Sample C Male 138.3
Sample D Male 156.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

69.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 69.7
Samples: 4

Max nTPM: 81.0
Min nTPM: 63.9
Sample A Male 81.0
Sample B Male 64.1
Sample C Female 63.9
Sample D Female 69.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

7.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.0
69816494 Antisense, RP_050510_01_C01, Mouse strain C57BL/6J (56 days, male) 7.1
77332715 Antisense, RP_070116_02_B11, Mouse strain C57BL/6J (56 days, male) 6.9

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