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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:829.5 nTPM
HPA Brain:178.4 nTPM
GTEx:829.5 nTPM
FANTOM5:31.1 Scaled Tags Per Million
Pig:101.6 nTPM
Mouse:294.4 nTPM
Allen mouse:4.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

178.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 150.0
1870 Female, age 42, unknown 187.8
2586 Male, age 75, left hemisphere 171.9
2666 Male, age 74, left hemisphere 155.5
2219 Male, age 76, both hemispheres 153.0
1833 Male, age 53, unknown 151.4
2828 Female, age 72, unknown 146.8
2019 Male, age 18, unknown 145.8
1830 Male, age 51, unknown 141.1
2411 Female, age 72, unknown 127.2
1827 Male, age 72, unknown 119.8
Dorsal raphe nucleus
nTPM: 162.4
2298 Female, age 72, unknown 194.6
2016 Female, age 72, unknown 180.3
2750 Male, age 76, both hemispheres 163.4
1828 Male, age 53, unknown 153.1
2047 Male, age 72, unknown 120.6
Inferior colliculus
nTPM: 154.4
1890 Male, age 53, unknown 174.8
2849 Male, age 72, unknown 154.6
2097 Female, age 72, unknown 147.0
1848 Female, age 42, unknown 141.3
Median raphe nucleus
nTPM: 161.9
2220 Male, age 76, midline 161.9
Periaquaductal grey, anterior
nTPM: 160.3
2502 Female, age 75, unknown 190.4
1947 Male, age 18, unknown 147.6
1795 Male, age 51, unknown 142.7
Periaquaductal grey, dorsal
nTPM: 154.2
2850 Male, age 76, both hemispheres 175.4
1831 Male, age 72, unknown 160.5
1840 Male, age 53, unknown 159.3
2464 Female, age 72, unknown 121.7
Periaquaductal grey, lateral
nTPM: 148.8
2053 Male, age 18, unknown 164.9
2140 Male, age 76, both hemispheres 153.9
2272 Male, age 74, both hemispheres 127.7
Pretectal area
nTPM: 147.4
2224 Female, age 72, unknown 184.1
2316 Male, age 76, right hemisphere 169.2
1815 Male, age 53, unknown 152.3
2825 Male, age 18, unknown 151.9
1817 Female, age 42, unknown 150.9
1816 Male, age 51, unknown 141.0
2007 Male, age 72, unknown 137.3
2667 Female, age 75, unknown 136.2
1944 Female, age 72, unknown 134.5
2273 Male, age 74, both hemispheres 132.7
2407 Male, age 75, both hemispheres 130.6
Red nucleus
nTPM: 172.4
2503 Female, age 72, unknown 228.2
1865 Male, age 51, unknown 212.4
1904 Male, age 53, unknown 184.4
1821 Female, age 72, unknown 184.3
2725 Female, age 75, unknown 179.2
2769 Male, age 72, unknown 172.0
2227 Male, age 72, unknown 167.1
1954 Female, age 42, unknown 157.4
2785 Male, age 18, unknown 156.5
2584 Male, age 75, left hemisphere 146.8
2588 Male, age 74, left hemisphere 141.9
2823 Male, age 76, right hemisphere 138.3
Substantia nigra
nTPM: 178.4
2241 Male, age 72, unknown 249.2
2699 Male, age 18, unknown 220.3
1851 Male, age 51, unknown 196.7
2409 Female, age 72, unknown 193.5
2665 Male, age 74, both hemispheres 186.9
1916 Female, age 42, unknown 170.4
2590 Female, age 75, unknown 155.9
1889 Female, age 72, unknown 154.4
1941 Male, age 53, unknown 130.9
2583 Male, age 75, right hemisphere 125.6
Superior colliculus
nTPM: 157.0
1913 Female, age 42, unknown 185.8
1995 Male, age 72, unknown 184.2
2587 Male, age 74, left hemisphere 174.6
1796 Male, age 53, unknown 166.1
2664 Male, age 75, both hemispheres 151.4
1895 Male, age 76, right hemisphere 150.5
2668 Female, age 75, unknown 149.1
1839 Male, age 51, unknown 148.1
2087 Female, age 72, unknown 132.2
2261 Male, age 18, unknown 128.0
Ventral tegmental area
nTPM: 168.4
2223 Female, age 72, unknown 198.0
1915 Female, age 42, unknown 192.1
2021 Male, age 53, unknown 162.2
2218 Male, age 76, both hemispheres 159.8
1942 Male, age 51, unknown 153.1
2410 Female, age 72, unknown 145.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

829.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 829.5
Samples: 139

Max nTPM: 2234.7
Min nTPM: 268.6
Std nTPM: 337.6
Median nTPM: 750.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 2234.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 2123.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2044.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1840.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1621.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1511.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1503.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1401.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1397.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1381.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1365.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1276.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1263.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1254.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1249.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1227.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1183.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1146.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1120.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1120.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1104.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1096.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1045.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1036.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1026.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1020.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1011.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 998.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 994.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 992.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 991.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 987.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 987.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 975.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 962.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 951.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 947.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 944.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 942.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 933.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 927.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 926.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 921.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 920.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 918.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 917.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 913.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 906.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 905.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 893.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 891.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 889.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 865.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 864.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 862.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 856.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 850.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 847.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 845.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 831.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 826.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 825.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 820.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 817.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 815.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 811.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 792.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 778.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 753.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 750.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 750.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 742.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 742.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 737.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 735.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 726.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 711.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 707.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 705.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 705.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 702.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 699.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 698.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 697.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 688.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 682.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 681.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 677.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 664.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 664.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 655.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 645.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 641.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 639.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 638.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 631.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 629.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 628.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 619.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 608.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 604.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 604.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 602.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 600.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 596.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 583.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 570.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 567.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 562.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 562.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 559.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 556.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 551.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 551.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 539.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 537.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 533.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 529.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 522.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 521.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 520.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 519.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 511.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 509.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 507.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 505.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 502.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 498.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 480.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 473.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 460.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 436.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 430.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 424.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 418.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 398.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 386.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 374.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 268.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

31.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 31.1
FF:10158-103A5 76 years, female 31.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

101.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 101.6
Samples: 4

Max nTPM: 130.4
Min nTPM: 78.5
Sample A Female 130.4
Sample B Female 106.3
Sample C Male 91.3
Sample D Male 78.5
Midbrain
nTPM: 93.6
Samples: 4

Max nTPM: 118.9
Min nTPM: 63.2
Sample A Female 118.9
Sample B Female 106.0
Sample C Male 86.1
Sample D Male 63.2
Periaqueductal gray
nTPM: 84.5
Samples: 3

Max nTPM: 93.5
Min nTPM: 75.8
Sample B Female 84.1
Sample C Male 93.5
Sample D Male 75.8
Superior colliculi
nTPM: 91.3
Samples: 4

Max nTPM: 103.6
Min nTPM: 71.5
Sample A Female 103.6
Sample B Female 71.5
Sample C Male 102.6
Sample D Male 87.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

294.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 294.4
Samples: 4

Max nTPM: 318.9
Min nTPM: 273.1
Sample A Male 318.9
Sample B Male 291.1
Sample C Female 273.1
Sample D Female 294.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.4
68862012 Antisense, RP_050301_01_C11, Mouse strain C57BL/6J (56 days, male) 4.7
74357560 Antisense, RP_051214_01_B11, Mouse strain C57BL/6J (56 days, male) 4.1

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