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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:340.7 nTPM
HPA Brain:549.2 nTPM
GTEx:340.7 nTPM
FANTOM5:702.8 Scaled Tags Per Million
Pig:769.5 nTPM
Mouse:1419.2 nTPM
Allen mouse:22.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

549.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 438.6
2019 Male, age 18, unknown 637.0
2411 Female, age 72, unknown 612.7
1827 Male, age 72, unknown 489.4
2219 Male, age 76, both hemispheres 445.5
1870 Female, age 42, unknown 405.5
1833 Male, age 53, unknown 404.3
2666 Male, age 74, left hemisphere 385.2
1830 Male, age 51, unknown 382.9
2828 Female, age 72, unknown 372.7
2586 Male, age 75, left hemisphere 250.4
Dorsal raphe nucleus
nTPM: 402.0
1828 Male, age 53, unknown 475.1
2750 Male, age 76, both hemispheres 444.0
2298 Female, age 72, unknown 440.8
2047 Male, age 72, unknown 371.0
2016 Female, age 72, unknown 279.0
Inferior colliculus
nTPM: 440.1
2097 Female, age 72, unknown 548.4
1848 Female, age 42, unknown 466.2
1890 Male, age 53, unknown 439.5
2849 Male, age 72, unknown 306.5
Median raphe nucleus
nTPM: 427.5
2220 Male, age 76, midline 427.5
Periaquaductal grey, anterior
nTPM: 400.1
1947 Male, age 18, unknown 460.3
1795 Male, age 51, unknown 375.5
2502 Female, age 75, unknown 364.4
Periaquaductal grey, dorsal
nTPM: 285.1
1831 Male, age 72, unknown 348.9
2464 Female, age 72, unknown 323.0
1840 Male, age 53, unknown 237.3
2850 Male, age 76, both hemispheres 231.3
Periaquaductal grey, lateral
nTPM: 333.1
2272 Male, age 74, both hemispheres 475.2
2053 Male, age 18, unknown 322.6
2140 Male, age 76, both hemispheres 201.5
Pretectal area
nTPM: 504.4
2007 Male, age 72, unknown 731.8
1817 Female, age 42, unknown 720.1
1944 Female, age 72, unknown 686.3
1816 Male, age 51, unknown 679.6
1815 Male, age 53, unknown 571.8
2273 Male, age 74, both hemispheres 456.0
2667 Female, age 75, unknown 380.6
2224 Female, age 72, unknown 349.2
2407 Male, age 75, both hemispheres 346.8
2825 Male, age 18, unknown 316.6
2316 Male, age 76, right hemisphere 309.9
Red nucleus
nTPM: 544.7
1821 Female, age 72, unknown 843.1
1865 Male, age 51, unknown 587.5
1954 Female, age 42, unknown 581.4
2725 Female, age 75, unknown 544.5
2785 Male, age 18, unknown 544.0
2823 Male, age 76, right hemisphere 514.2
1904 Male, age 53, unknown 506.7
2769 Male, age 72, unknown 495.7
2227 Male, age 72, unknown 494.6
2503 Female, age 72, unknown 484.0
2588 Male, age 74, left hemisphere 472.5
2584 Male, age 75, left hemisphere 467.7
Substantia nigra
nTPM: 549.2
1941 Male, age 53, unknown 785.5
1889 Female, age 72, unknown 727.5
1916 Female, age 42, unknown 713.9
1851 Male, age 51, unknown 559.2
2241 Male, age 72, unknown 553.7
2409 Female, age 72, unknown 542.3
2590 Female, age 75, unknown 458.8
2583 Male, age 75, right hemisphere 417.7
2699 Male, age 18, unknown 394.5
2665 Male, age 74, both hemispheres 338.3
Superior colliculus
nTPM: 444.0
2668 Female, age 75, unknown 661.4
2087 Female, age 72, unknown 591.8
1895 Male, age 76, right hemisphere 550.2
2587 Male, age 74, left hemisphere 487.9
2261 Male, age 18, unknown 475.4
1796 Male, age 53, unknown 386.9
1913 Female, age 42, unknown 375.7
1839 Male, age 51, unknown 373.3
1995 Male, age 72, unknown 325.7
2664 Male, age 75, both hemispheres 211.5
Ventral tegmental area
nTPM: 461.8
2410 Female, age 72, unknown 681.6
2218 Male, age 76, both hemispheres 552.6
1915 Female, age 42, unknown 491.3
2223 Female, age 72, unknown 390.5
1942 Male, age 51, unknown 360.9
2021 Male, age 53, unknown 294.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

340.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 340.7
Samples: 139

Max nTPM: 1875.1
Min nTPM: 38.1
Std nTPM: 271.0
Median nTPM: 275.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1875.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 1447.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1153.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1012.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 995.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 865.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 797.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 720.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 700.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 695.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 677.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 671.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 667.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 658.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 633.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 631.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 630.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 607.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 606.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 601.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 593.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 576.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 571.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 555.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 554.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 552.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 544.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 539.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 502.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 490.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 488.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 487.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 485.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 475.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 450.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 447.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 439.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 422.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 420.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 406.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 403.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 394.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 393.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 386.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 382.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 369.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 367.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 367.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 361.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 359.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 352.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 350.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 343.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 340.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 335.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 335.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 333.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 326.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 324.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 320.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 317.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 315.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 313.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 302.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 302.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 300.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 295.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 282.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 279.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 275.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 275.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 266.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 265.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 260.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 258.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 258.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 257.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 244.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 238.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 231.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 227.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 220.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 219.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 215.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 213.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 213.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 210.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 205.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 204.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 202.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 194.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 186.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 175.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 175.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 169.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 168.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 167.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 167.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 167.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 162.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 160.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 159.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 157.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 152.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 152.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 148.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 148.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 145.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 143.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 142.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 135.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 134.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 130.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 129.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 127.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 126.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 116.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 114.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 112.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 111.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 108.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 104.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 96.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 96.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 95.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 93.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 92.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 86.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 74.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 72.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 72.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 68.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 62.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 58.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 52.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 51.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 45.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 40.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 38.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

702.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 702.8
FF:10158-103A5 76 years, female 702.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

769.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 421.2
Samples: 4

Max nTPM: 641.5
Min nTPM: 200.9
Sample A Female 641.5
Sample B Female 291.5
Sample C Male 550.7
Sample D Male 200.9
Midbrain
nTPM: 570.0
Samples: 4

Max nTPM: 916.6
Min nTPM: 229.8
Sample A Female 229.8
Sample B Female 336.2
Sample C Male 797.2
Sample D Male 916.6
Periaqueductal gray
nTPM: 330.3
Samples: 3

Max nTPM: 388.9
Min nTPM: 271.6
Sample B Female 330.3
Sample C Male 388.9
Sample D Male 271.6
Superior colliculi
nTPM: 769.5
Samples: 4

Max nTPM: 1018.7
Min nTPM: 424.1
Sample A Female 978.8
Sample B Female 424.1
Sample C Male 1018.7
Sample D Male 656.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1419.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 1419.2
Samples: 4

Max nTPM: 1489.1
Min nTPM: 1318.5
Sample A Male 1318.5
Sample B Male 1461.3
Sample C Female 1489.1
Sample D Female 1408.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

22.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 22.7
68546368 Antisense, RP_050120_02_D04, Mouse strain C57BL/6J (56 days, male) 25.4
70919203 Antisense, RP_050712_04_D08, Mouse strain C57BL/6J (56 days, male) 20.1

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