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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:1314.8 nTPM
HPA Brain:356.6 nTPM
GTEx:1314.8 nTPM
FANTOM5:22.6 Scaled Tags Per Million
Pig:510.3 nTPM
Mouse:785.1 nTPM
Allen mouse:15.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

356.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 302.9
2666 Male, age 74, left hemisphere 345.5
2411 Female, age 72, unknown 335.3
1870 Female, age 42, unknown 329.4
1827 Male, age 72, unknown 306.2
2828 Female, age 72, unknown 300.3
1830 Male, age 51, unknown 294.9
2586 Male, age 75, left hemisphere 283.3
2219 Male, age 76, both hemispheres 282.5
1833 Male, age 53, unknown 278.0
2019 Male, age 18, unknown 273.6
Dorsal raphe nucleus
nTPM: 324.2
2298 Female, age 72, unknown 409.3
2016 Female, age 72, unknown 360.0
2750 Male, age 76, both hemispheres 303.3
1828 Male, age 53, unknown 292.3
2047 Male, age 72, unknown 256.0
Inferior colliculus
nTPM: 320.8
1890 Male, age 53, unknown 346.4
2097 Female, age 72, unknown 342.1
2849 Male, age 72, unknown 299.3
1848 Female, age 42, unknown 295.4
Median raphe nucleus
nTPM: 289.8
2220 Male, age 76, midline 289.8
Periaquaductal grey, anterior
nTPM: 334.9
2502 Female, age 75, unknown 397.8
1947 Male, age 18, unknown 315.3
1795 Male, age 51, unknown 291.8
Periaquaductal grey, dorsal
nTPM: 322.8
1840 Male, age 53, unknown 388.6
2464 Female, age 72, unknown 314.8
1831 Male, age 72, unknown 303.2
2850 Male, age 76, both hemispheres 284.7
Periaquaductal grey, lateral
nTPM: 294.8
2140 Male, age 76, both hemispheres 307.1
2053 Male, age 18, unknown 304.7
2272 Male, age 74, both hemispheres 272.6
Pretectal area
nTPM: 294.2
2224 Female, age 72, unknown 343.4
2316 Male, age 76, right hemisphere 336.2
2825 Male, age 18, unknown 327.8
2273 Male, age 74, both hemispheres 308.6
1815 Male, age 53, unknown 301.6
2007 Male, age 72, unknown 285.0
1816 Male, age 51, unknown 283.0
1817 Female, age 42, unknown 275.8
1944 Female, age 72, unknown 263.1
2667 Female, age 75, unknown 258.4
2407 Male, age 75, both hemispheres 253.4
Red nucleus
nTPM: 329.5
2503 Female, age 72, unknown 429.2
1865 Male, age 51, unknown 362.6
1821 Female, age 72, unknown 352.2
2725 Female, age 75, unknown 345.9
1904 Male, age 53, unknown 335.5
2227 Male, age 72, unknown 330.3
2769 Male, age 72, unknown 317.4
2588 Male, age 74, left hemisphere 317.1
1954 Female, age 42, unknown 308.8
2584 Male, age 75, left hemisphere 303.5
2785 Male, age 18, unknown 291.9
2823 Male, age 76, right hemisphere 259.1
Substantia nigra
nTPM: 356.6
2241 Male, age 72, unknown 477.3
1851 Male, age 51, unknown 417.4
2665 Male, age 74, both hemispheres 399.2
2699 Male, age 18, unknown 392.1
2409 Female, age 72, unknown 364.9
1916 Female, age 42, unknown 353.1
2590 Female, age 75, unknown 327.7
1889 Female, age 72, unknown 290.4
1941 Male, age 53, unknown 285.9
2583 Male, age 75, right hemisphere 258.3
Superior colliculus
nTPM: 314.4
2587 Male, age 74, left hemisphere 370.5
1913 Female, age 42, unknown 348.8
1995 Male, age 72, unknown 335.6
1796 Male, age 53, unknown 322.5
2261 Male, age 18, unknown 314.6
2668 Female, age 75, unknown 299.6
1839 Male, age 51, unknown 299.4
1895 Male, age 76, right hemisphere 286.2
2664 Male, age 75, both hemispheres 286.2
2087 Female, age 72, unknown 280.1
Ventral tegmental area
nTPM: 342.2
1915 Female, age 42, unknown 388.7
2223 Female, age 72, unknown 364.7
2021 Male, age 53, unknown 347.7
2410 Female, age 72, unknown 340.8
1942 Male, age 51, unknown 325.4
2218 Male, age 76, both hemispheres 286.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1314.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1314.8
Samples: 139

Max nTPM: 3982.2
Min nTPM: 507.7
Std nTPM: 542.6
Median nTPM: 1197.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 3982.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 3485.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 3248.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2781.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 2705.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2394.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 2354.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2278.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 2162.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 2114.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 2107.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 2046.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 2041.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1941.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1931.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1847.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1812.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1808.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1808.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1791.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1765.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1751.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1687.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1675.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1672.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1649.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1640.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1633.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1629.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1603.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1597.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1573.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1551.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1527.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1519.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1489.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1486.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1474.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1452.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1437.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1419.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1414.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1402.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1383.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1381.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1380.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1380.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1372.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1372.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1348.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1342.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1336.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1332.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1322.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1314.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1307.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1297.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1279.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1269.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1266.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1253.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1247.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1247.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1241.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1239.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1236.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1222.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1218.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1211.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1197.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1192.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1184.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1169.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1167.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1161.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 1145.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1134.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1131.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1121.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1118.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 1114.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1097.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1097.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1093.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1087.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1078.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1065.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1058.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1056.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1053.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 1049.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1029.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1029.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1028.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1026.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1023.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1019.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1019.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1007.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 999.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 997.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 989.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 987.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 983.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 968.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 966.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 943.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 943.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 930.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 920.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 914.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 911.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 907.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 904.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 892.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 858.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 856.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 850.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 824.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 817.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 815.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 810.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 810.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 808.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 798.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 797.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 792.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 791.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 781.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 776.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 760.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 760.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 746.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 705.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 695.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 695.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 677.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 594.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 507.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

22.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 22.6
FF:10158-103A5 76 years, female 22.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

510.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 477.9
Samples: 4

Max nTPM: 632.4
Min nTPM: 360.8
Sample A Female 632.4
Sample B Female 542.3
Sample C Male 375.9
Sample D Male 360.8
Midbrain
nTPM: 457.2
Samples: 4

Max nTPM: 584.0
Min nTPM: 361.6
Sample A Female 584.0
Sample B Female 511.3
Sample C Male 372.0
Sample D Male 361.6
Periaqueductal gray
nTPM: 404.1
Samples: 3

Max nTPM: 422.0
Min nTPM: 378.0
Sample B Female 412.3
Sample C Male 422.0
Sample D Male 378.0
Superior colliculi
nTPM: 510.3
Samples: 4

Max nTPM: 601.0
Min nTPM: 408.4
Sample A Female 579.1
Sample B Female 601.0
Sample C Male 452.8
Sample D Male 408.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

785.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 785.1
Samples: 4

Max nTPM: 840.0
Min nTPM: 736.3
Sample A Male 840.0
Sample B Male 792.7
Sample C Female 736.3
Sample D Female 771.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

15.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.2
68191186 Antisense, RP_041122_02_H09, Mouse strain C57BL/6J (56 days, male) 15.2

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