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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:534.4 nTPM
HPA Brain:1180.6 nTPM
GTEx:534.4 nTPM
FANTOM5:681.7 Scaled Tags Per Million
Pig:845.7 nTPM
Mouse:1497.8 nTPM
Allen mouse:24.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1180.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 955.3
2586 Male, age 75, left hemisphere 1352.6
1827 Male, age 72, unknown 1158.5
2828 Female, age 72, unknown 1015.3
2411 Female, age 72, unknown 988.9
2019 Male, age 18, unknown 953.7
2666 Male, age 74, left hemisphere 927.1
1870 Female, age 42, unknown 834.0
2219 Male, age 76, both hemispheres 818.1
1833 Male, age 53, unknown 779.5
1830 Male, age 51, unknown 725.4
Dorsal raphe nucleus
nTPM: 1013.9
2298 Female, age 72, unknown 1289.0
2047 Male, age 72, unknown 1095.2
1828 Male, age 53, unknown 1031.4
2750 Male, age 76, both hemispheres 900.8
2016 Female, age 72, unknown 753.3
Inferior colliculus
nTPM: 870.3
2097 Female, age 72, unknown 1019.6
1848 Female, age 42, unknown 864.4
1890 Male, age 53, unknown 810.7
2849 Male, age 72, unknown 786.4
Median raphe nucleus
nTPM: 1019.6
2220 Male, age 76, midline 1019.6
Periaquaductal grey, anterior
nTPM: 1004.6
1947 Male, age 18, unknown 1091.7
1795 Male, age 51, unknown 1084.7
2502 Female, age 75, unknown 837.3
Periaquaductal grey, dorsal
nTPM: 764.7
1840 Male, age 53, unknown 860.0
1831 Male, age 72, unknown 803.1
2850 Male, age 76, both hemispheres 702.7
2464 Female, age 72, unknown 693.1
Periaquaductal grey, lateral
nTPM: 770.6
2272 Male, age 74, both hemispheres 886.2
2053 Male, age 18, unknown 773.9
2140 Male, age 76, both hemispheres 651.7
Pretectal area
nTPM: 1039.2
1816 Male, age 51, unknown 1392.6
2007 Male, age 72, unknown 1266.6
1944 Female, age 72, unknown 1264.5
1817 Female, age 42, unknown 1203.5
2667 Female, age 75, unknown 1175.5
1815 Male, age 53, unknown 1020.9
2224 Female, age 72, unknown 940.1
2273 Male, age 74, both hemispheres 930.9
2825 Male, age 18, unknown 824.6
2407 Male, age 75, both hemispheres 807.1
2316 Male, age 76, right hemisphere 605.3
Red nucleus
nTPM: 841.9
1821 Female, age 72, unknown 1018.2
2584 Male, age 75, left hemisphere 937.3
2785 Male, age 18, unknown 927.3
2725 Female, age 75, unknown 922.3
1954 Female, age 42, unknown 844.1
2503 Female, age 72, unknown 834.6
2769 Male, age 72, unknown 823.9
2227 Male, age 72, unknown 796.5
1865 Male, age 51, unknown 776.1
1904 Male, age 53, unknown 773.8
2588 Male, age 74, left hemisphere 760.1
2823 Male, age 76, right hemisphere 688.3
Substantia nigra
nTPM: 1180.6
1916 Female, age 42, unknown 1736.8
1941 Male, age 53, unknown 1414.7
1851 Male, age 51, unknown 1348.7
1889 Female, age 72, unknown 1251.7
2665 Male, age 74, both hemispheres 1101.5
2241 Male, age 72, unknown 1058.5
2583 Male, age 75, right hemisphere 1056.6
2409 Female, age 72, unknown 1017.5
2699 Male, age 18, unknown 976.7
2590 Female, age 75, unknown 843.0
Superior colliculus
nTPM: 920.6
2087 Female, age 72, unknown 1152.5
2668 Female, age 75, unknown 1150.2
1796 Male, age 53, unknown 1110.9
2261 Male, age 18, unknown 1051.0
2664 Male, age 75, both hemispheres 1029.1
2587 Male, age 74, left hemisphere 820.5
1839 Male, age 51, unknown 789.6
1895 Male, age 76, right hemisphere 754.8
1913 Female, age 42, unknown 700.0
1995 Male, age 72, unknown 647.9
Ventral tegmental area
nTPM: 1073.4
1915 Female, age 42, unknown 1291.7
2410 Female, age 72, unknown 1254.3
2218 Male, age 76, both hemispheres 1152.0
1942 Male, age 51, unknown 967.7
2223 Female, age 72, unknown 943.9
2021 Male, age 53, unknown 830.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

534.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 534.4
Samples: 139

Max nTPM: 1481.0
Min nTPM: 230.4
Std nTPM: 177.7
Median nTPM: 493.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1481.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1092.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 1011.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 868.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 837.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 823.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 819.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 803.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 803.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 797.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 796.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 796.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 786.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 785.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 783.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 776.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 764.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 760.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 756.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 734.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 732.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 719.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 710.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 703.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 700.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 699.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 696.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 692.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 688.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 687.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 662.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 659.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 638.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 637.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 630.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 622.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 613.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 607.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 607.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 605.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 604.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 589.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 586.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 565.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 565.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 564.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 557.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 554.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 553.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 550.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 549.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 536.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 534.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 534.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 534.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 532.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 527.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 527.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 527.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 525.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 522.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 518.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 515.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 512.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 507.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 505.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 502.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 500.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 496.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 493.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 492.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 478.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 475.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 470.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 468.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 464.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 464.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 461.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 458.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 454.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 450.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 449.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 449.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 449.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 448.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 447.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 446.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 442.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 442.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 440.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 437.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 437.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 435.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 432.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 431.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 431.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 430.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 430.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 429.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 428.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 428.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 423.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 423.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 417.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 415.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 415.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 408.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 407.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 402.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 401.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 400.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 392.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 391.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 391.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 384.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 381.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 381.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 379.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 378.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 369.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 369.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 366.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 365.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 365.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 365.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 358.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 356.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 351.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 351.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 345.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 341.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 332.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 329.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 328.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 316.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 296.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 290.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 261.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 230.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

681.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 681.7
FF:10158-103A5 76 years, female 681.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

845.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 712.5
Samples: 4

Max nTPM: 903.2
Min nTPM: 561.3
Sample A Female 903.2
Sample B Female 577.8
Sample C Male 807.5
Sample D Male 561.3
Midbrain
nTPM: 764.7
Samples: 4

Max nTPM: 910.9
Min nTPM: 647.9
Sample A Female 776.8
Sample B Female 647.9
Sample C Male 910.9
Sample D Male 723.3
Periaqueductal gray
nTPM: 613.1
Samples: 3

Max nTPM: 719.3
Min nTPM: 532.7
Sample B Female 587.4
Sample C Male 719.3
Sample D Male 532.7
Superior colliculi
nTPM: 845.7
Samples: 4

Max nTPM: 1009.3
Min nTPM: 689.4
Sample A Female 915.5
Sample B Female 689.4
Sample C Male 1009.3
Sample D Male 768.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1497.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 1497.8
Samples: 4

Max nTPM: 1632.2
Min nTPM: 1412.7
Sample A Male 1632.2
Sample B Male 1438.4
Sample C Female 1412.7
Sample D Female 1507.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

24.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 24.6
77620804 Antisense, RP_070129_03_H04, Mouse strain C57BL/6J (56 days, male) 24.6

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