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TMEM219
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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:212.3 nTPM
HPA Brain:109.3 nTPM
GTEx:212.3 nTPM
FANTOM5:43.3 Scaled Tags Per Million
Pig:34.7 nTPM
Mouse:22.2 nTPM
Allen mouse:0.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

109.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 105.7
2586 Male, age 75, left hemisphere 154.6
2828 Female, age 72, unknown 125.1
2666 Male, age 74, left hemisphere 107.3
2411 Female, age 72, unknown 107.0
1870 Female, age 42, unknown 105.8
1833 Male, age 53, unknown 96.2
2019 Male, age 18, unknown 96.0
1827 Male, age 72, unknown 94.9
1830 Male, age 51, unknown 93.6
2219 Male, age 76, both hemispheres 76.3
Dorsal raphe nucleus
nTPM: 104.0
2750 Male, age 76, both hemispheres 108.5
2016 Female, age 72, unknown 107.2
1828 Male, age 53, unknown 105.1
2298 Female, age 72, unknown 99.9
2047 Male, age 72, unknown 99.6
Inferior colliculus
nTPM: 86.9
2097 Female, age 72, unknown 89.3
1890 Male, age 53, unknown 87.8
2849 Male, age 72, unknown 86.3
1848 Female, age 42, unknown 84.3
Median raphe nucleus
nTPM: 95.8
2220 Male, age 76, midline 95.8
Periaquaductal grey, anterior
nTPM: 102.4
2502 Female, age 75, unknown 113.5
1795 Male, age 51, unknown 100.6
1947 Male, age 18, unknown 93.0
Periaquaductal grey, dorsal
nTPM: 91.8
1840 Male, age 53, unknown 98.9
2464 Female, age 72, unknown 93.2
1831 Male, age 72, unknown 90.3
2850 Male, age 76, both hemispheres 84.7
Periaquaductal grey, lateral
nTPM: 89.0
2053 Male, age 18, unknown 98.9
2140 Male, age 76, both hemispheres 92.5
2272 Male, age 74, both hemispheres 75.6
Pretectal area
nTPM: 87.2
2825 Male, age 18, unknown 102.3
1817 Female, age 42, unknown 95.2
2007 Male, age 72, unknown 92.8
1815 Male, age 53, unknown 91.3
2407 Male, age 75, both hemispheres 90.1
2667 Female, age 75, unknown 86.5
2316 Male, age 76, right hemisphere 86.1
1816 Male, age 51, unknown 84.5
2224 Female, age 72, unknown 80.4
1944 Female, age 72, unknown 75.2
2273 Male, age 74, both hemispheres 74.7
Red nucleus
nTPM: 109.3
2769 Male, age 72, unknown 120.3
1904 Male, age 53, unknown 116.0
2503 Female, age 72, unknown 115.3
1865 Male, age 51, unknown 113.9
2588 Male, age 74, left hemisphere 113.9
1954 Female, age 42, unknown 112.6
2227 Male, age 72, unknown 112.3
2584 Male, age 75, left hemisphere 111.9
1821 Female, age 72, unknown 109.5
2823 Male, age 76, right hemisphere 98.8
2785 Male, age 18, unknown 96.9
2725 Female, age 75, unknown 90.7
Substantia nigra
nTPM: 107.5
1851 Male, age 51, unknown 128.7
2665 Male, age 74, both hemispheres 127.3
2583 Male, age 75, right hemisphere 120.1
2699 Male, age 18, unknown 112.8
2590 Female, age 75, unknown 109.9
1916 Female, age 42, unknown 108.4
1941 Male, age 53, unknown 96.9
2241 Male, age 72, unknown 95.7
1889 Female, age 72, unknown 88.0
2409 Female, age 72, unknown 87.1
Superior colliculus
nTPM: 99.4
2664 Male, age 75, both hemispheres 135.8
1995 Male, age 72, unknown 105.3
1913 Female, age 42, unknown 104.3
2668 Female, age 75, unknown 103.5
1796 Male, age 53, unknown 96.1
2587 Male, age 74, left hemisphere 94.9
2261 Male, age 18, unknown 94.3
1839 Male, age 51, unknown 93.1
2087 Female, age 72, unknown 84.7
1895 Male, age 76, right hemisphere 81.9
Ventral tegmental area
nTPM: 107.8
1915 Female, age 42, unknown 120.7
2410 Female, age 72, unknown 113.9
2223 Female, age 72, unknown 111.6
2021 Male, age 53, unknown 105.9
1942 Male, age 51, unknown 104.1
2218 Male, age 76, both hemispheres 90.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

212.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 212.3
Samples: 139

Max nTPM: 593.6
Min nTPM: 94.0
Std nTPM: 75.0
Median nTPM: 193.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 593.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 485.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 424.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 382.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 381.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 371.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 349.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 338.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 334.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 331.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 323.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 312.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 307.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 306.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 304.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 304.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 301.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 293.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 291.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 288.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 281.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 279.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 277.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 275.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 268.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 260.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 258.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 252.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 252.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 251.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 250.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 250.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 249.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 248.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 247.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 246.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 245.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 245.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 242.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 241.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 238.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 238.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 236.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 236.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 234.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 231.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 227.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 222.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 220.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 219.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 217.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 217.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 216.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 214.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 214.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 213.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 213.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 212.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 212.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 206.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 205.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 202.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 201.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 201.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 200.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 200.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 199.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 194.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 194.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 193.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 193.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 192.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 192.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 190.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 187.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 185.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 185.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 185.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 184.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 183.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 181.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 181.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 180.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 179.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 179.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 178.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 176.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 176.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 176.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 175.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 175.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 174.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 174.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 173.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 172.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 172.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 171.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 171.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 169.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 169.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 166.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 165.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 163.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 162.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 162.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 162.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 161.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 159.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 157.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 156.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 156.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 156.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 152.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 151.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 147.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 146.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 146.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 146.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 145.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 144.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 143.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 141.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 141.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 140.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 140.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 138.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 135.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 132.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 130.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 128.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 125.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 123.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 123.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 123.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 121.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 120.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 119.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 96.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 94.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

43.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 43.3
FF:10158-103A5 76 years, female 43.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

34.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 32.4
Samples: 4

Max nTPM: 39.6
Min nTPM: 26.8
Sample A Female 39.6
Sample B Female 30.1
Sample C Male 33.2
Sample D Male 26.8
Midbrain
nTPM: 32.1
Samples: 4

Max nTPM: 43.6
Min nTPM: 27.1
Sample A Female 43.6
Sample B Female 28.2
Sample C Male 29.4
Sample D Male 27.1
Periaqueductal gray
nTPM: 28.6
Samples: 3

Max nTPM: 31.4
Min nTPM: 26.1
Sample B Female 28.4
Sample C Male 31.4
Sample D Male 26.1
Superior colliculi
nTPM: 34.7
Samples: 4

Max nTPM: 42.3
Min nTPM: 30.5
Sample A Female 42.3
Sample B Female 34.5
Sample C Male 30.5
Sample D Male 31.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

22.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 22.2
Samples: 4

Max nTPM: 25.4
Min nTPM: 20.0
Sample A Male 25.4
Sample B Male 21.0
Sample C Female 22.2
Sample D Female 20.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.0
68080705 Antisense, RP_040929_01_G04, Mouse strain C57BL/6J (56 days, male) 0.0

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