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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:172.6 nTPM
HPA Brain:510.3 nTPM
GTEx:172.6 nTPM
FANTOM5:625.8 Scaled Tags Per Million
Pig:130.1 nTPM
Mouse:91.2 nTPM
Allen mouse:4.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

510.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 344.9
1830 Male, age 51, unknown 470.4
2019 Male, age 18, unknown 455.1
1833 Male, age 53, unknown 435.0
2411 Female, age 72, unknown 409.1
1870 Female, age 42, unknown 399.3
2666 Male, age 74, left hemisphere 309.5
2828 Female, age 72, unknown 284.2
1827 Male, age 72, unknown 237.2
2219 Male, age 76, both hemispheres 224.6
2586 Male, age 75, left hemisphere 224.2
Dorsal raphe nucleus
nTPM: 246.8
2750 Male, age 76, both hemispheres 456.3
2016 Female, age 72, unknown 256.2
1828 Male, age 53, unknown 234.7
2047 Male, age 72, unknown 151.5
2298 Female, age 72, unknown 135.1
Inferior colliculus
nTPM: 231.1
1890 Male, age 53, unknown 247.5
1848 Female, age 42, unknown 239.4
2849 Male, age 72, unknown 238.6
2097 Female, age 72, unknown 199.0
Median raphe nucleus
nTPM: 211.8
2220 Male, age 76, midline 211.8
Periaquaductal grey, anterior
nTPM: 200.7
2502 Female, age 75, unknown 243.7
1947 Male, age 18, unknown 212.9
1795 Male, age 51, unknown 145.4
Periaquaductal grey, dorsal
nTPM: 162.2
2464 Female, age 72, unknown 264.8
1831 Male, age 72, unknown 172.4
2850 Male, age 76, both hemispheres 111.8
1840 Male, age 53, unknown 99.8
Periaquaductal grey, lateral
nTPM: 176.2
2272 Male, age 74, both hemispheres 220.3
2053 Male, age 18, unknown 197.0
2140 Male, age 76, both hemispheres 111.2
Pretectal area
nTPM: 232.2
2316 Male, age 76, right hemisphere 368.0
1815 Male, age 53, unknown 341.3
1817 Female, age 42, unknown 299.6
2007 Male, age 72, unknown 277.7
2407 Male, age 75, both hemispheres 218.1
2825 Male, age 18, unknown 217.9
2273 Male, age 74, both hemispheres 182.2
2224 Female, age 72, unknown 170.2
1944 Female, age 72, unknown 167.4
2667 Female, age 75, unknown 156.3
1816 Male, age 51, unknown 155.5
Red nucleus
nTPM: 510.3
1821 Female, age 72, unknown 681.1
1865 Male, age 51, unknown 672.4
2823 Male, age 76, right hemisphere 602.9
1904 Male, age 53, unknown 592.6
2503 Female, age 72, unknown 521.6
1954 Female, age 42, unknown 500.2
2785 Male, age 18, unknown 471.7
2227 Male, age 72, unknown 465.6
2769 Male, age 72, unknown 457.3
2588 Male, age 74, left hemisphere 434.7
2725 Female, age 75, unknown 430.2
2584 Male, age 75, left hemisphere 293.6
Substantia nigra
nTPM: 287.5
2409 Female, age 72, unknown 425.8
1889 Female, age 72, unknown 325.9
1851 Male, age 51, unknown 321.2
2590 Female, age 75, unknown 310.3
2241 Male, age 72, unknown 308.5
2699 Male, age 18, unknown 282.8
2583 Male, age 75, right hemisphere 257.5
1941 Male, age 53, unknown 236.9
2665 Male, age 74, both hemispheres 207.1
1916 Female, age 42, unknown 198.4
Superior colliculus
nTPM: 304.2
1895 Male, age 76, right hemisphere 500.5
1995 Male, age 72, unknown 415.9
1913 Female, age 42, unknown 412.5
2668 Female, age 75, unknown 337.8
2587 Male, age 74, left hemisphere 324.7
1839 Male, age 51, unknown 323.1
1796 Male, age 53, unknown 214.4
2087 Female, age 72, unknown 177.7
2261 Male, age 18, unknown 173.5
2664 Male, age 75, both hemispheres 161.9
Ventral tegmental area
nTPM: 293.1
2223 Female, age 72, unknown 407.0
2410 Female, age 72, unknown 388.0
2218 Male, age 76, both hemispheres 250.4
1915 Female, age 42, unknown 249.0
2021 Male, age 53, unknown 246.3
1942 Male, age 51, unknown 217.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

172.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 172.6
Samples: 139

Max nTPM: 450.7
Min nTPM: 64.6
Std nTPM: 80.7
Median nTPM: 148.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 450.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 418.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 412.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 373.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 373.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 369.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 368.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 342.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 332.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 331.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 317.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 312.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 309.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 287.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 280.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 278.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 277.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 276.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 271.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 266.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 266.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 257.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 251.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 240.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 237.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 232.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 232.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 228.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 225.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 223.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 219.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 215.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 209.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 205.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 205.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 204.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 201.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 198.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 198.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 197.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 191.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 191.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 188.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 187.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 186.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 185.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 185.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 180.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 180.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 177.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 176.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 175.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 164.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 163.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 161.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 161.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 160.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 160.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 160.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 159.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 159.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 158.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 156.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 155.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 153.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 153.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 152.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 150.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 148.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 148.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 147.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 146.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 142.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 142.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 141.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 140.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 139.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 138.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 137.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 137.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 136.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 135.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 135.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 135.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 134.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 134.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 134.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 134.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 132.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 131.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 131.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 131.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 130.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 130.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 130.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 129.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 128.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 126.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 126.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 124.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 123.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 123.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 122.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 121.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 121.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 120.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 119.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 117.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 116.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 114.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 113.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 113.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 110.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 110.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 105.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 105.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 104.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 103.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 98.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 97.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 96.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 94.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 94.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 93.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 93.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 92.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 88.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 84.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 83.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 83.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 82.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 80.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 74.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 71.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 70.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 69.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 68.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 67.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 64.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

625.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 625.8
FF:10158-103A5 76 years, female 625.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

130.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 103.7
Samples: 4

Max nTPM: 164.7
Min nTPM: 64.0
Sample A Female 106.1
Sample B Female 64.0
Sample C Male 80.1
Sample D Male 164.7
Midbrain
nTPM: 130.1
Samples: 4

Max nTPM: 271.9
Min nTPM: 68.3
Sample A Female 271.9
Sample B Female 109.4
Sample C Male 70.7
Sample D Male 68.3
Periaqueductal gray
nTPM: 73.5
Samples: 3

Max nTPM: 89.9
Min nTPM: 56.4
Sample B Female 89.9
Sample C Male 56.4
Sample D Male 74.2
Superior colliculi
nTPM: 90.9
Samples: 4

Max nTPM: 114.5
Min nTPM: 47.6
Sample A Female 100.2
Sample B Female 47.6
Sample C Male 101.1
Sample D Male 114.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

91.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 91.3
Samples: 4

Max nTPM: 94.1
Min nTPM: 87.3
Sample A Male 87.3
Sample B Male 90.7
Sample C Female 92.9
Sample D Female 94.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.6
75146004 Antisense, RP_060220_02_B10, Mouse strain C57BL/6J (56 days, male) 6.4
564654 Antisense, RP_040826_01_B12, Mouse strain C57BL/6J (56 days, male) 2.7

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