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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:605.4 nTPM
HPA Brain:761.5 nTPM
GTEx:605.4 nTPM
FANTOM5:1018.7 Scaled Tags Per Million
Pig:1247.3 nTPM
Mouse:2601.7 nTPM
Allen mouse:21.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

761.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 334.7
1830 Male, age 51, unknown 483.3
2586 Male, age 75, left hemisphere 479.2
1833 Male, age 53, unknown 391.8
2411 Female, age 72, unknown 384.2
2019 Male, age 18, unknown 331.4
2219 Male, age 76, both hemispheres 320.8
2828 Female, age 72, unknown 265.9
2666 Male, age 74, left hemisphere 253.9
1870 Female, age 42, unknown 235.2
1827 Male, age 72, unknown 201.7
Dorsal raphe nucleus
nTPM: 761.5
2047 Male, age 72, unknown 1130.3
2016 Female, age 72, unknown 787.4
1828 Male, age 53, unknown 765.4
2298 Female, age 72, unknown 660.6
2750 Male, age 76, both hemispheres 464.1
Inferior colliculus
nTPM: 508.6
1890 Male, age 53, unknown 696.8
2097 Female, age 72, unknown 666.9
2849 Male, age 72, unknown 387.1
1848 Female, age 42, unknown 283.5
Median raphe nucleus
nTPM: 683.5
2220 Male, age 76, midline 683.5
Periaquaductal grey, anterior
nTPM: 361.9
1947 Male, age 18, unknown 585.8
2502 Female, age 75, unknown 320.3
1795 Male, age 51, unknown 179.6
Periaquaductal grey, dorsal
nTPM: 448.0
2850 Male, age 76, both hemispheres 644.6
1840 Male, age 53, unknown 472.6
2464 Female, age 72, unknown 428.8
1831 Male, age 72, unknown 245.8
Periaquaductal grey, lateral
nTPM: 315.7
2140 Male, age 76, both hemispheres 460.2
2272 Male, age 74, both hemispheres 280.5
2053 Male, age 18, unknown 206.3
Pretectal area
nTPM: 220.4
2273 Male, age 74, both hemispheres 438.0
2407 Male, age 75, both hemispheres 351.2
2825 Male, age 18, unknown 311.5
2224 Female, age 72, unknown 311.2
2316 Male, age 76, right hemisphere 219.1
2667 Female, age 75, unknown 181.8
1817 Female, age 42, unknown 146.9
1944 Female, age 72, unknown 139.6
2007 Male, age 72, unknown 121.5
1816 Male, age 51, unknown 113.8
1815 Male, age 53, unknown 89.8
Red nucleus
nTPM: 502.2
1821 Female, age 72, unknown 749.7
1865 Male, age 51, unknown 685.7
1954 Female, age 42, unknown 667.1
2725 Female, age 75, unknown 587.7
2769 Male, age 72, unknown 569.3
2227 Male, age 72, unknown 565.1
2503 Female, age 72, unknown 465.3
1904 Male, age 53, unknown 426.7
2823 Male, age 76, right hemisphere 412.9
2588 Male, age 74, left hemisphere 352.5
2584 Male, age 75, left hemisphere 338.7
2785 Male, age 18, unknown 205.5
Substantia nigra
nTPM: 692.0
2699 Male, age 18, unknown 1241.7
1916 Female, age 42, unknown 900.7
2241 Male, age 72, unknown 792.4
1851 Male, age 51, unknown 737.8
1941 Male, age 53, unknown 688.8
2590 Female, age 75, unknown 667.7
2665 Male, age 74, both hemispheres 588.1
2409 Female, age 72, unknown 508.2
2583 Male, age 75, right hemisphere 455.7
1889 Female, age 72, unknown 339.4
Superior colliculus
nTPM: 257.0
1995 Male, age 72, unknown 480.3
1913 Female, age 42, unknown 358.1
2587 Male, age 74, left hemisphere 314.5
1796 Male, age 53, unknown 274.3
2664 Male, age 75, both hemispheres 265.3
1839 Male, age 51, unknown 211.5
2668 Female, age 75, unknown 203.8
1895 Male, age 76, right hemisphere 169.8
2087 Female, age 72, unknown 151.8
2261 Male, age 18, unknown 140.2
Ventral tegmental area
nTPM: 655.1
1942 Male, age 51, unknown 896.5
2223 Female, age 72, unknown 800.8
1915 Female, age 42, unknown 684.5
2021 Male, age 53, unknown 603.6
2218 Male, age 76, both hemispheres 522.8
2410 Female, age 72, unknown 422.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

605.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 605.4
Samples: 139

Max nTPM: 2408.5
Min nTPM: 154.5
Std nTPM: 401.5
Median nTPM: 483.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 2408.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 2163.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 2119.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1733.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1718.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1508.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 1497.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1415.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1330.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1257.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1246.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1187.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1168.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1098.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1079.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1067.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 1021.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 986.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 969.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 956.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 938.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 872.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 864.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 864.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 846.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 829.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 829.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 828.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 813.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 813.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 776.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 775.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 741.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 721.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 718.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 716.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 711.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 696.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 688.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 683.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 664.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 653.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 653.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 652.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 638.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 638.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 632.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 629.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 628.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 619.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 603.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 597.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 589.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 573.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 573.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 570.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 555.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 544.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 526.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 523.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 522.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 521.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 516.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 508.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 507.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 502.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 502.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 500.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 487.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 483.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 482.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 480.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 475.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 463.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 463.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 460.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 451.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 451.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 448.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 442.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 436.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 428.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 424.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 423.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 422.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 421.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 417.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 413.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 408.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 407.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 407.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 403.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 397.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 393.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 391.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 387.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 384.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 383.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 380.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 380.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 377.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 371.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 367.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 360.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 356.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 353.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 344.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 344.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 337.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 336.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 331.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 317.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 311.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 308.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 300.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 296.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 292.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 278.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 276.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 276.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 269.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 264.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 262.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 260.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 260.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 255.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 238.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 231.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 212.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 212.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 204.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 201.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 199.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 185.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 179.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 179.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 162.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 159.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 154.5
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1018.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1018.7
FF:10158-103A5 76 years, female 1018.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1247.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 1122.4
Samples: 4

Max nTPM: 1199.0
Min nTPM: 1063.5
Sample A Female 1163.2
Sample B Female 1199.0
Sample C Male 1063.5
Sample D Male 1064.0
Midbrain
nTPM: 1124.6
Samples: 4

Max nTPM: 1324.8
Min nTPM: 1035.5
Sample A Female 1073.2
Sample B Female 1324.8
Sample C Male 1065.0
Sample D Male 1035.5
Periaqueductal gray
nTPM: 1247.3
Samples: 3

Max nTPM: 1484.0
Min nTPM: 1034.9
Sample B Female 1484.0
Sample C Male 1223.0
Sample D Male 1034.9
Superior colliculi
nTPM: 984.8
Samples: 4

Max nTPM: 1136.0
Min nTPM: 558.3
Sample A Female 1135.1
Sample B Female 558.3
Sample C Male 1109.8
Sample D Male 1136.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

2601.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 2601.8
Samples: 4

Max nTPM: 2678.0
Min nTPM: 2560.3
Sample A Male 2560.3
Sample B Male 2572.5
Sample C Female 2678.0
Sample D Female 2596.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

21.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 21.6
70429447 Antisense, RP_050614_01_F10, Mouse strain C57BL/6J (56 days, male) 21.6
74750016 Antisense, RP_060220_05_E06, Mouse strain C57BL/6J (56 days, male) 21.5

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