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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:1604.1 nTPM
HPA Brain:441.0 nTPM
GTEx:1604.1 nTPM
FANTOM5:532.1 Scaled Tags Per Million
Pig:126.5 nTPM
Mouse:391.5 nTPM
Allen mouse:4.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

441.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 380.1
2666 Male, age 74, left hemisphere 448.7
1870 Female, age 42, unknown 430.1
1830 Male, age 51, unknown 411.1
2411 Female, age 72, unknown 396.5
1833 Male, age 53, unknown 394.3
2828 Female, age 72, unknown 391.8
2019 Male, age 18, unknown 340.3
2219 Male, age 76, both hemispheres 340.0
2586 Male, age 75, left hemisphere 331.0
1827 Male, age 72, unknown 317.4
Dorsal raphe nucleus
nTPM: 393.1
2016 Female, age 72, unknown 444.6
2750 Male, age 76, both hemispheres 408.8
2298 Female, age 72, unknown 401.3
1828 Male, age 53, unknown 366.6
2047 Male, age 72, unknown 344.3
Inferior colliculus
nTPM: 354.3
2849 Male, age 72, unknown 369.7
1890 Male, age 53, unknown 368.0
1848 Female, age 42, unknown 341.3
2097 Female, age 72, unknown 338.1
Median raphe nucleus
nTPM: 361.9
2220 Male, age 76, midline 361.9
Periaquaductal grey, anterior
nTPM: 357.1
2502 Female, age 75, unknown 431.9
1947 Male, age 18, unknown 320.8
1795 Male, age 51, unknown 318.6
Periaquaductal grey, dorsal
nTPM: 373.2
2850 Male, age 76, both hemispheres 429.5
1840 Male, age 53, unknown 369.3
1831 Male, age 72, unknown 367.5
2464 Female, age 72, unknown 326.4
Periaquaductal grey, lateral
nTPM: 368.0
2053 Male, age 18, unknown 410.8
2140 Male, age 76, both hemispheres 393.4
2272 Male, age 74, both hemispheres 299.9
Pretectal area
nTPM: 345.1
1815 Male, age 53, unknown 406.3
2224 Female, age 72, unknown 380.1
2316 Male, age 76, right hemisphere 374.2
2825 Male, age 18, unknown 360.6
1817 Female, age 42, unknown 358.7
2407 Male, age 75, both hemispheres 349.9
2007 Male, age 72, unknown 348.5
1944 Female, age 72, unknown 314.5
2667 Female, age 75, unknown 309.3
2273 Male, age 74, both hemispheres 308.3
1816 Male, age 51, unknown 286.2
Red nucleus
nTPM: 441.0
1865 Male, age 51, unknown 524.0
2503 Female, age 72, unknown 519.4
1821 Female, age 72, unknown 489.2
1904 Male, age 53, unknown 468.7
2725 Female, age 75, unknown 450.9
2227 Male, age 72, unknown 437.5
2769 Male, age 72, unknown 429.2
2584 Male, age 75, left hemisphere 411.9
1954 Female, age 42, unknown 401.7
2823 Male, age 76, right hemisphere 395.5
2785 Male, age 18, unknown 395.0
2588 Male, age 74, left hemisphere 369.3
Substantia nigra
nTPM: 431.2
2699 Male, age 18, unknown 620.2
1851 Male, age 51, unknown 513.8
2665 Male, age 74, both hemispheres 488.9
2409 Female, age 72, unknown 448.4
1916 Female, age 42, unknown 428.1
1889 Female, age 72, unknown 414.8
2241 Male, age 72, unknown 397.2
2590 Female, age 75, unknown 372.5
1941 Male, age 53, unknown 348.8
2583 Male, age 75, right hemisphere 279.4
Superior colliculus
nTPM: 395.4
1995 Male, age 72, unknown 543.2
1913 Female, age 42, unknown 501.0
2587 Male, age 74, left hemisphere 499.7
2668 Female, age 75, unknown 387.4
1839 Male, age 51, unknown 376.9
1796 Male, age 53, unknown 360.3
2664 Male, age 75, both hemispheres 345.2
1895 Male, age 76, right hemisphere 342.2
2261 Male, age 18, unknown 302.0
2087 Female, age 72, unknown 296.5
Ventral tegmental area
nTPM: 426.6
1915 Female, age 42, unknown 468.9
2410 Female, age 72, unknown 455.8
2223 Female, age 72, unknown 448.4
2021 Male, age 53, unknown 432.2
2218 Male, age 76, both hemispheres 387.6
1942 Male, age 51, unknown 366.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1604.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1604.1
Samples: 139

Max nTPM: 4794.8
Min nTPM: 474.1
Std nTPM: 665.7
Median nTPM: 1509.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 4794.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 4098.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 3856.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 3502.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 2867.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 2850.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 2827.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 2800.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 2670.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 2631.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 2626.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 2556.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 2458.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 2307.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2307.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 2288.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 2264.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2212.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 2207.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 2206.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 2197.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 2180.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 2157.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 2131.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 2087.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 2084.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 2041.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 2012.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1978.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1961.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1957.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1948.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1943.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1937.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1937.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1862.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1856.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1831.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1824.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1819.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1809.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1804.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1790.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1789.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1788.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1778.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1760.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1749.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1746.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1708.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1695.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1672.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1668.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1654.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1653.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1638.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1637.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1630.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1618.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1609.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1593.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1561.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1560.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1556.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1554.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1542.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1530.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1522.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1514.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1509.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1500.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1488.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1419.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1403.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1399.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1391.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1373.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1359.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1353.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1336.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1322.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1319.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1307.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1290.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1289.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1284.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1280.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1272.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 1269.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 1269.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1256.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1239.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1238.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1232.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1221.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1220.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1201.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1201.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 1191.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1167.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1159.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1158.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 1156.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1139.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1118.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1102.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 1099.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 1093.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1086.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 1084.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1073.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1062.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1057.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1043.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1043.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1041.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1033.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1018.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 1017.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 993.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 990.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 989.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 974.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 974.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 953.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 953.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 948.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 944.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 941.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 932.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 913.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 899.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 877.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 867.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 820.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 726.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 711.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 665.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 474.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

532.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 532.1
FF:10158-103A5 76 years, female 532.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

126.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 118.6
Samples: 4

Max nTPM: 180.8
Min nTPM: 82.8
Sample A Female 180.8
Sample B Female 124.7
Sample C Male 82.8
Sample D Male 86.0
Midbrain
nTPM: 113.6
Samples: 4

Max nTPM: 173.5
Min nTPM: 75.3
Sample A Female 173.5
Sample B Female 117.7
Sample C Male 88.0
Sample D Male 75.3
Periaqueductal gray
nTPM: 82.9
Samples: 3

Max nTPM: 92.8
Min nTPM: 72.3
Sample B Female 92.8
Sample C Male 83.7
Sample D Male 72.3
Superior colliculi
nTPM: 126.5
Samples: 4

Max nTPM: 164.6
Min nTPM: 94.8
Sample A Female 164.6
Sample B Female 144.6
Sample C Male 102.1
Sample D Male 94.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

391.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 391.4
Samples: 4

Max nTPM: 435.8
Min nTPM: 351.7
Sample A Male 435.8
Sample B Male 398.8
Sample C Female 351.7
Sample D Female 379.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.8
100143515 Antisense, RP_110407_01_E05, Mouse strain C57BL/6J (56 days, male) 4.8

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