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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:563.4 nTPM
HPA Brain:235.2 nTPM
GTEx:563.4 nTPM
FANTOM5:176.7 Scaled Tags Per Million
Pig:0.0 nTPM
Mouse:473.1 nTPM
Allen mouse:12.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

235.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 189.5
2586 Male, age 75, left hemisphere 224.3
1870 Female, age 42, unknown 200.7
2828 Female, age 72, unknown 199.3
2019 Male, age 18, unknown 197.0
2666 Male, age 74, left hemisphere 192.9
1827 Male, age 72, unknown 189.4
2411 Female, age 72, unknown 184.7
2219 Male, age 76, both hemispheres 174.0
1830 Male, age 51, unknown 166.7
1833 Male, age 53, unknown 166.0
Dorsal raphe nucleus
nTPM: 203.7
2298 Female, age 72, unknown 242.1
2750 Male, age 76, both hemispheres 206.1
1828 Male, age 53, unknown 202.1
2016 Female, age 72, unknown 193.9
2047 Male, age 72, unknown 174.3
Inferior colliculus
nTPM: 188.3
2097 Female, age 72, unknown 209.1
1890 Male, age 53, unknown 205.1
1848 Female, age 42, unknown 178.0
2849 Male, age 72, unknown 160.9
Median raphe nucleus
nTPM: 201.1
2220 Male, age 76, midline 201.1
Periaquaductal grey, anterior
nTPM: 235.2
2502 Female, age 75, unknown 277.8
1795 Male, age 51, unknown 221.6
1947 Male, age 18, unknown 206.3
Periaquaductal grey, dorsal
nTPM: 181.0
1831 Male, age 72, unknown 196.5
1840 Male, age 53, unknown 193.4
2850 Male, age 76, both hemispheres 167.5
2464 Female, age 72, unknown 166.7
Periaquaductal grey, lateral
nTPM: 182.2
2272 Male, age 74, both hemispheres 194.2
2140 Male, age 76, both hemispheres 177.6
2053 Male, age 18, unknown 174.8
Pretectal area
nTPM: 192.1
2007 Male, age 72, unknown 229.7
1817 Female, age 42, unknown 219.4
2224 Female, age 72, unknown 213.0
1816 Male, age 51, unknown 212.8
2316 Male, age 76, right hemisphere 195.6
1944 Female, age 72, unknown 187.8
2273 Male, age 74, both hemispheres 186.3
1815 Male, age 53, unknown 183.0
2825 Male, age 18, unknown 171.8
2667 Female, age 75, unknown 159.5
2407 Male, age 75, both hemispheres 153.8
Red nucleus
nTPM: 210.5
2503 Female, age 72, unknown 297.0
2769 Male, age 72, unknown 227.3
2227 Male, age 72, unknown 225.4
2785 Male, age 18, unknown 225.1
1904 Male, age 53, unknown 214.2
1865 Male, age 51, unknown 213.0
1821 Female, age 72, unknown 211.1
2725 Female, age 75, unknown 200.5
2584 Male, age 75, left hemisphere 195.5
2588 Male, age 74, left hemisphere 182.8
1954 Female, age 42, unknown 180.8
2823 Male, age 76, right hemisphere 153.0
Substantia nigra
nTPM: 207.7
1851 Male, age 51, unknown 264.4
1916 Female, age 42, unknown 257.3
2699 Male, age 18, unknown 220.1
2665 Male, age 74, both hemispheres 211.1
1889 Female, age 72, unknown 207.5
1941 Male, age 53, unknown 195.8
2590 Female, age 75, unknown 194.1
2409 Female, age 72, unknown 180.0
2241 Male, age 72, unknown 175.8
2583 Male, age 75, right hemisphere 171.2
Superior colliculus
nTPM: 200.2
1796 Male, age 53, unknown 224.0
2668 Female, age 75, unknown 219.3
2587 Male, age 74, left hemisphere 218.5
2261 Male, age 18, unknown 215.1
1913 Female, age 42, unknown 214.6
1995 Male, age 72, unknown 201.6
2087 Female, age 72, unknown 200.3
2664 Male, age 75, both hemispheres 178.2
1895 Male, age 76, right hemisphere 168.8
1839 Male, age 51, unknown 161.7
Ventral tegmental area
nTPM: 214.6
1915 Female, age 42, unknown 240.2
2223 Female, age 72, unknown 229.9
1942 Male, age 51, unknown 213.5
2410 Female, age 72, unknown 211.5
2218 Male, age 76, both hemispheres 196.6
2021 Male, age 53, unknown 196.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

563.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 563.4
Samples: 139

Max nTPM: 1290.3
Min nTPM: 214.1
Std nTPM: 171.6
Median nTPM: 539.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1290.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1268.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 979.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 970.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 922.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 913.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 890.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 889.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 825.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 822.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 790.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 781.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 777.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 774.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 754.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 742.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 731.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 723.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 722.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 721.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 721.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 714.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 709.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 707.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 682.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 681.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 680.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 677.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 672.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 659.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 653.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 652.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 647.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 645.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 640.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 638.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 636.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 636.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 632.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 632.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 626.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 625.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 624.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 624.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 624.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 624.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 621.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 616.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 613.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 606.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 605.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 599.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 597.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 596.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 595.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 591.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 588.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 586.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 585.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 583.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 582.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 566.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 565.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 564.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 555.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 552.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 546.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 546.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 540.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 539.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 538.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 538.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 534.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 523.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 523.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 519.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 518.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 517.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 512.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 508.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 504.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 502.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 501.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 500.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 495.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 494.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 491.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 488.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 485.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 484.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 483.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 479.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 478.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 477.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 475.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 474.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 468.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 464.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 462.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 459.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 456.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 452.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 452.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 449.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 447.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 445.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 443.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 439.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 436.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 436.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 434.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 432.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 426.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 419.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 418.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 418.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 414.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 411.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 404.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 403.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 401.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 400.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 389.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 386.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 386.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 378.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 377.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 371.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 354.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 345.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 344.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 331.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 323.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 317.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 316.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 294.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 269.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 255.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 214.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

176.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 176.7
FF:10158-103A5 76 years, female 176.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 0.0
Samples: 4

Max nTPM: 0.0
Min nTPM: 0.0
Sample A Female 0.0
Sample B Female 0.0
Sample C Male 0.0
Sample D Male 0.0
Midbrain
nTPM: 0.0
Samples: 4

Max nTPM: 0.0
Min nTPM: 0.0
Sample A Female 0.0
Sample B Female 0.0
Sample C Male 0.0
Sample D Male 0.0
Periaqueductal gray
nTPM: 0.0
Samples: 3

Max nTPM: 0.1
Min nTPM: 0.0
Sample B Female 0.0
Sample C Male 0.1
Sample D Male 0.0
Superior colliculi
nTPM: 0.0
Samples: 4

Max nTPM: 0.0
Min nTPM: 0.0
Sample A Female 0.0
Sample B Female 0.0
Sample C Male 0.0
Sample D Male 0.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

473.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 473.1
Samples: 4

Max nTPM: 532.3
Min nTPM: 422.1
Sample A Male 532.3
Sample B Male 459.7
Sample C Female 422.1
Sample D Female 478.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

12.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.7
69818338 Antisense, RP_050510_04_H06, Mouse strain C57BL/6J (56 days, male) 12.9
74749928 Antisense, RP_060220_04_F02, Mouse strain C57BL/6J (56 days, male) 12.6

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