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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:449.5 nTPM
HPA Brain:330.1 nTPM
GTEx:449.5 nTPM
FANTOM5:252.9 Scaled Tags Per Million
Pig:193.8 nTPM
Mouse:401.2 nTPM
Allen mouse:12.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

330.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 216.7
1827 Male, age 72, unknown 266.9
1870 Female, age 42, unknown 248.3
2219 Male, age 76, both hemispheres 246.8
2411 Female, age 72, unknown 244.3
1833 Male, age 53, unknown 237.4
2666 Male, age 74, left hemisphere 207.1
2586 Male, age 75, left hemisphere 200.3
1830 Male, age 51, unknown 197.2
2828 Female, age 72, unknown 183.6
2019 Male, age 18, unknown 135.4
Dorsal raphe nucleus
nTPM: 259.9
2047 Male, age 72, unknown 304.4
2298 Female, age 72, unknown 287.6
1828 Male, age 53, unknown 260.1
2750 Male, age 76, both hemispheres 245.2
2016 Female, age 72, unknown 202.2
Inferior colliculus
nTPM: 245.4
2849 Male, age 72, unknown 282.0
1848 Female, age 42, unknown 242.6
2097 Female, age 72, unknown 240.0
1890 Male, age 53, unknown 217.1
Median raphe nucleus
nTPM: 330.1
2220 Male, age 76, midline 330.1
Periaquaductal grey, anterior
nTPM: 249.6
1947 Male, age 18, unknown 322.8
1795 Male, age 51, unknown 229.0
2502 Female, age 75, unknown 197.0
Periaquaductal grey, dorsal
nTPM: 247.8
1840 Male, age 53, unknown 286.8
2850 Male, age 76, both hemispheres 265.1
2464 Female, age 72, unknown 224.2
1831 Male, age 72, unknown 215.0
Periaquaductal grey, lateral
nTPM: 216.7
2140 Male, age 76, both hemispheres 235.5
2053 Male, age 18, unknown 224.5
2272 Male, age 74, both hemispheres 190.0
Pretectal area
nTPM: 225.9
2224 Female, age 72, unknown 287.9
2825 Male, age 18, unknown 279.6
1816 Male, age 51, unknown 234.0
2667 Female, age 75, unknown 231.2
1944 Female, age 72, unknown 221.4
2007 Male, age 72, unknown 219.3
1817 Female, age 42, unknown 211.2
1815 Male, age 53, unknown 209.1
2273 Male, age 74, both hemispheres 199.7
2316 Male, age 76, right hemisphere 198.9
2407 Male, age 75, both hemispheres 192.0
Red nucleus
nTPM: 192.6
1821 Female, age 72, unknown 247.6
2725 Female, age 75, unknown 242.7
1954 Female, age 42, unknown 205.5
2503 Female, age 72, unknown 200.6
2588 Male, age 74, left hemisphere 196.4
2823 Male, age 76, right hemisphere 190.7
2227 Male, age 72, unknown 189.1
2769 Male, age 72, unknown 181.6
1865 Male, age 51, unknown 181.5
1904 Male, age 53, unknown 175.0
2584 Male, age 75, left hemisphere 167.5
2785 Male, age 18, unknown 132.4
Substantia nigra
nTPM: 249.0
1916 Female, age 42, unknown 351.4
2699 Male, age 18, unknown 288.1
1851 Male, age 51, unknown 272.5
1941 Male, age 53, unknown 251.3
1889 Female, age 72, unknown 251.1
2241 Male, age 72, unknown 246.5
2665 Male, age 74, both hemispheres 226.4
2590 Female, age 75, unknown 224.0
2409 Female, age 72, unknown 200.7
2583 Male, age 75, right hemisphere 177.8
Superior colliculus
nTPM: 207.4
1895 Male, age 76, right hemisphere 244.2
1839 Male, age 51, unknown 233.2
2261 Male, age 18, unknown 229.5
1796 Male, age 53, unknown 216.5
2587 Male, age 74, left hemisphere 216.5
2668 Female, age 75, unknown 211.4
2664 Male, age 75, both hemispheres 206.7
2087 Female, age 72, unknown 193.9
1913 Female, age 42, unknown 174.8
1995 Male, age 72, unknown 147.0
Ventral tegmental area
nTPM: 261.9
1915 Female, age 42, unknown 314.4
2218 Male, age 76, both hemispheres 292.1
2410 Female, age 72, unknown 246.9
2021 Male, age 53, unknown 240.2
2223 Female, age 72, unknown 239.7
1942 Male, age 51, unknown 238.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

449.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 449.5
Samples: 139

Max nTPM: 995.5
Min nTPM: 221.4
Std nTPM: 127.9
Median nTPM: 436.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 995.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 868.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 773.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 772.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 711.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 696.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 681.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 679.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 655.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 641.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 640.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 637.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 629.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 622.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 617.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 600.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 595.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 582.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 568.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 566.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 564.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 563.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 563.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 561.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 560.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 557.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 556.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 547.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 543.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 542.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 530.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 526.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 522.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 521.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 517.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 510.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 510.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 509.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 505.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 503.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 497.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 495.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 492.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 489.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 488.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 486.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 484.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 482.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 480.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 479.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 478.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 477.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 471.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 468.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 467.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 466.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 465.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 462.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 459.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 457.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 457.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 456.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 454.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 450.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 447.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 445.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 442.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 442.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 439.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 436.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 435.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 433.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 431.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 427.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 425.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 412.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 411.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 408.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 408.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 406.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 406.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 401.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 399.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 396.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 395.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 394.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 388.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 386.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 386.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 385.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 380.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 380.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 377.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 375.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 374.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 373.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 373.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 372.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 372.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 370.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 370.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 368.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 368.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 365.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 362.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 356.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 356.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 352.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 349.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 349.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 349.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 346.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 345.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 344.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 325.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 325.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 322.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 322.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 316.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 311.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 310.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 310.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 310.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 306.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 304.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 302.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 298.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 297.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 296.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 289.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 289.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 283.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 283.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 275.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 268.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 255.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 255.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 246.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 221.4
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

252.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 252.9
FF:10158-103A5 76 years, female 252.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

193.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 181.3
Samples: 4

Max nTPM: 277.4
Min nTPM: 81.1
Sample A Female 277.4
Sample B Female 139.9
Sample C Male 226.6
Sample D Male 81.1
Midbrain
nTPM: 193.8
Samples: 4

Max nTPM: 218.9
Min nTPM: 157.5
Sample A Female 157.5
Sample B Female 183.2
Sample C Male 218.9
Sample D Male 215.5
Periaqueductal gray
nTPM: 193.0
Samples: 3

Max nTPM: 240.0
Min nTPM: 163.1
Sample B Female 175.8
Sample C Male 240.0
Sample D Male 163.1
Superior colliculi
nTPM: 188.5
Samples: 4

Max nTPM: 237.9
Min nTPM: 128.2
Sample A Female 237.9
Sample B Female 128.2
Sample C Male 210.5
Sample D Male 177.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

401.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 401.2
Samples: 4

Max nTPM: 414.0
Min nTPM: 372.1
Sample A Male 414.0
Sample B Male 408.5
Sample C Female 372.1
Sample D Female 410.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

12.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.0
1786 Antisense, RP_040526_02_H04, Mouse strain C57BL/6J (56 days, male) 12.0
1787 Antisense, RP_040526_02_H04, Mouse strain C57BL/6J (56 days, male) 11.5

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