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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:707.2 nTPM
HPA Brain:728.9 nTPM
GTEx:707.2 nTPM
FANTOM5:754.1 Scaled Tags Per Million
Mouse:139.7 nTPM
Allen mouse:0.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

728.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 454.8
2828 Female, age 72, unknown 1120.4
1870 Female, age 42, unknown 588.6
2586 Male, age 75, left hemisphere 553.0
1827 Male, age 72, unknown 531.3
2666 Male, age 74, left hemisphere 451.0
1830 Male, age 51, unknown 327.6
1833 Male, age 53, unknown 282.6
2019 Male, age 18, unknown 263.6
2411 Female, age 72, unknown 240.6
2219 Male, age 76, both hemispheres 189.0
Dorsal raphe nucleus
nTPM: 418.6
2016 Female, age 72, unknown 747.5
1828 Male, age 53, unknown 471.9
2047 Male, age 72, unknown 323.1
2750 Male, age 76, both hemispheres 290.2
2298 Female, age 72, unknown 260.5
Inferior colliculus
nTPM: 339.8
1848 Female, age 42, unknown 488.9
2849 Male, age 72, unknown 424.4
1890 Male, age 53, unknown 229.9
2097 Female, age 72, unknown 215.7
Median raphe nucleus
nTPM: 366.3
2220 Male, age 76, midline 366.3
Periaquaductal grey, anterior
nTPM: 483.6
1795 Male, age 51, unknown 628.9
2502 Female, age 75, unknown 531.6
1947 Male, age 18, unknown 290.3
Periaquaductal grey, dorsal
nTPM: 549.3
1831 Male, age 72, unknown 847.2
2850 Male, age 76, both hemispheres 620.3
1840 Male, age 53, unknown 479.3
2464 Female, age 72, unknown 250.5
Periaquaductal grey, lateral
nTPM: 728.6
2053 Male, age 18, unknown 1026.3
2272 Male, age 74, both hemispheres 582.4
2140 Male, age 76, both hemispheres 577.0
Pretectal area
nTPM: 625.5
2407 Male, age 75, both hemispheres 1007.0
2316 Male, age 76, right hemisphere 976.2
2273 Male, age 74, both hemispheres 714.8
2825 Male, age 18, unknown 667.9
2224 Female, age 72, unknown 639.8
1815 Male, age 53, unknown 585.5
1816 Male, age 51, unknown 563.9
2667 Female, age 75, unknown 559.2
1944 Female, age 72, unknown 548.4
1817 Female, age 42, unknown 372.5
2007 Male, age 72, unknown 245.5
Red nucleus
nTPM: 363.8
2503 Female, age 72, unknown 541.5
2725 Female, age 75, unknown 468.3
2823 Male, age 76, right hemisphere 432.2
2769 Male, age 72, unknown 375.6
2588 Male, age 74, left hemisphere 364.8
2227 Male, age 72, unknown 362.5
2584 Male, age 75, left hemisphere 342.8
1865 Male, age 51, unknown 332.8
2785 Male, age 18, unknown 315.6
1821 Female, age 72, unknown 308.1
1904 Male, age 53, unknown 303.8
1954 Female, age 42, unknown 217.8
Substantia nigra
nTPM: 569.6
2699 Male, age 18, unknown 1073.0
1851 Male, age 51, unknown 773.1
2590 Female, age 75, unknown 599.3
2583 Male, age 75, right hemisphere 576.0
2409 Female, age 72, unknown 561.3
2665 Male, age 74, both hemispheres 522.9
1916 Female, age 42, unknown 482.0
1941 Male, age 53, unknown 441.0
1889 Female, age 72, unknown 350.4
2241 Male, age 72, unknown 317.3
Superior colliculus
nTPM: 728.9
1913 Female, age 42, unknown 1128.1
2664 Male, age 75, both hemispheres 1116.9
1995 Male, age 72, unknown 991.1
1796 Male, age 53, unknown 931.2
2087 Female, age 72, unknown 704.1
2587 Male, age 74, left hemisphere 610.5
1839 Male, age 51, unknown 575.5
2261 Male, age 18, unknown 537.2
2668 Female, age 75, unknown 411.7
1895 Male, age 76, right hemisphere 283.0
Ventral tegmental area
nTPM: 597.1
2021 Male, age 53, unknown 959.8
1915 Female, age 42, unknown 813.4
2223 Female, age 72, unknown 527.7
1942 Male, age 51, unknown 446.6
2218 Male, age 76, both hemispheres 419.6
2410 Female, age 72, unknown 415.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

707.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 707.2
Samples: 139

Max nTPM: 2762.4
Min nTPM: 100.8
Std nTPM: 454.8
Median nTPM: 601.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2762.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 2180.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2141.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1975.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1595.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1580.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1556.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1553.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1547.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1442.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1414.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1410.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1407.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1377.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1352.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1329.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1324.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1304.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1252.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1215.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1202.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1180.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1153.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1106.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1080.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1061.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1043.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 1039.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1014.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1005.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 977.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 934.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 933.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 919.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 917.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 904.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 894.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 862.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 853.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 827.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 816.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 791.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 790.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 789.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 784.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 760.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 754.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 747.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 738.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 730.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 722.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 689.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 688.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 687.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 682.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 676.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 661.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 654.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 632.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 631.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 628.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 626.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 626.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 624.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 620.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 610.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 609.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 608.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 607.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 601.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 591.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 563.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 559.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 554.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 546.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 533.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 519.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 514.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 496.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 491.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 490.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 480.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 479.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 466.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 464.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 464.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 460.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 458.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 455.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 451.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 450.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 449.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 443.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 440.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 436.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 431.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 430.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 430.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 427.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 422.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 420.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 419.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 413.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 403.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 401.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 399.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 395.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 391.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 387.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 373.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 373.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 360.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 344.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 341.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 334.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 330.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 328.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 324.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 318.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 311.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 307.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 305.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 291.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 290.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 274.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 245.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 242.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 236.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 236.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 224.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 216.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 209.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 208.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 204.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 195.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 179.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 174.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 155.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 100.8
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

754.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 754.1
FF:10158-103A5 76 years, female 754.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

139.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 139.7
Samples: 4

Max nTPM: 172.8
Min nTPM: 109.4
Sample A Male 132.0
Sample B Male 109.4
Sample C Female 172.8
Sample D Female 144.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.2
74431465 Antisense, RP_060207_02_A08, Mouse strain C57BL/6J (56 days, male) 0.2

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