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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:502.5 nTPM
HPA Brain:177.1 nTPM
GTEx:502.5 nTPM
FANTOM5:237.5 Scaled Tags Per Million
Pig:218.9 nTPM
Mouse:441.0 nTPM
Allen mouse:0.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

177.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 139.1
1870 Female, age 42, unknown 163.3
2666 Male, age 74, left hemisphere 159.0
1827 Male, age 72, unknown 155.5
2828 Female, age 72, unknown 149.1
2019 Male, age 18, unknown 148.4
2219 Male, age 76, both hemispheres 137.5
1833 Male, age 53, unknown 134.8
1830 Male, age 51, unknown 120.3
2411 Female, age 72, unknown 116.6
2586 Male, age 75, left hemisphere 106.8
Dorsal raphe nucleus
nTPM: 136.0
1828 Male, age 53, unknown 150.4
2047 Male, age 72, unknown 143.9
2750 Male, age 76, both hemispheres 136.0
2298 Female, age 72, unknown 133.2
2016 Female, age 72, unknown 116.5
Inferior colliculus
nTPM: 142.6
1890 Male, age 53, unknown 155.0
2849 Male, age 72, unknown 141.1
1848 Female, age 42, unknown 137.5
2097 Female, age 72, unknown 136.7
Median raphe nucleus
nTPM: 177.1
2220 Male, age 76, midline 177.1
Periaquaductal grey, anterior
nTPM: 140.9
1795 Male, age 51, unknown 148.3
1947 Male, age 18, unknown 140.7
2502 Female, age 75, unknown 133.8
Periaquaductal grey, dorsal
nTPM: 127.0
2850 Male, age 76, both hemispheres 155.3
1840 Male, age 53, unknown 131.7
1831 Male, age 72, unknown 123.2
2464 Female, age 72, unknown 97.7
Periaquaductal grey, lateral
nTPM: 121.8
2140 Male, age 76, both hemispheres 131.2
2053 Male, age 18, unknown 120.7
2272 Male, age 74, both hemispheres 113.5
Pretectal area
nTPM: 161.5
1944 Female, age 72, unknown 215.1
2007 Male, age 72, unknown 198.8
1817 Female, age 42, unknown 195.0
1816 Male, age 51, unknown 186.8
2667 Female, age 75, unknown 167.7
1815 Male, age 53, unknown 162.6
2407 Male, age 75, both hemispheres 145.6
2224 Female, age 72, unknown 133.9
2825 Male, age 18, unknown 131.2
2273 Male, age 74, both hemispheres 120.4
2316 Male, age 76, right hemisphere 119.0
Red nucleus
nTPM: 139.6
2785 Male, age 18, unknown 167.7
2725 Female, age 75, unknown 164.8
2584 Male, age 75, left hemisphere 147.7
2823 Male, age 76, right hemisphere 142.6
1865 Male, age 51, unknown 141.9
2503 Female, age 72, unknown 140.1
2588 Male, age 74, left hemisphere 137.2
1821 Female, age 72, unknown 136.6
1954 Female, age 42, unknown 135.1
2769 Male, age 72, unknown 125.7
2227 Male, age 72, unknown 123.4
1904 Male, age 53, unknown 113.1
Substantia nigra
nTPM: 168.0
1916 Female, age 42, unknown 238.4
1889 Female, age 72, unknown 202.0
2665 Male, age 74, both hemispheres 175.9
2241 Male, age 72, unknown 174.2
1941 Male, age 53, unknown 170.9
1851 Male, age 51, unknown 162.3
2409 Female, age 72, unknown 156.9
2699 Male, age 18, unknown 147.4
2590 Female, age 75, unknown 128.6
2583 Male, age 75, right hemisphere 123.9
Superior colliculus
nTPM: 134.8
2087 Female, age 72, unknown 168.8
1796 Male, age 53, unknown 151.2
2668 Female, age 75, unknown 143.5
1895 Male, age 76, right hemisphere 142.0
2261 Male, age 18, unknown 140.0
2587 Male, age 74, left hemisphere 139.4
1913 Female, age 42, unknown 127.9
1839 Male, age 51, unknown 117.0
2664 Male, age 75, both hemispheres 111.1
1995 Male, age 72, unknown 107.4
Ventral tegmental area
nTPM: 144.9
1915 Female, age 42, unknown 167.1
2218 Male, age 76, both hemispheres 162.4
1942 Male, age 51, unknown 150.6
2223 Female, age 72, unknown 148.0
2410 Female, age 72, unknown 123.4
2021 Male, age 53, unknown 118.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

502.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 502.5
Samples: 139

Max nTPM: 950.5
Min nTPM: 289.0
Std nTPM: 130.8
Median nTPM: 476.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 950.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 903.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 857.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 803.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 801.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 791.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 764.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 735.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 733.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 731.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 722.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 698.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 690.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 689.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 687.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 685.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 679.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 666.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 666.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 660.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 656.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 651.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 646.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 616.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 614.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 613.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 609.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 595.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 592.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 581.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 581.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 580.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 578.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 576.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 573.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 571.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 562.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 558.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 547.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 546.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 543.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 542.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 536.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 536.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 532.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 531.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 531.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 531.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 530.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 528.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 526.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 524.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 518.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 515.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 513.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 510.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 508.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 507.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 507.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 506.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 506.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 502.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 500.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 499.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 493.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 490.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 489.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 487.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 481.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 476.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 475.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 474.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 474.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 474.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 472.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 466.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 463.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 461.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 460.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 459.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 454.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 453.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 445.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 440.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 437.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 436.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 436.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 436.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 430.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 429.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 429.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 429.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 427.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 425.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 424.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 418.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 417.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 416.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 415.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 415.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 414.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 413.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 413.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 411.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 408.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 404.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 401.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 400.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 399.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 398.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 398.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 394.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 394.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 394.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 388.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 386.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 384.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 377.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 375.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 375.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 374.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 367.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 366.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 364.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 363.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 362.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 350.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 345.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 343.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 341.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 338.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 338.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 331.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 324.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 319.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 318.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 297.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 289.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 289.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

237.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 237.5
FF:10158-103A5 76 years, female 237.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

218.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 187.2
Samples: 4

Max nTPM: 271.8
Min nTPM: 127.8
Sample A Female 271.8
Sample B Female 185.4
Sample C Male 163.6
Sample D Male 127.8
Midbrain
nTPM: 203.0
Samples: 4

Max nTPM: 230.6
Min nTPM: 182.3
Sample A Female 230.6
Sample B Female 202.3
Sample C Male 196.7
Sample D Male 182.3
Periaqueductal gray
nTPM: 158.6
Samples: 3

Max nTPM: 175.2
Min nTPM: 138.0
Sample B Female 175.2
Sample C Male 162.6
Sample D Male 138.0
Superior colliculi
nTPM: 219.0
Samples: 4

Max nTPM: 267.9
Min nTPM: 184.0
Sample A Female 267.9
Sample B Female 191.3
Sample C Male 232.6
Sample D Male 184.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

441.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 441.0
Samples: 4

Max nTPM: 472.7
Min nTPM: 389.1
Sample A Male 467.0
Sample B Male 435.1
Sample C Female 389.1
Sample D Female 472.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.9
68076547 Antisense, RP_040923_02_F08, Mouse strain C57BL/6J (56 days, male) 1.5
70918976 Antisense, RP_050712_04_H06, Mouse strain C57BL/6J (56 days, male) 0.4

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