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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:155.3 nTPM
HPA Brain:398.8 nTPM
GTEx:155.3 nTPM
FANTOM5:138.5 Scaled Tags Per Million
Pig:344.0 nTPM
Mouse:444.8 nTPM
Allen mouse:18.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

398.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 306.0
2666 Male, age 74, left hemisphere 398.0
1827 Male, age 72, unknown 373.4
2411 Female, age 72, unknown 335.5
2019 Male, age 18, unknown 316.8
2219 Male, age 76, both hemispheres 307.7
2586 Male, age 75, left hemisphere 287.5
2828 Female, age 72, unknown 275.0
1870 Female, age 42, unknown 274.1
1833 Male, age 53, unknown 254.4
1830 Male, age 51, unknown 237.6
Dorsal raphe nucleus
nTPM: 323.6
2298 Female, age 72, unknown 403.6
2047 Male, age 72, unknown 364.2
1828 Male, age 53, unknown 329.6
2750 Male, age 76, both hemispheres 325.6
2016 Female, age 72, unknown 194.7
Inferior colliculus
nTPM: 276.1
2097 Female, age 72, unknown 340.0
1848 Female, age 42, unknown 281.9
2849 Male, age 72, unknown 242.1
1890 Male, age 53, unknown 240.3
Median raphe nucleus
nTPM: 385.7
2220 Male, age 76, midline 385.7
Periaquaductal grey, anterior
nTPM: 341.6
1947 Male, age 18, unknown 383.8
1795 Male, age 51, unknown 347.4
2502 Female, age 75, unknown 293.5
Periaquaductal grey, dorsal
nTPM: 237.0
1840 Male, age 53, unknown 264.5
1831 Male, age 72, unknown 244.6
2464 Female, age 72, unknown 220.9
2850 Male, age 76, both hemispheres 218.0
Periaquaductal grey, lateral
nTPM: 215.7
2053 Male, age 18, unknown 237.7
2272 Male, age 74, both hemispheres 214.6
2140 Male, age 76, both hemispheres 194.8
Pretectal area
nTPM: 335.8
1816 Male, age 51, unknown 488.4
1944 Female, age 72, unknown 474.0
2007 Male, age 72, unknown 459.0
1817 Female, age 42, unknown 435.8
1815 Male, age 53, unknown 360.1
2224 Female, age 72, unknown 305.5
2667 Female, age 75, unknown 275.0
2825 Male, age 18, unknown 256.2
2407 Male, age 75, both hemispheres 243.3
2316 Male, age 76, right hemisphere 207.9
2273 Male, age 74, both hemispheres 188.7
Red nucleus
nTPM: 252.9
1821 Female, age 72, unknown 329.3
2725 Female, age 75, unknown 303.5
2584 Male, age 75, left hemisphere 292.0
2785 Male, age 18, unknown 277.0
2588 Male, age 74, left hemisphere 271.9
1954 Female, age 42, unknown 254.0
2823 Male, age 76, right hemisphere 223.6
2227 Male, age 72, unknown 218.3
2769 Male, age 72, unknown 217.7
1865 Male, age 51, unknown 217.3
1904 Male, age 53, unknown 216.2
2503 Female, age 72, unknown 214.3
Substantia nigra
nTPM: 398.8
1916 Female, age 42, unknown 557.0
1941 Male, age 53, unknown 537.0
1889 Female, age 72, unknown 441.4
1851 Male, age 51, unknown 428.9
2241 Male, age 72, unknown 413.0
2665 Male, age 74, both hemispheres 380.8
2409 Female, age 72, unknown 373.4
2590 Female, age 75, unknown 288.3
2699 Male, age 18, unknown 288.1
2583 Male, age 75, right hemisphere 280.4
Superior colliculus
nTPM: 289.7
2668 Female, age 75, unknown 417.3
2087 Female, age 72, unknown 382.9
1796 Male, age 53, unknown 324.2
2261 Male, age 18, unknown 324.1
1895 Male, age 76, right hemisphere 316.0
1839 Male, age 51, unknown 266.4
2587 Male, age 74, left hemisphere 236.8
2664 Male, age 75, both hemispheres 228.9
1913 Female, age 42, unknown 216.7
1995 Male, age 72, unknown 183.4
Ventral tegmental area
nTPM: 338.2
2218 Male, age 76, both hemispheres 421.3
2410 Female, age 72, unknown 421.1
1915 Female, age 42, unknown 390.2
1942 Male, age 51, unknown 293.4
2223 Female, age 72, unknown 260.5
2021 Male, age 53, unknown 242.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

155.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 155.3
Samples: 139

Max nTPM: 754.2
Min nTPM: 37.4
Std nTPM: 115.8
Median nTPM: 112.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 754.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 696.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 498.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 486.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 391.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 382.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 366.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 355.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 344.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 306.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 306.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 303.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 297.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 296.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 294.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 288.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 281.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 276.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 271.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 271.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 266.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 265.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 258.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 255.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 239.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 236.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 230.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 229.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 227.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 225.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 217.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 210.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 208.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 204.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 199.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 197.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 187.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 184.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 181.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 180.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 176.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 174.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 174.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 173.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 162.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 161.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 161.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 160.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 159.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 159.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 157.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 155.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 155.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 153.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 151.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 148.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 147.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 146.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 146.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 137.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 133.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 133.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 127.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 126.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 116.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 116.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 113.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 113.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 112.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 112.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 112.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 108.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 107.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 107.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 105.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 104.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 104.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 101.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 101.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 99.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 98.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 93.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 93.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 92.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 92.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 91.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 90.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 90.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 89.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 89.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 89.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 89.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 88.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 88.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 88.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 87.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 85.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 83.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 82.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 81.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 81.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 80.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 79.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 79.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 78.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 77.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 75.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 75.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 74.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 72.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 72.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 72.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 71.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 69.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 69.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 68.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 67.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 66.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 65.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 65.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 64.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 63.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 63.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 61.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 60.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 60.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 59.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 57.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 57.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 56.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 53.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 53.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 52.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 52.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 52.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 50.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 47.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 38.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 37.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

138.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 138.5
FF:10158-103A5 76 years, female 138.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

344.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 295.3
Samples: 4

Max nTPM: 444.4
Min nTPM: 117.5
Sample A Female 444.4
Sample B Female 210.9
Sample C Male 408.4
Sample D Male 117.5
Midbrain
nTPM: 324.0
Samples: 4

Max nTPM: 552.4
Min nTPM: 139.5
Sample A Female 139.5
Sample B Female 233.8
Sample C Male 552.4
Sample D Male 370.1
Periaqueductal gray
nTPM: 237.5
Samples: 3

Max nTPM: 307.9
Min nTPM: 194.8
Sample B Female 209.9
Sample C Male 307.9
Sample D Male 194.8
Superior colliculi
nTPM: 344.0
Samples: 4

Max nTPM: 527.2
Min nTPM: 165.3
Sample A Female 362.8
Sample B Female 165.3
Sample C Male 527.2
Sample D Male 320.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

444.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 444.8
Samples: 4

Max nTPM: 452.1
Min nTPM: 434.0
Sample A Male 434.0
Sample B Male 444.4
Sample C Female 448.7
Sample D Female 452.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

18.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 18.0
68443009 Antisense, RP_050111_01_B11, Mouse strain C57BL/6J (56 days, male) 23.1
1124 Antisense, RP_Baylor_103127, Mouse strain C57BL/6J (56 days, male) 12.8
1125 Antisense, RP_Baylor_103127, Mouse strain C57BL/6J (56 days, male) 9.5

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