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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:218.0 nTPM
HPA Brain:270.0 nTPM
GTEx:218.0 nTPM
FANTOM5:474.2 Scaled Tags Per Million
Pig:197.4 nTPM
Mouse:75.9 nTPM
Allen mouse:4.3 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

270.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 216.8
2219 Male, age 76, both hemispheres 282.4
2586 Male, age 75, left hemisphere 246.2
2411 Female, age 72, unknown 237.8
1830 Male, age 51, unknown 237.6
1833 Male, age 53, unknown 222.7
2019 Male, age 18, unknown 212.9
1870 Female, age 42, unknown 211.3
2828 Female, age 72, unknown 198.7
1827 Male, age 72, unknown 161.6
2666 Male, age 74, left hemisphere 157.2
Dorsal raphe nucleus
nTPM: 163.9
2750 Male, age 76, both hemispheres 237.4
2016 Female, age 72, unknown 181.8
1828 Male, age 53, unknown 166.4
2047 Male, age 72, unknown 126.3
2298 Female, age 72, unknown 107.6
Inferior colliculus
nTPM: 158.7
1890 Male, age 53, unknown 185.9
1848 Female, age 42, unknown 151.6
2849 Male, age 72, unknown 150.5
2097 Female, age 72, unknown 146.9
Median raphe nucleus
nTPM: 102.0
2220 Male, age 76, midline 102.0
Periaquaductal grey, anterior
nTPM: 150.0
2502 Female, age 75, unknown 180.3
1947 Male, age 18, unknown 139.3
1795 Male, age 51, unknown 130.4
Periaquaductal grey, dorsal
nTPM: 115.5
2464 Female, age 72, unknown 169.9
1831 Male, age 72, unknown 116.0
1840 Male, age 53, unknown 105.0
2850 Male, age 76, both hemispheres 70.9
Periaquaductal grey, lateral
nTPM: 121.7
2272 Male, age 74, both hemispheres 139.3
2053 Male, age 18, unknown 139.0
2140 Male, age 76, both hemispheres 86.9
Pretectal area
nTPM: 154.4
2316 Male, age 76, right hemisphere 227.6
1815 Male, age 53, unknown 201.0
1817 Female, age 42, unknown 180.1
2007 Male, age 72, unknown 178.9
2407 Male, age 75, both hemispheres 169.4
2667 Female, age 75, unknown 143.6
2825 Male, age 18, unknown 143.6
2224 Female, age 72, unknown 124.0
2273 Male, age 74, both hemispheres 114.4
1816 Male, age 51, unknown 111.8
1944 Female, age 72, unknown 103.8
Red nucleus
nTPM: 270.0
2769 Male, age 72, unknown 318.2
2503 Female, age 72, unknown 316.6
2227 Male, age 72, unknown 316.4
1904 Male, age 53, unknown 311.8
1865 Male, age 51, unknown 297.3
2823 Male, age 76, right hemisphere 290.8
2588 Male, age 74, left hemisphere 269.8
1821 Female, age 72, unknown 269.7
2785 Male, age 18, unknown 258.3
1954 Female, age 42, unknown 241.1
2584 Male, age 75, left hemisphere 191.3
2725 Female, age 75, unknown 159.0
Substantia nigra
nTPM: 169.6
2699 Male, age 18, unknown 235.3
1851 Male, age 51, unknown 201.9
2583 Male, age 75, right hemisphere 192.0
2665 Male, age 74, both hemispheres 187.1
2409 Female, age 72, unknown 179.6
1889 Female, age 72, unknown 167.8
2590 Female, age 75, unknown 159.9
1916 Female, age 42, unknown 138.1
1941 Male, age 53, unknown 117.4
2241 Male, age 72, unknown 116.5
Superior colliculus
nTPM: 193.3
2668 Female, age 75, unknown 276.3
1995 Male, age 72, unknown 253.8
1895 Male, age 76, right hemisphere 235.3
1913 Female, age 42, unknown 219.1
1839 Male, age 51, unknown 192.2
2664 Male, age 75, both hemispheres 184.1
2587 Male, age 74, left hemisphere 180.1
1796 Male, age 53, unknown 147.3
2261 Male, age 18, unknown 128.5
2087 Female, age 72, unknown 116.0
Ventral tegmental area
nTPM: 167.0
2410 Female, age 72, unknown 203.1
2223 Female, age 72, unknown 192.8
1915 Female, age 42, unknown 164.4
1942 Male, age 51, unknown 160.5
2021 Male, age 53, unknown 151.1
2218 Male, age 76, both hemispheres 130.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

218.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 218.0
Samples: 139

Max nTPM: 483.4
Min nTPM: 41.8
Std nTPM: 85.9
Median nTPM: 202.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 483.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 427.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 423.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 408.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 401.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 385.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 380.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 374.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 359.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 349.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 348.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 345.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 342.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 339.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 334.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 333.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 332.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 331.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 329.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 328.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 323.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 312.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 310.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 307.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 301.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 300.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 300.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 298.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 296.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 296.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 294.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 292.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 290.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 290.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 284.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 273.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 270.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 266.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 263.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 261.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 255.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 255.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 254.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 254.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 251.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 246.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 242.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 238.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 236.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 236.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 233.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 232.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 232.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 229.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 229.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 226.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 214.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 214.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 212.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 209.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 209.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 208.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 207.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 207.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 207.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 206.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 204.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 203.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 203.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 202.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 199.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 199.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 199.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 197.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 195.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 194.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 191.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 189.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 189.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 189.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 187.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 187.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 186.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 186.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 185.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 183.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 182.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 180.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 179.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 179.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 176.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 175.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 171.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 170.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 168.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 167.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 167.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 167.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 167.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 166.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 162.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 161.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 161.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 160.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 159.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 158.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 158.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 152.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 151.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 151.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 147.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 147.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 144.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 142.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 141.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 141.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 138.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 138.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 136.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 135.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 132.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 130.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 123.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 118.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 113.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 110.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 108.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 106.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 101.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 99.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 96.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 91.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 91.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 90.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 89.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 78.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 75.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 72.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 41.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

474.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 474.2
FF:10158-103A5 76 years, female 474.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

197.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 197.4
Samples: 4

Max nTPM: 264.1
Min nTPM: 141.4
Sample A Female 232.2
Sample B Female 141.4
Sample C Male 152.0
Sample D Male 264.1
Midbrain
nTPM: 193.5
Samples: 4

Max nTPM: 271.4
Min nTPM: 141.6
Sample A Female 271.4
Sample B Female 213.2
Sample C Male 141.6
Sample D Male 147.8
Periaqueductal gray
nTPM: 146.6
Samples: 3

Max nTPM: 184.5
Min nTPM: 123.8
Sample B Female 184.5
Sample C Male 123.8
Sample D Male 131.4
Superior colliculi
nTPM: 166.8
Samples: 4

Max nTPM: 217.7
Min nTPM: 93.2
Sample A Female 217.7
Sample B Female 93.2
Sample C Male 170.2
Sample D Male 185.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

75.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 75.9
Samples: 4

Max nTPM: 85.3
Min nTPM: 65.8
Sample A Male 85.3
Sample B Male 65.8
Sample C Female 69.3
Sample D Female 83.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.3
70437828 Antisense, RP_050614_03_A03, Mouse strain C57BL/6J (56 days, male) 4.3

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