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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:156.5 nTPM
HPA Brain:149.6 nTPM
GTEx:156.5 nTPM
FANTOM5:40.0 Scaled Tags Per Million
Pig:244.1 nTPM
Mouse:158.1 nTPM
Allen mouse:4.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

149.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 126.1
2666 Male, age 74, left hemisphere 184.2
1827 Male, age 72, unknown 138.1
2411 Female, age 72, unknown 136.1
2019 Male, age 18, unknown 130.0
2828 Female, age 72, unknown 120.2
1833 Male, age 53, unknown 117.8
2586 Male, age 75, left hemisphere 117.3
1870 Female, age 42, unknown 111.5
1830 Male, age 51, unknown 107.6
2219 Male, age 76, both hemispheres 98.1
Dorsal raphe nucleus
nTPM: 140.8
2298 Female, age 72, unknown 172.6
2047 Male, age 72, unknown 153.3
2750 Male, age 76, both hemispheres 132.1
1828 Male, age 53, unknown 131.6
2016 Female, age 72, unknown 114.3
Inferior colliculus
nTPM: 99.9
1848 Female, age 42, unknown 104.1
2849 Male, age 72, unknown 103.8
2097 Female, age 72, unknown 101.1
1890 Male, age 53, unknown 90.4
Median raphe nucleus
nTPM: 149.6
2220 Male, age 76, midline 149.6
Periaquaductal grey, anterior
nTPM: 120.0
1795 Male, age 51, unknown 135.3
1947 Male, age 18, unknown 123.8
2502 Female, age 75, unknown 101.0
Periaquaductal grey, dorsal
nTPM: 103.1
1840 Male, age 53, unknown 107.3
2850 Male, age 76, both hemispheres 105.2
1831 Male, age 72, unknown 100.1
2464 Female, age 72, unknown 100.0
Periaquaductal grey, lateral
nTPM: 100.2
2272 Male, age 74, both hemispheres 109.9
2053 Male, age 18, unknown 100.6
2140 Male, age 76, both hemispheres 90.1
Pretectal area
nTPM: 124.2
2007 Male, age 72, unknown 158.2
1817 Female, age 42, unknown 155.3
1816 Male, age 51, unknown 143.7
1815 Male, age 53, unknown 139.6
1944 Female, age 72, unknown 137.0
2224 Female, age 72, unknown 120.3
2667 Female, age 75, unknown 110.7
2825 Male, age 18, unknown 109.9
2273 Male, age 74, both hemispheres 105.1
2407 Male, age 75, both hemispheres 101.9
2316 Male, age 76, right hemisphere 84.0
Red nucleus
nTPM: 104.5
1821 Female, age 72, unknown 132.0
2725 Female, age 75, unknown 120.1
2785 Male, age 18, unknown 112.7
2584 Male, age 75, left hemisphere 108.5
2588 Male, age 74, left hemisphere 107.6
2503 Female, age 72, unknown 105.1
1954 Female, age 42, unknown 102.2
2769 Male, age 72, unknown 97.0
2227 Male, age 72, unknown 95.9
2823 Male, age 76, right hemisphere 92.8
1904 Male, age 53, unknown 91.7
1865 Male, age 51, unknown 88.2
Substantia nigra
nTPM: 147.7
1916 Female, age 42, unknown 199.5
1941 Male, age 53, unknown 175.9
1851 Male, age 51, unknown 172.2
2665 Male, age 74, both hemispheres 148.9
1889 Female, age 72, unknown 146.2
2241 Male, age 72, unknown 139.7
2699 Male, age 18, unknown 133.1
2409 Female, age 72, unknown 124.2
2590 Female, age 75, unknown 119.9
2583 Male, age 75, right hemisphere 117.0
Superior colliculus
nTPM: 110.8
2668 Female, age 75, unknown 149.1
2087 Female, age 72, unknown 126.7
1796 Male, age 53, unknown 122.0
2587 Male, age 74, left hemisphere 117.3
2261 Male, age 18, unknown 111.7
1839 Male, age 51, unknown 106.9
2664 Male, age 75, both hemispheres 100.1
1895 Male, age 76, right hemisphere 97.5
1913 Female, age 42, unknown 94.1
1995 Male, age 72, unknown 82.3
Ventral tegmental area
nTPM: 129.9
1915 Female, age 42, unknown 157.6
2410 Female, age 72, unknown 156.2
2218 Male, age 76, both hemispheres 130.3
1942 Male, age 51, unknown 112.8
2021 Male, age 53, unknown 111.4
2223 Female, age 72, unknown 111.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

156.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 156.5
Samples: 139

Max nTPM: 313.0
Min nTPM: 93.4
Std nTPM: 36.7
Median nTPM: 148.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 313.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 252.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 236.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 235.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 232.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 231.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 230.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 220.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 217.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 216.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 213.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 213.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 211.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 209.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 209.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 206.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 205.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 204.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 203.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 202.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 199.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 196.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 196.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 192.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 189.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 186.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 185.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 183.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 183.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 182.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 179.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 177.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 177.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 174.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 173.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 173.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 173.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 172.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 171.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 171.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 170.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 169.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 168.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 167.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 167.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 167.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 166.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 166.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 166.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 166.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 166.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 165.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 163.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 163.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 162.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 161.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 161.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 161.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 159.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 159.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 158.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 157.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 157.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 153.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 153.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 152.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 151.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 150.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 149.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 148.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 148.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 148.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 146.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 145.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 143.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 143.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 142.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 142.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 141.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 140.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 140.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 139.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 139.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 139.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 139.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 138.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 138.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 138.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 138.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 137.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 137.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 136.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 136.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 135.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 135.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 134.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 134.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 134.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 133.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 133.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 132.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 132.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 132.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 131.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 131.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 130.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 130.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 129.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 129.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 129.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 128.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 128.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 127.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 125.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 125.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 124.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 123.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 123.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 122.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 121.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 120.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 120.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 120.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 119.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 117.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 116.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 114.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 113.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 113.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 112.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 108.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 104.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 101.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 100.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 99.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 98.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 97.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 95.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 93.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

40.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 40.0
FF:10158-103A5 76 years, female 40.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

244.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 221.8
Samples: 4

Max nTPM: 285.1
Min nTPM: 185.4
Sample A Female 285.1
Sample B Female 197.4
Sample C Male 219.1
Sample D Male 185.4
Midbrain
nTPM: 227.7
Samples: 4

Max nTPM: 297.5
Min nTPM: 191.6
Sample A Female 297.5
Sample B Female 210.1
Sample C Male 211.6
Sample D Male 191.6
Periaqueductal gray
nTPM: 192.2
Samples: 3

Max nTPM: 212.3
Min nTPM: 176.6
Sample B Female 187.7
Sample C Male 212.3
Sample D Male 176.6
Superior colliculi
nTPM: 244.2
Samples: 4

Max nTPM: 291.4
Min nTPM: 214.4
Sample A Female 291.4
Sample B Female 246.9
Sample C Male 223.9
Sample D Male 214.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

158.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 158.1
Samples: 4

Max nTPM: 165.0
Min nTPM: 153.4
Sample A Male 155.2
Sample B Male 153.4
Sample C Female 158.9
Sample D Female 165.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.9
79544798 Antisense, RP_071018_01_C08, Mouse strain C57BL/6J (56 days, male) 4.9

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