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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:217.2 nTPM
HPA Brain:79.2 nTPM
GTEx:217.2 nTPM
FANTOM5:497.0 Scaled Tags Per Million
Pig:738.1 nTPM
Mouse:994.2 nTPM
Allen mouse:6.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

79.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 60.6
2019 Male, age 18, unknown 76.4
1827 Male, age 72, unknown 72.7
2411 Female, age 72, unknown 69.5
1870 Female, age 42, unknown 62.7
2586 Male, age 75, left hemisphere 59.5
2828 Female, age 72, unknown 55.4
2666 Male, age 74, left hemisphere 53.6
1833 Male, age 53, unknown 53.3
1830 Male, age 51, unknown 52.1
2219 Male, age 76, both hemispheres 50.3
Dorsal raphe nucleus
nTPM: 65.3
2298 Female, age 72, unknown 87.1
2047 Male, age 72, unknown 64.2
1828 Male, age 53, unknown 63.1
2750 Male, age 76, both hemispheres 60.1
2016 Female, age 72, unknown 51.9
Inferior colliculus
nTPM: 79.2
2097 Female, age 72, unknown 106.2
1890 Male, age 53, unknown 85.8
1848 Female, age 42, unknown 67.7
2849 Male, age 72, unknown 57.3
Median raphe nucleus
nTPM: 49.6
2220 Male, age 76, midline 49.6
Periaquaductal grey, anterior
nTPM: 65.2
1947 Male, age 18, unknown 71.9
1795 Male, age 51, unknown 63.1
2502 Female, age 75, unknown 60.5
Periaquaductal grey, dorsal
nTPM: 54.1
1840 Male, age 53, unknown 58.8
2464 Female, age 72, unknown 56.9
1831 Male, age 72, unknown 53.4
2850 Male, age 76, both hemispheres 47.2
Periaquaductal grey, lateral
nTPM: 55.1
2053 Male, age 18, unknown 63.2
2272 Male, age 74, both hemispheres 57.9
2140 Male, age 76, both hemispheres 44.0
Pretectal area
nTPM: 75.7
1816 Male, age 51, unknown 105.7
2007 Male, age 72, unknown 105.5
1817 Female, age 42, unknown 92.8
1944 Female, age 72, unknown 85.9
1815 Male, age 53, unknown 76.7
2667 Female, age 75, unknown 70.4
2224 Female, age 72, unknown 67.1
2273 Male, age 74, both hemispheres 66.1
2316 Male, age 76, right hemisphere 56.4
2825 Male, age 18, unknown 53.6
2407 Male, age 75, both hemispheres 52.9
Red nucleus
nTPM: 67.4
1821 Female, age 72, unknown 91.9
2725 Female, age 75, unknown 75.5
2503 Female, age 72, unknown 72.2
2785 Male, age 18, unknown 71.0
2588 Male, age 74, left hemisphere 70.4
1865 Male, age 51, unknown 64.0
2769 Male, age 72, unknown 63.6
2584 Male, age 75, left hemisphere 63.5
2227 Male, age 72, unknown 63.0
2823 Male, age 76, right hemisphere 61.2
1954 Female, age 42, unknown 56.3
1904 Male, age 53, unknown 55.7
Substantia nigra
nTPM: 70.5
1889 Female, age 72, unknown 89.1
1941 Male, age 53, unknown 81.5
1851 Male, age 51, unknown 75.9
1916 Female, age 42, unknown 74.0
2241 Male, age 72, unknown 73.3
2665 Male, age 74, both hemispheres 71.1
2409 Female, age 72, unknown 66.3
2590 Female, age 75, unknown 65.8
2583 Male, age 75, right hemisphere 58.9
2699 Male, age 18, unknown 49.8
Superior colliculus
nTPM: 66.0
2587 Male, age 74, left hemisphere 77.2
2087 Female, age 72, unknown 75.1
2261 Male, age 18, unknown 72.2
1796 Male, age 53, unknown 71.1
2668 Female, age 75, unknown 68.9
1895 Male, age 76, right hemisphere 68.8
1913 Female, age 42, unknown 61.7
1839 Male, age 51, unknown 60.1
1995 Male, age 72, unknown 54.2
2664 Male, age 75, both hemispheres 51.1
Ventral tegmental area
nTPM: 65.2
2410 Female, age 72, unknown 73.7
2223 Female, age 72, unknown 73.1
1915 Female, age 42, unknown 72.3
2218 Male, age 76, both hemispheres 61.1
1942 Male, age 51, unknown 55.6
2021 Male, age 53, unknown 55.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

217.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 217.2
Samples: 139

Max nTPM: 620.8
Min nTPM: 108.0
Std nTPM: 68.1
Median nTPM: 203.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 620.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 446.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 399.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 371.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 356.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 351.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 331.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 330.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 328.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 319.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 318.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 317.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 312.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 311.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 308.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 298.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 291.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 280.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 280.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 276.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 275.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 265.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 264.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 263.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 260.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 260.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 258.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 257.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 256.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 256.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 255.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 248.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 243.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 242.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 242.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 241.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 240.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 238.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 236.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 235.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 234.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 233.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 232.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 228.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 228.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 227.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 226.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 224.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 223.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 223.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 221.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 220.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 220.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 219.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 218.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 216.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 215.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 214.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 212.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 210.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 209.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 209.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 208.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 208.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 207.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 207.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 204.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 204.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 203.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 203.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 203.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 202.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 201.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 200.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 199.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 198.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 197.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 196.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 196.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 195.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 195.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 194.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 194.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 193.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 191.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 191.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 191.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 188.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 187.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 186.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 186.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 186.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 186.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 186.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 185.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 184.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 182.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 182.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 181.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 181.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 180.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 179.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 176.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 176.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 175.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 174.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 174.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 170.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 170.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 169.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 169.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 169.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 167.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 166.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 166.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 164.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 162.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 160.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 160.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 154.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 153.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 150.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 148.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 147.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 147.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 147.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 147.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 146.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 144.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 142.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 139.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 138.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 138.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 137.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 132.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 128.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 127.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 112.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 108.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

497.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 497.0
FF:10158-103A5 76 years, female 497.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

738.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 489.0
Samples: 4

Max nTPM: 691.2
Min nTPM: 359.2
Sample A Female 691.2
Sample B Female 435.4
Sample C Male 470.0
Sample D Male 359.2
Midbrain
nTPM: 599.5
Samples: 4

Max nTPM: 725.5
Min nTPM: 509.0
Sample A Female 570.6
Sample B Female 509.0
Sample C Male 725.5
Sample D Male 593.0
Periaqueductal gray
nTPM: 398.5
Samples: 3

Max nTPM: 440.6
Min nTPM: 353.0
Sample B Female 401.8
Sample C Male 440.6
Sample D Male 353.0
Superior colliculi
nTPM: 738.1
Samples: 4

Max nTPM: 868.2
Min nTPM: 594.0
Sample A Female 828.5
Sample B Female 661.8
Sample C Male 868.2
Sample D Male 594.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

994.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 994.2
Samples: 4

Max nTPM: 1013.1
Min nTPM: 976.2
Sample A Male 1013.1
Sample B Male 998.3
Sample C Female 976.2
Sample D Female 989.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

6.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.5
69782139 Antisense, RP_050505_02_D07, Mouse strain C57BL/6J (56 days, male) 6.5

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