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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:782.5 nTPM
HPA Brain:686.6 nTPM
GTEx:782.5 nTPM
FANTOM5:3790.5 Scaled Tags Per Million
Pig:2005.7 nTPM
Mouse:328.7 nTPM
Allen mouse:15.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

686.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 518.2
2411 Female, age 72, unknown 775.1
1830 Male, age 51, unknown 751.8
1870 Female, age 42, unknown 678.5
1833 Male, age 53, unknown 667.1
2019 Male, age 18, unknown 577.7
2828 Female, age 72, unknown 484.6
2219 Male, age 76, both hemispheres 458.4
1827 Male, age 72, unknown 358.9
2666 Male, age 74, left hemisphere 272.1
2586 Male, age 75, left hemisphere 157.8
Dorsal raphe nucleus
nTPM: 417.2
2750 Male, age 76, both hemispheres 804.9
2016 Female, age 72, unknown 403.4
1828 Male, age 53, unknown 357.5
2298 Female, age 72, unknown 262.7
2047 Male, age 72, unknown 257.4
Inferior colliculus
nTPM: 388.9
1890 Male, age 53, unknown 445.9
2849 Male, age 72, unknown 406.7
1848 Female, age 42, unknown 393.6
2097 Female, age 72, unknown 309.2
Median raphe nucleus
nTPM: 471.9
2220 Male, age 76, midline 471.9
Periaquaductal grey, anterior
nTPM: 364.1
2502 Female, age 75, unknown 535.9
1947 Male, age 18, unknown 319.7
1795 Male, age 51, unknown 236.6
Periaquaductal grey, dorsal
nTPM: 322.4
2464 Female, age 72, unknown 397.8
1831 Male, age 72, unknown 336.5
2850 Male, age 76, both hemispheres 329.5
1840 Male, age 53, unknown 225.6
Periaquaductal grey, lateral
nTPM: 372.7
2272 Male, age 74, both hemispheres 471.1
2053 Male, age 18, unknown 353.3
2140 Male, age 76, both hemispheres 293.8
Pretectal area
nTPM: 414.6
2667 Female, age 75, unknown 601.2
1815 Male, age 53, unknown 541.9
1817 Female, age 42, unknown 475.7
2316 Male, age 76, right hemisphere 464.8
2273 Male, age 74, both hemispheres 437.0
2407 Male, age 75, both hemispheres 403.7
2007 Male, age 72, unknown 384.4
2825 Male, age 18, unknown 367.1
1944 Female, age 72, unknown 330.3
2224 Female, age 72, unknown 323.5
1816 Male, age 51, unknown 231.2
Red nucleus
nTPM: 686.6
1865 Male, age 51, unknown 1008.7
1821 Female, age 72, unknown 907.9
2823 Male, age 76, right hemisphere 881.1
1904 Male, age 53, unknown 790.1
2503 Female, age 72, unknown 757.0
2227 Male, age 72, unknown 700.6
2769 Male, age 72, unknown 690.8
2785 Male, age 18, unknown 689.9
1954 Female, age 42, unknown 680.7
2584 Male, age 75, left hemisphere 424.8
2588 Male, age 74, left hemisphere 421.1
2725 Female, age 75, unknown 285.7
Substantia nigra
nTPM: 467.0
2699 Male, age 18, unknown 647.3
2409 Female, age 72, unknown 582.6
2590 Female, age 75, unknown 537.3
1851 Male, age 51, unknown 532.9
1889 Female, age 72, unknown 520.8
2241 Male, age 72, unknown 447.9
2583 Male, age 75, right hemisphere 390.2
1916 Female, age 42, unknown 365.3
2665 Male, age 74, both hemispheres 325.2
1941 Male, age 53, unknown 320.7
Superior colliculus
nTPM: 463.7
1913 Female, age 42, unknown 707.2
1995 Male, age 72, unknown 677.2
2587 Male, age 74, left hemisphere 619.8
1895 Male, age 76, right hemisphere 615.0
1839 Male, age 51, unknown 494.6
1796 Male, age 53, unknown 364.3
2668 Female, age 75, unknown 351.8
2087 Female, age 72, unknown 348.2
2261 Male, age 18, unknown 279.3
2664 Male, age 75, both hemispheres 179.3
Ventral tegmental area
nTPM: 534.7
2223 Female, age 72, unknown 708.1
2410 Female, age 72, unknown 649.7
2218 Male, age 76, both hemispheres 549.5
2021 Male, age 53, unknown 478.3
1915 Female, age 42, unknown 432.8
1942 Male, age 51, unknown 390.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

782.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 782.5
Samples: 139

Max nTPM: 2359.4
Min nTPM: 252.6
Std nTPM: 337.9
Median nTPM: 732.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 2359.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2061.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1583.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1542.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1498.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1486.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1456.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1448.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1341.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1321.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1293.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1273.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1264.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1255.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1237.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1224.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1194.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1183.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1172.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1164.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1156.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1082.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1073.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1051.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1050.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 1032.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 981.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 956.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 933.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 930.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 928.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 925.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 921.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 920.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 916.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 905.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 902.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 901.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 900.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 877.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 875.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 875.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 860.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 857.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 852.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 852.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 838.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 838.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 832.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 831.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 831.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 821.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 821.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 812.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 808.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 801.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 799.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 789.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 786.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 773.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 769.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 764.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 756.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 755.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 753.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 752.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 746.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 737.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 733.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 732.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 726.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 722.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 718.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 717.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 714.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 713.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 707.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 692.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 688.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 685.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 678.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 673.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 668.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 666.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 646.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 645.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 638.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 622.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 618.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 606.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 596.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 586.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 585.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 577.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 576.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 573.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 573.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 563.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 557.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 557.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 556.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 550.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 549.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 541.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 534.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 533.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 529.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 525.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 520.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 516.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 503.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 503.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 502.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 499.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 495.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 494.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 489.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 488.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 488.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 488.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 482.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 479.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 475.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 460.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 436.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 423.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 422.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 421.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 419.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 418.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 418.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 417.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 358.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 322.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 321.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 301.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 279.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 275.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 252.6
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

3790.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 3790.5
FF:10158-103A5 76 years, female 3790.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

2005.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 1516.5
Samples: 4

Max nTPM: 2436.1
Min nTPM: 1010.3
Sample A Female 1349.6
Sample B Female 1010.3
Sample C Male 1269.8
Sample D Male 2436.1
Midbrain
nTPM: 2005.7
Samples: 4

Max nTPM: 5602.2
Min nTPM: 525.1
Sample A Female 5602.2
Sample B Female 1146.2
Sample C Male 749.3
Sample D Male 525.1
Periaqueductal gray
nTPM: 762.5
Samples: 3

Max nTPM: 940.1
Min nTPM: 537.4
Sample B Female 940.1
Sample C Male 537.4
Sample D Male 809.9
Superior colliculi
nTPM: 1171.8
Samples: 4

Max nTPM: 1490.2
Min nTPM: 560.2
Sample A Female 1238.8
Sample B Female 560.2
Sample C Male 1490.2
Sample D Male 1397.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

328.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 328.8
Samples: 4

Max nTPM: 345.1
Min nTPM: 311.8
Sample A Male 345.1
Sample B Male 331.5
Sample C Female 326.7
Sample D Female 311.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

15.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.2
71380893 Antisense, RP_050421_01_F01, Mouse strain C57BL/6J (56 days, male) 15.2

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