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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:877.7 nTPM
HPA Brain:275.9 nTPM
GTEx:877.7 nTPM
FANTOM5:8.7 Scaled Tags Per Million
Mouse:4.0 nTPM
Allen mouse:0.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

275.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 223.4
1870 Female, age 42, unknown 269.6
2666 Male, age 74, left hemisphere 248.8
2828 Female, age 72, unknown 242.2
1833 Male, age 53, unknown 231.7
1830 Male, age 51, unknown 231.1
2411 Female, age 72, unknown 221.5
2219 Male, age 76, both hemispheres 209.8
1827 Male, age 72, unknown 207.3
2019 Male, age 18, unknown 190.7
2586 Male, age 75, left hemisphere 181.4
Dorsal raphe nucleus
nTPM: 227.0
2016 Female, age 72, unknown 245.4
2298 Female, age 72, unknown 237.8
2750 Male, age 76, both hemispheres 230.4
1828 Male, age 53, unknown 213.3
2047 Male, age 72, unknown 208.0
Inferior colliculus
nTPM: 211.0
1890 Male, age 53, unknown 228.1
2849 Male, age 72, unknown 217.5
1848 Female, age 42, unknown 209.5
2097 Female, age 72, unknown 189.0
Median raphe nucleus
nTPM: 275.9
2220 Male, age 76, midline 275.9
Periaquaductal grey, anterior
nTPM: 217.1
2502 Female, age 75, unknown 227.5
1795 Male, age 51, unknown 216.2
1947 Male, age 18, unknown 207.6
Periaquaductal grey, dorsal
nTPM: 237.1
2850 Male, age 76, both hemispheres 275.0
1831 Male, age 72, unknown 244.8
1840 Male, age 53, unknown 225.2
2464 Female, age 72, unknown 203.3
Periaquaductal grey, lateral
nTPM: 241.0
2053 Male, age 18, unknown 250.3
2140 Male, age 76, both hemispheres 238.7
2272 Male, age 74, both hemispheres 233.8
Pretectal area
nTPM: 215.6
2224 Female, age 72, unknown 236.3
2316 Male, age 76, right hemisphere 230.7
1815 Male, age 53, unknown 229.7
1817 Female, age 42, unknown 229.6
2273 Male, age 74, both hemispheres 219.8
2825 Male, age 18, unknown 217.6
1944 Female, age 72, unknown 215.3
1816 Male, age 51, unknown 203.5
2007 Male, age 72, unknown 200.2
2407 Male, age 75, both hemispheres 198.8
2667 Female, age 75, unknown 190.3
Red nucleus
nTPM: 247.6
2503 Female, age 72, unknown 305.3
1865 Male, age 51, unknown 281.3
1904 Male, age 53, unknown 261.2
1821 Female, age 72, unknown 257.5
2725 Female, age 75, unknown 252.0
2769 Male, age 72, unknown 243.3
2785 Male, age 18, unknown 233.3
1954 Female, age 42, unknown 233.0
2584 Male, age 75, left hemisphere 231.8
2823 Male, age 76, right hemisphere 230.3
2227 Male, age 72, unknown 224.8
2588 Male, age 74, left hemisphere 217.7
Substantia nigra
nTPM: 264.0
2699 Male, age 18, unknown 346.3
1851 Male, age 51, unknown 299.1
2241 Male, age 72, unknown 278.8
2665 Male, age 74, both hemispheres 274.3
2409 Female, age 72, unknown 269.8
1916 Female, age 42, unknown 261.1
2590 Female, age 75, unknown 251.4
1889 Female, age 72, unknown 238.4
1941 Male, age 53, unknown 223.9
2583 Male, age 75, right hemisphere 197.3
Superior colliculus
nTPM: 233.7
2587 Male, age 74, left hemisphere 289.6
1913 Female, age 42, unknown 281.2
1995 Male, age 72, unknown 279.8
2668 Female, age 75, unknown 252.4
1796 Male, age 53, unknown 236.6
2261 Male, age 18, unknown 212.4
1839 Male, age 51, unknown 207.8
1895 Male, age 76, right hemisphere 204.4
2087 Female, age 72, unknown 200.1
2664 Male, age 75, both hemispheres 172.3
Ventral tegmental area
nTPM: 273.3
2223 Female, age 72, unknown 310.4
1915 Female, age 42, unknown 285.6
2218 Male, age 76, both hemispheres 271.7
2021 Male, age 53, unknown 268.9
2410 Female, age 72, unknown 267.9
1942 Male, age 51, unknown 235.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

877.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 877.7
Samples: 139

Max nTPM: 2969.6
Min nTPM: 261.6
Std nTPM: 373.6
Median nTPM: 792.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 2969.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2235.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1883.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1593.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1559.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1554.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1548.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1473.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1457.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1455.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1423.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1412.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1397.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1363.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1331.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1311.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1296.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1282.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1273.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1261.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1246.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1233.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1222.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1207.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1154.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1153.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1147.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1135.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1085.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1075.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1068.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1066.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1054.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1044.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1036.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1035.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1031.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1029.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1021.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1014.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1009.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1007.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1000.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 982.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 975.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 972.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 961.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 945.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 928.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 923.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 908.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 905.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 893.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 888.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 886.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 883.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 883.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 882.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 874.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 865.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 851.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 848.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 844.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 843.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 830.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 826.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 812.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 806.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 798.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 792.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 788.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 780.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 776.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 764.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 764.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 760.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 747.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 741.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 741.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 724.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 722.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 721.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 720.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 718.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 709.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 709.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 708.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 705.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 705.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 697.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 689.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 684.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 684.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 680.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 673.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 666.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 661.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 660.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 659.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 653.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 647.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 639.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 633.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 632.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 628.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 627.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 618.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 617.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 615.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 592.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 591.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 560.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 559.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 554.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 547.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 546.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 544.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 542.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 536.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 531.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 526.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 526.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 522.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 517.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 509.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 503.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 502.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 494.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 478.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 477.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 469.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 469.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 456.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 454.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 447.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 444.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 425.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 331.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 261.6
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

8.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 8.7
FF:10158-103A5 76 years, female 8.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

4.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 4.0
Samples: 4

Max nTPM: 5.6
Min nTPM: 2.9
Sample A Male 5.6
Sample B Male 2.9
Sample C Female 3.4
Sample D Female 3.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.0
70813317 Antisense, RP_050712_03_F09, Mouse strain C57BL/6J (56 days, male) 0.0

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