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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:102676.5 nTPM
HPA Brain:110698.4 nTPM
GTEx:102676.5 nTPM
Pig:95675.0 nTPM
Mouse:30965.9 nTPM
Allen mouse:24.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

110698.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 94668.4
2586 Male, age 75, left hemisphere 170728.9
2828 Female, age 72, unknown 123902.9
2666 Male, age 74, left hemisphere 109389.1
2219 Male, age 76, both hemispheres 106318.7
1833 Male, age 53, unknown 84757.0
2019 Male, age 18, unknown 81382.8
1870 Female, age 42, unknown 76935.9
1827 Male, age 72, unknown 75573.5
1830 Male, age 51, unknown 72726.2
2411 Female, age 72, unknown 44969.3
Dorsal raphe nucleus
nTPM: 68582.1
1828 Male, age 53, unknown 95516.2
2047 Male, age 72, unknown 73296.9
2750 Male, age 76, both hemispheres 68759.1
2016 Female, age 72, unknown 65085.3
2298 Female, age 72, unknown 40253.1
Inferior colliculus
nTPM: 74316.3
2849 Male, age 72, unknown 86769.0
1890 Male, age 53, unknown 85100.2
1848 Female, age 42, unknown 75408.3
2097 Female, age 72, unknown 49987.5
Median raphe nucleus
nTPM: 99562.5
2220 Male, age 76, midline 99562.5
Periaquaductal grey, anterior
nTPM: 68970.8
2502 Female, age 75, unknown 82830.4
1795 Male, age 51, unknown 65077.9
1947 Male, age 18, unknown 59004.1
Periaquaductal grey, dorsal
nTPM: 69861.9
2850 Male, age 76, both hemispheres 82571.8
1831 Male, age 72, unknown 70365.3
2464 Female, age 72, unknown 63745.3
1840 Male, age 53, unknown 62765.4
Periaquaductal grey, lateral
nTPM: 48951.4
2053 Male, age 18, unknown 57686.9
2140 Male, age 76, both hemispheres 51517.4
2272 Male, age 74, both hemispheres 37649.9
Pretectal area
nTPM: 87017.2
1817 Female, age 42, unknown 128864.4
1816 Male, age 51, unknown 127054.3
1944 Female, age 72, unknown 123725.0
2667 Female, age 75, unknown 115742.6
2007 Male, age 72, unknown 110940.1
1815 Male, age 53, unknown 103933.8
2825 Male, age 18, unknown 70894.0
2407 Male, age 75, both hemispheres 52512.3
2316 Male, age 76, right hemisphere 45691.0
2224 Female, age 72, unknown 44567.1
2273 Male, age 74, both hemispheres 33264.3
Red nucleus
nTPM: 87487.6
2584 Male, age 75, left hemisphere 118027.8
2588 Male, age 74, left hemisphere 114586.8
2503 Female, age 72, unknown 97662.5
2785 Male, age 18, unknown 90506.2
1954 Female, age 42, unknown 90062.8
2823 Male, age 76, right hemisphere 82284.2
1821 Female, age 72, unknown 81282.2
1865 Male, age 51, unknown 80435.7
2227 Male, age 72, unknown 79655.2
2769 Male, age 72, unknown 78670.5
1904 Male, age 53, unknown 74383.6
2725 Female, age 75, unknown 62293.6
Substantia nigra
nTPM: 110698.4
2665 Male, age 74, both hemispheres 241942.3
1916 Female, age 42, unknown 122701.1
2699 Male, age 18, unknown 118143.2
2583 Male, age 75, right hemisphere 104899.8
1889 Female, age 72, unknown 100750.5
1941 Male, age 53, unknown 95609.9
1851 Male, age 51, unknown 92853.3
2241 Male, age 72, unknown 90816.4
2590 Female, age 75, unknown 78247.6
2409 Female, age 72, unknown 61019.7
Superior colliculus
nTPM: 82412.2
2664 Male, age 75, both hemispheres 132614.6
2087 Female, age 72, unknown 111385.5
2668 Female, age 75, unknown 81858.4
2587 Male, age 74, left hemisphere 81459.1
2261 Male, age 18, unknown 78394.1
1839 Male, age 51, unknown 71974.9
1913 Female, age 42, unknown 71722.1
1995 Male, age 72, unknown 67341.8
1796 Male, age 53, unknown 66505.9
1895 Male, age 76, right hemisphere 60865.6
Ventral tegmental area
nTPM: 81719.4
2218 Male, age 76, both hemispheres 113303.9
1942 Male, age 51, unknown 84800.5
2223 Female, age 72, unknown 81799.4
1915 Female, age 42, unknown 80155.9
2410 Female, age 72, unknown 67282.9
2021 Male, age 53, unknown 62973.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

102676.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 102676.5
Samples: 139

Max nTPM: 459082.0
Min nTPM: 5976.8
Std nTPM: 89696.6
Median nTPM: 74002.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 459082.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 453033.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 440419.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 304329.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 300779.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 291540.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 282128.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 275471.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 272198.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 262457.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 252756.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 245960.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 234889.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 229236.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 228889.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 224858.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 215803.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 215559.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 214635.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 207560.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 202158.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 191183.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 177908.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 171427.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 169305.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 163705.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 161361.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 161131.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 155073.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 153485.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 152771.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 150509.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 145991.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 138792.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 133646.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 131699.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 130562.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 130117.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 129743.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 124863.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 122590.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 121861.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 121572.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 119829.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 119215.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 108282.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 107160.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 107037.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 106189.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 101299.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 100543.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 100326.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 99956.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 98877.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 93765.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 92762.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 92155.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 88992.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 88638.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 86387.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 85956.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 84266.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 84070.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 82826.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 81216.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 79181.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 77391.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 76911.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 74533.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 74002.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 71171.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 71133.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 70966.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 68746.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 66272.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 66043.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 64256.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 63762.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 62594.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 62011.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 61034.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 58831.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 58257.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 57383.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 56522.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 55885.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 52567.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 49646.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 48372.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 47379.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 46338.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 45879.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 45812.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 44158.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 42854.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 42762.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 41824.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 41736.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 41014.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 40399.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 39681.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 39678.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 38965.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 38937.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 36449.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 36343.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 35551.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 35236.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 35207.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 34959.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 34239.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 34079.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 33962.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 33742.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 32924.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 32836.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 32789.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 32603.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 31524.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 30480.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 27376.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 26396.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 24921.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 24399.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 24308.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 22791.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 22758.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 22266.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 20751.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 20376.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 20305.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 17836.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 17118.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 15204.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 14051.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 13044.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 12150.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 9357.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 5976.8
Show allShow less

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

95675.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 84206.9
Samples: 4

Max nTPM: 115352.0
Min nTPM: 52305.9
Sample A Female 115352.0
Sample B Female 76761.3
Sample C Male 92408.4
Sample D Male 52305.9
Midbrain
nTPM: 92763.4
Samples: 4

Max nTPM: 114937.5
Min nTPM: 64445.8
Sample A Female 64445.8
Sample B Female 114937.5
Sample C Male 109329.8
Sample D Male 82340.6
Periaqueductal gray
nTPM: 68683.4
Samples: 3

Max nTPM: 83546.0
Min nTPM: 52853.2
Sample B Female 83546.0
Sample C Male 69651.1
Sample D Male 52853.2
Superior colliculi
nTPM: 95675.1
Samples: 4

Max nTPM: 120238.2
Min nTPM: 63757.9
Sample A Female 104731.1
Sample B Female 63757.9
Sample C Male 120238.2
Sample D Male 93973.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

30965.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 30965.9
Samples: 4

Max nTPM: 32684.9
Min nTPM: 29288.7
Sample A Male 32684.9
Sample B Male 31418.4
Sample C Female 30471.7
Sample D Female 29288.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

24.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 24.0
73927706 Antisense, RP_051219_01_F08, Mouse strain C57BL/6J (56 days, male) 24.0
75043148 Antisense, RP_051219_01_F08, Mouse strain C57BL/6J (56 days, male) 22.6

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The Human Protein Atlas

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


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