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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:165.9 nTPM
HPA Brain:137.3 nTPM
GTEx:165.9 nTPM
FANTOM5:94.8 Scaled Tags Per Million
Pig:181.7 nTPM
Mouse:70.5 nTPM
Allen mouse:6.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

137.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 125.0
2666 Male, age 74, left hemisphere 135.5
2586 Male, age 75, left hemisphere 133.7
1870 Female, age 42, unknown 132.3
2411 Female, age 72, unknown 131.2
1827 Male, age 72, unknown 129.3
1830 Male, age 51, unknown 127.4
1833 Male, age 53, unknown 127.2
2019 Male, age 18, unknown 126.1
2828 Female, age 72, unknown 122.6
2219 Male, age 76, both hemispheres 84.6
Dorsal raphe nucleus
nTPM: 126.2
2298 Female, age 72, unknown 145.8
2047 Male, age 72, unknown 135.1
2750 Male, age 76, both hemispheres 128.7
1828 Male, age 53, unknown 114.1
2016 Female, age 72, unknown 107.3
Inferior colliculus
nTPM: 128.0
2849 Male, age 72, unknown 133.8
1848 Female, age 42, unknown 132.1
1890 Male, age 53, unknown 125.9
2097 Female, age 72, unknown 120.2
Median raphe nucleus
nTPM: 113.5
2220 Male, age 76, midline 113.5
Periaquaductal grey, anterior
nTPM: 122.1
1947 Male, age 18, unknown 129.1
2502 Female, age 75, unknown 128.9
1795 Male, age 51, unknown 108.3
Periaquaductal grey, dorsal
nTPM: 108.8
1840 Male, age 53, unknown 118.2
2850 Male, age 76, both hemispheres 110.7
2464 Female, age 72, unknown 107.1
1831 Male, age 72, unknown 99.0
Periaquaductal grey, lateral
nTPM: 106.4
2053 Male, age 18, unknown 108.0
2140 Male, age 76, both hemispheres 106.5
2272 Male, age 74, both hemispheres 104.9
Pretectal area
nTPM: 117.0
2007 Male, age 72, unknown 143.5
1817 Female, age 42, unknown 136.8
2667 Female, age 75, unknown 126.7
1815 Male, age 53, unknown 120.6
2825 Male, age 18, unknown 118.1
1816 Male, age 51, unknown 114.5
2224 Female, age 72, unknown 111.2
2407 Male, age 75, both hemispheres 109.0
1944 Female, age 72, unknown 104.1
2316 Male, age 76, right hemisphere 103.1
2273 Male, age 74, both hemispheres 99.8
Red nucleus
nTPM: 137.3
1821 Female, age 72, unknown 156.4
2769 Male, age 72, unknown 151.1
2785 Male, age 18, unknown 143.6
2227 Male, age 72, unknown 142.6
1904 Male, age 53, unknown 140.8
2588 Male, age 74, left hemisphere 139.1
1865 Male, age 51, unknown 137.6
2503 Female, age 72, unknown 134.7
1954 Female, age 42, unknown 130.7
2823 Male, age 76, right hemisphere 126.9
2584 Male, age 75, left hemisphere 123.1
2725 Female, age 75, unknown 120.8
Substantia nigra
nTPM: 107.4
1889 Female, age 72, unknown 130.1
1916 Female, age 42, unknown 124.1
2665 Male, age 74, both hemispheres 122.4
1851 Male, age 51, unknown 116.9
1941 Male, age 53, unknown 115.7
2583 Male, age 75, right hemisphere 114.6
2699 Male, age 18, unknown 100.9
2590 Female, age 75, unknown 96.0
2409 Female, age 72, unknown 81.4
2241 Male, age 72, unknown 72.3
Superior colliculus
nTPM: 120.6
2587 Male, age 74, left hemisphere 147.6
1839 Male, age 51, unknown 130.9
2668 Female, age 75, unknown 129.7
1895 Male, age 76, right hemisphere 123.2
2664 Male, age 75, both hemispheres 122.6
1796 Male, age 53, unknown 118.8
1995 Male, age 72, unknown 115.1
1913 Female, age 42, unknown 111.6
2261 Male, age 18, unknown 107.8
2087 Female, age 72, unknown 98.6
Ventral tegmental area
nTPM: 117.3
2223 Female, age 72, unknown 134.0
2410 Female, age 72, unknown 131.0
1915 Female, age 42, unknown 120.9
2218 Male, age 76, both hemispheres 109.9
1942 Male, age 51, unknown 107.0
2021 Male, age 53, unknown 100.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

165.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 165.9
Samples: 139

Max nTPM: 329.8
Min nTPM: 87.8
Std nTPM: 40.9
Median nTPM: 158.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 329.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 315.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 303.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 302.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 256.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 245.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 235.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 231.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 229.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 227.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 225.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 222.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 221.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 218.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 218.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 216.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 211.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 205.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 202.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 201.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 200.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 198.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 197.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 196.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 194.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 194.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 193.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 192.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 191.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 191.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 191.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 188.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 188.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 187.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 186.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 182.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 182.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 181.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 180.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 180.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 180.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 175.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 174.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 174.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 174.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 172.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 171.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 169.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 169.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 169.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 169.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 168.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 168.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 168.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 167.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 167.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 166.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 166.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 164.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 164.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 162.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 162.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 162.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 161.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 160.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 160.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 160.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 159.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 158.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 158.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 158.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 157.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 156.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 156.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 155.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 155.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 155.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 155.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 154.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 153.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 153.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 152.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 151.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 150.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 150.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 149.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 149.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 149.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 148.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 147.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 147.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 147.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 146.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 146.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 146.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 145.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 145.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 144.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 144.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 143.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 143.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 143.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 142.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 141.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 138.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 138.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 137.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 137.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 137.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 136.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 136.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 135.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 134.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 133.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 132.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 132.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 130.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 129.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 129.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 128.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 127.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 126.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 124.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 124.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 124.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 123.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 123.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 122.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 122.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 121.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 119.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 118.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 118.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 117.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 105.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 100.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 94.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 88.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 87.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

94.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 94.8
FF:10158-103A5 76 years, female 94.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

181.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 151.7
Samples: 4

Max nTPM: 190.7
Min nTPM: 123.8
Sample A Female 190.7
Sample B Female 123.8
Sample C Male 155.9
Sample D Male 136.2
Midbrain
nTPM: 179.7
Samples: 4

Max nTPM: 232.3
Min nTPM: 158.5
Sample A Female 232.3
Sample B Female 158.7
Sample C Male 158.5
Sample D Male 169.2
Periaqueductal gray
nTPM: 143.0
Samples: 3

Max nTPM: 149.3
Min nTPM: 138.9
Sample B Female 138.9
Sample C Male 149.3
Sample D Male 140.8
Superior colliculi
nTPM: 181.7
Samples: 4

Max nTPM: 223.3
Min nTPM: 136.9
Sample A Female 223.3
Sample B Female 136.9
Sample C Male 187.0
Sample D Male 179.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

70.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 70.5
Samples: 4

Max nTPM: 84.1
Min nTPM: 57.6
Sample A Male 84.1
Sample B Male 67.4
Sample C Female 57.6
Sample D Female 72.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

6.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.1
69837974 Antisense, RP_050224_01_D02, Mouse strain C57BL/6J (56 days, male) 7.4
74819344 Antisense, RP_060315_02_E11, Mouse strain C57BL/6J (56 days, male) 4.7

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