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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:1743.9 nTPM
HPA Brain:471.1 nTPM
GTEx:1743.9 nTPM
FANTOM5:102.0 Scaled Tags Per Million
Mouse:0.2 nTPM
Allen mouse:3.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

471.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 414.4
2666 Male, age 74, left hemisphere 509.0
2586 Male, age 75, left hemisphere 479.3
1870 Female, age 42, unknown 463.7
2828 Female, age 72, unknown 416.6
2411 Female, age 72, unknown 410.7
1827 Male, age 72, unknown 402.4
2019 Male, age 18, unknown 389.0
1833 Male, age 53, unknown 373.9
1830 Male, age 51, unknown 367.9
2219 Male, age 76, both hemispheres 331.2
Dorsal raphe nucleus
nTPM: 415.4
2298 Female, age 72, unknown 463.7
2750 Male, age 76, both hemispheres 450.0
2016 Female, age 72, unknown 438.7
1828 Male, age 53, unknown 385.1
2047 Male, age 72, unknown 339.7
Inferior colliculus
nTPM: 385.9
1890 Male, age 53, unknown 431.8
2097 Female, age 72, unknown 402.6
2849 Male, age 72, unknown 372.7
1848 Female, age 42, unknown 336.6
Median raphe nucleus
nTPM: 402.3
2220 Male, age 76, midline 402.3
Periaquaductal grey, anterior
nTPM: 428.9
2502 Female, age 75, unknown 524.9
1795 Male, age 51, unknown 390.3
1947 Male, age 18, unknown 371.4
Periaquaductal grey, dorsal
nTPM: 389.2
1840 Male, age 53, unknown 455.0
1831 Male, age 72, unknown 376.5
2464 Female, age 72, unknown 376.1
2850 Male, age 76, both hemispheres 349.4
Periaquaductal grey, lateral
nTPM: 362.9
2053 Male, age 18, unknown 410.2
2140 Male, age 76, both hemispheres 379.2
2272 Male, age 74, both hemispheres 299.4
Pretectal area
nTPM: 384.6
2316 Male, age 76, right hemisphere 455.3
2224 Female, age 72, unknown 417.7
1817 Female, age 42, unknown 413.2
2007 Male, age 72, unknown 409.3
2825 Male, age 18, unknown 400.8
1815 Male, age 53, unknown 399.2
1816 Male, age 51, unknown 369.4
1944 Female, age 72, unknown 355.8
2667 Female, age 75, unknown 353.4
2407 Male, age 75, both hemispheres 351.7
2273 Male, age 74, both hemispheres 304.3
Red nucleus
nTPM: 457.6
2503 Female, age 72, unknown 556.6
1865 Male, age 51, unknown 518.8
1904 Male, age 53, unknown 515.5
1821 Female, age 72, unknown 475.2
2227 Male, age 72, unknown 471.9
2584 Male, age 75, left hemisphere 469.7
2769 Male, age 72, unknown 438.4
2588 Male, age 74, left hemisphere 434.8
2785 Male, age 18, unknown 430.2
2725 Female, age 75, unknown 429.7
1954 Female, age 42, unknown 391.7
2823 Male, age 76, right hemisphere 358.5
Substantia nigra
nTPM: 471.1
1851 Male, age 51, unknown 593.8
2665 Male, age 74, both hemispheres 561.7
2699 Male, age 18, unknown 551.9
2241 Male, age 72, unknown 534.9
2409 Female, age 72, unknown 487.2
1916 Female, age 42, unknown 460.3
1889 Female, age 72, unknown 411.0
2590 Female, age 75, unknown 396.8
2583 Male, age 75, right hemisphere 366.9
1941 Male, age 53, unknown 346.0
Superior colliculus
nTPM: 430.9
1913 Female, age 42, unknown 522.8
2587 Male, age 74, left hemisphere 513.3
2668 Female, age 75, unknown 461.8
1995 Male, age 72, unknown 455.3
2664 Male, age 75, both hemispheres 414.9
1796 Male, age 53, unknown 414.4
2087 Female, age 72, unknown 391.8
2261 Male, age 18, unknown 383.2
1839 Male, age 51, unknown 376.8
1895 Male, age 76, right hemisphere 375.2
Ventral tegmental area
nTPM: 453.1
1915 Female, age 42, unknown 528.7
2223 Female, age 72, unknown 511.7
2021 Male, age 53, unknown 468.7
1942 Male, age 51, unknown 438.2
2410 Female, age 72, unknown 408.2
2218 Male, age 76, both hemispheres 363.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1743.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1743.9
Samples: 139

Max nTPM: 4509.1
Min nTPM: 592.7
Std nTPM: 719.1
Median nTPM: 1591.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 4509.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 4291.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 4243.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 3993.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 3896.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 3554.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 3181.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 3094.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 2821.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 2816.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 2769.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 2672.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 2622.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 2622.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 2599.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 2598.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 2527.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 2483.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 2397.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 2325.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 2314.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 2292.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 2291.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 2225.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 2225.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 2209.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 2197.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 2147.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 2140.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 2114.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 2102.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 2051.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 2049.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 2040.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 2034.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 2017.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 2017.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 2016.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1997.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1986.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1980.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1959.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1946.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1917.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1904.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1898.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1879.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1878.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1853.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1840.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1824.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1807.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1790.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1773.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1764.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1757.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1757.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1748.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1741.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1698.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1684.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1673.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1655.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1655.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1654.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1643.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1617.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1604.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1604.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1591.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1586.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1569.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1559.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1557.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1539.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1537.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1531.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1522.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1511.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1497.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1484.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1464.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1444.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1435.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1421.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1420.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1412.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1405.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1396.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1378.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 1376.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1363.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1337.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1332.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1331.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1323.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1323.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 1322.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1317.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1314.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 1313.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1300.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1291.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1289.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1277.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1264.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1264.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1231.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1229.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1203.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 1193.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 1184.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 1180.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1179.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 1177.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1169.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 1163.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1130.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1109.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1109.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1095.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 1059.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 1048.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 1040.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 1037.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 1032.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 1005.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 991.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 983.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 939.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 918.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 907.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 867.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 829.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 818.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 806.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 795.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 755.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 592.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

102.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 102.0
FF:10158-103A5 76 years, female 102.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 0.3
Samples: 4

Max nTPM: 0.6
Min nTPM: 0.0
Sample A Male 0.6
Sample B Male 0.2
Sample C Female 0.2
Sample D Female 0.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.1
69873283 Antisense, RP_050510_04_H10, Mouse strain C57BL/6J (56 days, male) 3.1

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