News ArticlesHuman Protein Atlas study on primary cilia published in CellIn the journal Cell, researchers publish a deep analysis of the HPA primary cilia section, first introduced in HPA v24. The HPA subcellular resource portrays primary cilia as the most heterogeneous organelles, customized by the cell for fine-tuned environmental sensing, and inspires many new views on this tiny antenna...Read more Transcription factors SP5 and SP8 regulate primary cilia formation during embryogenesisPrimary cilia are thin projections that are present on most cell types and that serve critical functions during multiple biological processes, including embryonic development. They are present in a single copy per cell and act much like an antenna, receiving and sending signals to the environment. This makes them crucial for coordinating cellular processes early in life...Read more CFAP300 - A new standard marker for cilia?With the recent release of version 24 of the Human Protein Atlas we provide a detailed map of 654 proteins that localize to a small, but important organelle, called the primary cilium. This tiny protrusion is present on most human cell types and serves as a cellular antenna, providing a compartment that is optimal for carefully sensing, transducing and relaying information from the extracellular environment...Read more |