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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:93.7 nTPM
HPA Brain:419.7 nTPM
GTEx:93.7 nTPM
FANTOM5:46.4 Scaled Tags Per Million
Pig:439.4 nTPM
Mouse:438.2 nTPM
Allen mouse:15.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

419.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 209.5
1827 Male, age 72, unknown 277.9
2219 Male, age 76, both hemispheres 268.7
2666 Male, age 74, left hemisphere 242.2
1870 Female, age 42, unknown 220.6
2411 Female, age 72, unknown 201.8
2828 Female, age 72, unknown 195.8
1833 Male, age 53, unknown 191.3
2586 Male, age 75, left hemisphere 167.0
2019 Male, age 18, unknown 166.0
1830 Male, age 51, unknown 163.5
Dorsal raphe nucleus
nTPM: 266.4
2298 Female, age 72, unknown 339.9
2047 Male, age 72, unknown 282.3
1828 Male, age 53, unknown 265.1
2750 Male, age 76, both hemispheres 250.9
2016 Female, age 72, unknown 193.8
Inferior colliculus
nTPM: 277.3
2097 Female, age 72, unknown 329.2
2849 Male, age 72, unknown 284.1
1848 Female, age 42, unknown 275.8
1890 Male, age 53, unknown 219.9
Median raphe nucleus
nTPM: 419.7
2220 Male, age 76, midline 419.7
Periaquaductal grey, anterior
nTPM: 267.8
2502 Female, age 75, unknown 310.1
1795 Male, age 51, unknown 260.9
1947 Male, age 18, unknown 232.5
Periaquaductal grey, dorsal
nTPM: 246.4
1840 Male, age 53, unknown 318.0
2850 Male, age 76, both hemispheres 248.0
2464 Female, age 72, unknown 211.3
1831 Male, age 72, unknown 208.4
Periaquaductal grey, lateral
nTPM: 211.0
2053 Male, age 18, unknown 224.5
2140 Male, age 76, both hemispheres 221.5
2272 Male, age 74, both hemispheres 186.9
Pretectal area
nTPM: 253.2
1816 Male, age 51, unknown 341.9
2224 Female, age 72, unknown 333.6
1944 Female, age 72, unknown 317.5
1817 Female, age 42, unknown 274.2
2007 Male, age 72, unknown 257.1
2825 Male, age 18, unknown 254.1
1815 Male, age 53, unknown 241.7
2667 Female, age 75, unknown 220.6
2316 Male, age 76, right hemisphere 188.3
2407 Male, age 75, both hemispheres 183.4
2273 Male, age 74, both hemispheres 173.2
Red nucleus
nTPM: 133.4
2584 Male, age 75, left hemisphere 180.0
1821 Female, age 72, unknown 160.4
2785 Male, age 18, unknown 159.1
2227 Male, age 72, unknown 139.1
2725 Female, age 75, unknown 138.3
2769 Male, age 72, unknown 135.2
2503 Female, age 72, unknown 127.1
1954 Female, age 42, unknown 121.5
2823 Male, age 76, right hemisphere 116.9
2588 Male, age 74, left hemisphere 112.6
1865 Male, age 51, unknown 109.1
1904 Male, age 53, unknown 101.6
Substantia nigra
nTPM: 262.9
1916 Female, age 42, unknown 365.2
1941 Male, age 53, unknown 317.7
2241 Male, age 72, unknown 311.0
2665 Male, age 74, both hemispheres 292.0
1889 Female, age 72, unknown 279.5
1851 Male, age 51, unknown 271.0
2409 Female, age 72, unknown 260.0
2699 Male, age 18, unknown 237.7
2590 Female, age 75, unknown 149.4
2583 Male, age 75, right hemisphere 145.1
Superior colliculus
nTPM: 228.8
2668 Female, age 75, unknown 339.6
1895 Male, age 76, right hemisphere 279.6
2087 Female, age 72, unknown 266.5
1796 Male, age 53, unknown 257.9
2261 Male, age 18, unknown 250.0
1839 Male, age 51, unknown 235.3
2664 Male, age 75, both hemispheres 207.0
2587 Male, age 74, left hemisphere 172.8
1913 Female, age 42, unknown 157.3
1995 Male, age 72, unknown 122.2
Ventral tegmental area
nTPM: 260.8
2218 Male, age 76, both hemispheres 317.2
1915 Female, age 42, unknown 286.4
1942 Male, age 51, unknown 252.2
2410 Female, age 72, unknown 237.6
2223 Female, age 72, unknown 236.0
2021 Male, age 53, unknown 235.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

93.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 93.7
Samples: 139

Max nTPM: 350.5
Min nTPM: 9.2
Std nTPM: 72.5
Median nTPM: 67.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 350.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 324.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 274.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 264.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 261.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 261.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 253.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 237.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 235.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 234.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 226.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 204.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 204.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 199.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 199.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 198.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 196.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 192.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 181.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 173.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 168.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 167.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 163.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 161.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 158.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 155.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 154.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 154.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 150.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 146.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 145.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 145.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 143.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 140.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 134.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 132.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 129.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 126.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 123.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 121.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 121.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 112.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 111.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 110.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 109.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 109.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 109.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 109.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 107.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 104.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 101.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 100.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 100.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 100.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 99.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 98.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 97.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 91.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 88.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 87.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 85.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 82.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 81.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 77.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 76.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 74.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 71.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 71.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 69.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 67.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 65.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 63.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 63.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 62.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 62.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 61.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 60.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 59.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 58.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 57.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 54.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 54.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 53.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 52.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 52.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 50.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 50.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 49.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 48.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 48.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 48.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 47.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 47.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 46.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 46.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 43.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 42.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 41.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 39.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 39.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 38.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 37.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 37.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 37.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 37.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 36.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 36.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 35.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 35.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 34.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 34.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 34.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 33.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 32.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 31.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 30.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 29.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 28.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 27.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 27.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 24.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 24.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 23.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 23.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 22.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 22.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 21.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 21.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 19.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 19.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 19.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 19.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 15.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 15.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 14.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 12.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 10.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 9.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 9.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

46.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 46.4
FF:10158-103A5 76 years, female 46.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

439.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 281.8
Samples: 4

Max nTPM: 422.6
Min nTPM: 122.7
Sample A Female 360.1
Sample B Female 221.9
Sample C Male 422.6
Sample D Male 122.7
Midbrain
nTPM: 439.3
Samples: 4

Max nTPM: 615.7
Min nTPM: 102.4
Sample A Female 102.4
Sample B Female 459.7
Sample C Male 579.5
Sample D Male 615.7
Periaqueductal gray
nTPM: 394.2
Samples: 3

Max nTPM: 448.4
Min nTPM: 309.3
Sample B Female 448.4
Sample C Male 424.9
Sample D Male 309.3
Superior colliculi
nTPM: 377.4
Samples: 4

Max nTPM: 499.6
Min nTPM: 200.4
Sample A Female 410.0
Sample B Female 200.4
Sample C Male 399.7
Sample D Male 499.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

438.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 438.2
Samples: 4

Max nTPM: 459.4
Min nTPM: 385.8
Sample A Male 385.8
Sample B Male 458.8
Sample C Female 448.8
Sample D Female 459.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

15.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.9
74272037 Antisense, RP_060202_01_A04, Mouse strain C57BL/6J (56 days, male) 17.2
69549641 Antisense, RP_050309_02_D02, Mouse strain C57BL/6J (56 days, male) 14.7

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