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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:807.0 nTPM
HPA Brain:860.0 nTPM
GTEx:807.0 nTPM
FANTOM5:217.3 Scaled Tags Per Million
Pig:1540.4 nTPM
Mouse:1315.3 nTPM
Allen mouse:10.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

860.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 710.9
2019 Male, age 18, unknown 875.3
2586 Male, age 75, left hemisphere 855.2
1827 Male, age 72, unknown 823.7
2411 Female, age 72, unknown 802.2
2828 Female, age 72, unknown 735.3
2219 Male, age 76, both hemispheres 672.8
1833 Male, age 53, unknown 647.8
1870 Female, age 42, unknown 612.2
1830 Male, age 51, unknown 587.9
2666 Male, age 74, left hemisphere 496.1
Dorsal raphe nucleus
nTPM: 824.3
2298 Female, age 72, unknown 948.0
2047 Male, age 72, unknown 920.2
1828 Male, age 53, unknown 830.6
2750 Male, age 76, both hemispheres 727.9
2016 Female, age 72, unknown 695.0
Inferior colliculus
nTPM: 860.0
2097 Female, age 72, unknown 965.1
1848 Female, age 42, unknown 909.9
2849 Male, age 72, unknown 814.1
1890 Male, age 53, unknown 751.0
Median raphe nucleus
nTPM: 740.0
2220 Male, age 76, midline 740.0
Periaquaductal grey, anterior
nTPM: 627.9
2502 Female, age 75, unknown 663.4
1795 Male, age 51, unknown 636.5
1947 Male, age 18, unknown 583.9
Periaquaductal grey, dorsal
nTPM: 674.9
2464 Female, age 72, unknown 847.9
1840 Male, age 53, unknown 705.9
2850 Male, age 76, both hemispheres 621.8
1831 Male, age 72, unknown 524.0
Periaquaductal grey, lateral
nTPM: 568.0
2140 Male, age 76, both hemispheres 628.6
2053 Male, age 18, unknown 583.9
2272 Male, age 74, both hemispheres 491.4
Pretectal area
nTPM: 795.9
2007 Male, age 72, unknown 1149.1
1817 Female, age 42, unknown 1106.8
1944 Female, age 72, unknown 998.5
1816 Male, age 51, unknown 938.0
2667 Female, age 75, unknown 835.7
1815 Male, age 53, unknown 767.1
2224 Female, age 72, unknown 738.0
2825 Male, age 18, unknown 651.2
2316 Male, age 76, right hemisphere 614.2
2273 Male, age 74, both hemispheres 550.5
2407 Male, age 75, both hemispheres 406.2
Red nucleus
nTPM: 731.4
1821 Female, age 72, unknown 945.7
1954 Female, age 42, unknown 816.1
2588 Male, age 74, left hemisphere 805.1
2503 Female, age 72, unknown 795.6
2785 Male, age 18, unknown 789.9
2823 Male, age 76, right hemisphere 750.0
2227 Male, age 72, unknown 735.8
2769 Male, age 72, unknown 729.8
2725 Female, age 75, unknown 707.3
1865 Male, age 51, unknown 681.5
1904 Male, age 53, unknown 582.7
2584 Male, age 75, left hemisphere 437.7
Substantia nigra
nTPM: 718.4
1941 Male, age 53, unknown 1129.3
1889 Female, age 72, unknown 952.2
2665 Male, age 74, both hemispheres 844.8
1916 Female, age 42, unknown 735.4
1851 Male, age 51, unknown 640.2
2241 Male, age 72, unknown 631.5
2590 Female, age 75, unknown 607.2
2583 Male, age 75, right hemisphere 563.4
2699 Male, age 18, unknown 557.8
2409 Female, age 72, unknown 522.2
Superior colliculus
nTPM: 654.0
2087 Female, age 72, unknown 870.1
1895 Male, age 76, right hemisphere 792.5
1839 Male, age 51, unknown 723.8
2261 Male, age 18, unknown 711.2
1796 Male, age 53, unknown 686.1
2668 Female, age 75, unknown 646.4
2587 Male, age 74, left hemisphere 590.6
2664 Male, age 75, both hemispheres 568.3
1913 Female, age 42, unknown 494.7
1995 Male, age 72, unknown 456.8
Ventral tegmental area
nTPM: 643.8
2410 Female, age 72, unknown 777.8
2218 Male, age 76, both hemispheres 694.0
1915 Female, age 42, unknown 646.6
1942 Male, age 51, unknown 621.0
2223 Female, age 72, unknown 606.6
2021 Male, age 53, unknown 517.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

807.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 807.0
Samples: 139

Max nTPM: 2158.3
Min nTPM: 191.6
Std nTPM: 332.5
Median nTPM: 749.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 2158.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1666.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1665.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1617.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1603.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1582.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1501.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 1431.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1431.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1345.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1302.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1293.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1281.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1255.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1198.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1186.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1181.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1178.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1154.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1141.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1131.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1131.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1121.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 1110.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1109.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1105.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1082.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1081.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1079.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1072.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 1031.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 996.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 987.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 985.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 957.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 957.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 950.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 935.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 920.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 908.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 882.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 877.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 876.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 871.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 870.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 865.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 860.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 859.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 858.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 854.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 852.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 842.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 841.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 836.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 829.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 821.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 821.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 820.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 810.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 809.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 799.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 797.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 793.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 779.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 771.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 761.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 758.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 752.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 751.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 749.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 747.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 738.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 738.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 736.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 732.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 729.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 728.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 721.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 714.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 710.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 706.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 701.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 698.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 694.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 688.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 688.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 682.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 679.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 678.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 677.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 677.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 672.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 661.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 653.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 649.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 646.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 640.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 633.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 627.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 623.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 609.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 602.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 599.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 599.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 596.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 594.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 593.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 588.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 571.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 569.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 565.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 558.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 547.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 547.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 543.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 536.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 528.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 518.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 494.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 494.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 472.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 471.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 451.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 450.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 436.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 431.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 425.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 396.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 384.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 363.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 319.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 306.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 300.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 295.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 266.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 263.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 251.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 241.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 191.6
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

217.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 217.3
FF:10158-103A5 76 years, female 217.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1540.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 1323.5
Samples: 4

Max nTPM: 1588.5
Min nTPM: 1023.2
Sample A Female 1588.5
Sample B Female 1023.2
Sample C Male 1526.4
Sample D Male 1155.8
Midbrain
nTPM: 1540.4
Samples: 4

Max nTPM: 1902.6
Min nTPM: 1238.3
Sample A Female 1902.6
Sample B Female 1238.3
Sample C Male 1669.8
Sample D Male 1350.8
Periaqueductal gray
nTPM: 1304.7
Samples: 3

Max nTPM: 1523.5
Min nTPM: 1150.6
Sample B Female 1240.1
Sample C Male 1523.5
Sample D Male 1150.6
Superior colliculi
nTPM: 1383.6
Samples: 4

Max nTPM: 1746.7
Min nTPM: 710.4
Sample A Female 1528.3
Sample B Female 710.4
Sample C Male 1746.7
Sample D Male 1549.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1315.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 1315.3
Samples: 4

Max nTPM: 1439.5
Min nTPM: 1226.2
Sample A Male 1439.5
Sample B Male 1245.8
Sample C Female 1226.2
Sample D Female 1349.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

10.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.5
79556636 Antisense, RP_071204_01_A02, Mouse strain C57BL/6J (56 days, male) 13.9
275696 Antisense, RP_040617_01_C08, Mouse strain C57BL/6J (56 days, male) 13.0
73512352 Antisense, RP_050719_02_A05, Mouse strain C57BL/6J (56 days, male) 4.5
71022960 Antisense, RP_050719_02_A05, Mouse strain C57BL/6J (56 days, male) 3.9

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