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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:326.7 nTPM
HPA Brain:363.9 nTPM
GTEx:326.7 nTPM
FANTOM5:724.3 Scaled Tags Per Million
Pig:356.0 nTPM
Mouse:739.0 nTPM
Allen mouse:24.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

363.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 305.1
2411 Female, age 72, unknown 367.8
1827 Male, age 72, unknown 354.6
1870 Female, age 42, unknown 354.2
2019 Male, age 18, unknown 306.7
2666 Male, age 74, left hemisphere 293.1
1833 Male, age 53, unknown 292.9
2828 Female, age 72, unknown 291.2
1830 Male, age 51, unknown 282.2
2586 Male, age 75, left hemisphere 257.9
2219 Male, age 76, both hemispheres 250.4
Dorsal raphe nucleus
nTPM: 318.0
2298 Female, age 72, unknown 371.5
2750 Male, age 76, both hemispheres 327.0
2047 Male, age 72, unknown 305.3
1828 Male, age 53, unknown 302.4
2016 Female, age 72, unknown 283.9
Inferior colliculus
nTPM: 306.0
2097 Female, age 72, unknown 364.7
1848 Female, age 42, unknown 307.1
1890 Male, age 53, unknown 282.1
2849 Male, age 72, unknown 269.9
Median raphe nucleus
nTPM: 333.5
2220 Male, age 76, midline 333.5
Periaquaductal grey, anterior
nTPM: 340.8
1947 Male, age 18, unknown 373.8
2502 Female, age 75, unknown 351.0
1795 Male, age 51, unknown 297.7
Periaquaductal grey, dorsal
nTPM: 284.2
1840 Male, age 53, unknown 296.5
2464 Female, age 72, unknown 289.4
1831 Male, age 72, unknown 288.9
2850 Male, age 76, both hemispheres 262.2
Periaquaductal grey, lateral
nTPM: 265.7
2053 Male, age 18, unknown 299.9
2272 Male, age 74, both hemispheres 261.8
2140 Male, age 76, both hemispheres 235.3
Pretectal area
nTPM: 336.3
1816 Male, age 51, unknown 403.3
2007 Male, age 72, unknown 384.8
1815 Male, age 53, unknown 364.9
1944 Female, age 72, unknown 362.7
1817 Female, age 42, unknown 360.7
2224 Female, age 72, unknown 332.0
2667 Female, age 75, unknown 325.7
2273 Male, age 74, both hemispheres 316.2
2825 Male, age 18, unknown 298.7
2407 Male, age 75, both hemispheres 289.5
2316 Male, age 76, right hemisphere 261.3
Red nucleus
nTPM: 309.7
1821 Female, age 72, unknown 407.6
2503 Female, age 72, unknown 338.2
1954 Female, age 42, unknown 321.6
1865 Male, age 51, unknown 317.2
1904 Male, age 53, unknown 312.1
2725 Female, age 75, unknown 298.7
2785 Male, age 18, unknown 292.7
2227 Male, age 72, unknown 291.0
2769 Male, age 72, unknown 290.1
2588 Male, age 74, left hemisphere 283.1
2584 Male, age 75, left hemisphere 282.8
2823 Male, age 76, right hemisphere 280.9
Substantia nigra
nTPM: 363.9
2241 Male, age 72, unknown 419.2
1941 Male, age 53, unknown 412.2
1889 Female, age 72, unknown 390.9
1916 Female, age 42, unknown 387.1
1851 Male, age 51, unknown 383.7
2409 Female, age 72, unknown 379.5
2665 Male, age 74, both hemispheres 341.1
2590 Female, age 75, unknown 323.2
2583 Male, age 75, right hemisphere 308.0
2699 Male, age 18, unknown 294.3
Superior colliculus
nTPM: 313.8
2668 Female, age 75, unknown 356.4
2261 Male, age 18, unknown 355.8
2587 Male, age 74, left hemisphere 346.3
2087 Female, age 72, unknown 344.4
1796 Male, age 53, unknown 312.0
1913 Female, age 42, unknown 305.5
1839 Male, age 51, unknown 293.9
1895 Male, age 76, right hemisphere 288.7
2664 Male, age 75, both hemispheres 278.5
1995 Male, age 72, unknown 256.8
Ventral tegmental area
nTPM: 340.8
2410 Female, age 72, unknown 382.7
2223 Female, age 72, unknown 360.8
1915 Female, age 42, unknown 343.6
1942 Male, age 51, unknown 333.8
2218 Male, age 76, both hemispheres 323.6
2021 Male, age 53, unknown 300.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

326.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 326.7
Samples: 139

Max nTPM: 653.4
Min nTPM: 173.7
Std nTPM: 87.0
Median nTPM: 304.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 653.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 651.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 601.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 567.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 496.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 494.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 480.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 473.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 457.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 455.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 446.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 446.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 437.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 436.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 433.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 427.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 424.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 419.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 417.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 416.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 412.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 412.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 412.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 411.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 411.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 410.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 409.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 403.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 399.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 395.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 385.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 383.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 382.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 380.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 380.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 373.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 372.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 371.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 368.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 359.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 357.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 356.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 353.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 353.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 352.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 351.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 349.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 349.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 340.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 336.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 332.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 332.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 330.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 328.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 327.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 326.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 326.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 323.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 323.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 320.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 317.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 315.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 314.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 312.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 312.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 309.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 307.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 307.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 305.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 304.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 304.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 304.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 303.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 303.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 302.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 301.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 300.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 297.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 293.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 293.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 292.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 292.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 291.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 291.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 290.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 290.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 288.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 288.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 287.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 287.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 285.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 284.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 284.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 282.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 281.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 280.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 279.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 278.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 278.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 274.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 266.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 266.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 266.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 266.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 265.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 263.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 263.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 263.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 263.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 262.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 262.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 260.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 257.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 255.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 255.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 254.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 253.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 249.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 246.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 244.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 242.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 239.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 237.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 236.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 234.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 231.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 229.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 228.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 228.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 221.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 221.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 218.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 216.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 216.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 208.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 200.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 189.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 177.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 173.7
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

724.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 724.3
FF:10158-103A5 76 years, female 724.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

356.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 340.4
Samples: 4

Max nTPM: 449.4
Min nTPM: 252.1
Sample A Female 449.4
Sample B Female 317.5
Sample C Male 342.4
Sample D Male 252.1
Midbrain
nTPM: 356.0
Samples: 4

Max nTPM: 414.8
Min nTPM: 284.0
Sample A Female 414.8
Sample B Female 363.7
Sample C Male 361.3
Sample D Male 284.0
Periaqueductal gray
nTPM: 264.6
Samples: 3

Max nTPM: 278.8
Min nTPM: 239.0
Sample B Female 278.8
Sample C Male 275.9
Sample D Male 239.0
Superior colliculi
nTPM: 338.5
Samples: 4

Max nTPM: 392.4
Min nTPM: 296.9
Sample A Female 362.4
Sample B Female 302.1
Sample C Male 392.4
Sample D Male 296.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

739.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 739.0
Samples: 4

Max nTPM: 775.6
Min nTPM: 695.5
Sample A Male 695.5
Sample B Male 752.6
Sample C Female 775.6
Sample D Female 732.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

24.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 24.4
67752306 Antisense, RP_040922_01_D04, Mouse strain C57BL/6J (56 days, male) 26.2
77620375 Antisense, RP_070205_01_D08, Mouse strain C57BL/6J (56 days, male) 22.6
77413696 Antisense, RP_070205_01_D08, Mouse strain C57BL/6J (56 days, male) 21.9
68196968 Antisense, RP_040922_01_D04, Mouse strain C57BL/6J (56 days, male) 20.9

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