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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
153.5
nTPM
HPA:
153.5
nTPM
GTEx:
76.2
nTPM
FANTOM5:
501.3
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA002989
Antibody HPA003020
Antibody CAB002306
Cholangiocytes
Not detected
Not detected
Not detected
Hepatocytes
Not detected
Not detected
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
153.5
Female, age 60
Liver sample 21 nTPM: 218.8
Male, age 54
Liver sample 23 nTPM: 236.9
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 186
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 136.4
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 146.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 124.4
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 134.2
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 105.1
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 102.7
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 144.2
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
76.2
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 76.2
Samples: 226
Max nTPM: 381.7
Min nTPM: 11.7
Std nTPM: 51.4
Median nTPM: 66.2
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
381.7
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
343.1
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
337.1
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
312.1
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
207.9
GTEX-Q734-0326-SM-48U15
40-49 years, female
200.9
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
172.0
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
170.0
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
164.8
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
157.6
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
154.0
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
149.5
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
142.9
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
142.8
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
141.7
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
139.1
GTEX-S32W-1926-SM-4AD63
50-59 years, female
138.8
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
136.3
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
135.5
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
133.5
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
132.9
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
132.4
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
130.5
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
130.3
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
125.0
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
124.4
GTEX-11GSP-0626-SM-5986T
60-69 years, female
120.8
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
119.5
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
118.4
GTEX-QEL4-1226-SM-447A4
50-59 years, male
117.6
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
116.1
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
114.0
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
113.8
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
113.5
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
113.0
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
113.0
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
109.1
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
108.8
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
108.6
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
108.2
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
107.1
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
106.8
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
106.8
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
106.8
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
103.8
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
101.7
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
101.6
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
100.5
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
100.1
GTEX-X261-1726-SM-4PQYT
50-59 years, male
100.1
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
100.0
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
97.9
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
97.8
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
97.6
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
96.7
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
96.4
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
95.9
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
95.5
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
95.5
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
95.4
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
95.3
GTEX-12696-0826-SM-5EGGE
60-69 years, male
95.0
GTEX-14XAO-0226-SM-68728
60-69 years, female
94.6
GTEX-14JG1-1626-SM-664NH
40-49 years, male
93.5
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
92.5
GTEX-14E7W-1526-SM-6871X
70-79 years, male
92.4
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
89.5
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
88.5
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
86.0
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
86.0
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
85.8
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
85.1
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
85.0
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
84.8
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
83.0
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
82.0
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
82.0
GTEX-14PHX-0526-SM-664NW
50-59 years, male
81.3
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
81.2
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
81.1
GTEX-18A7A-1526-SM-72D69
50-59 years, female
81.1
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
80.3
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
80.2
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
80.2
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
79.9
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
79.9
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
78.2
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
77.7
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
77.3
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
77.2
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
77.1
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
75.0
GTEX-1B932-1426-SM-793AN
40-49 years, female
74.1
GTEX-1399T-0826-SM-5IFES
60-69 years, male
73.4
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
73.1
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
72.9
GTEX-1B933-1226-SM-731DW
50-59 years, female
72.5
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
72.0
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
71.6
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
71.4
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
71.1
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
70.9
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
70.1
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
69.7
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
69.7
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
68.5
GTEX-18A66-2026-SM-7189C
60-69 years, male
68.4
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
68.4
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
67.8
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
67.8
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
67.5
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
67.1
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
66.3
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
66.0
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
65.4
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
65.2
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
65.2
GTEX-13112-1426-SM-5EGH8
50-59 years, male
64.0
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
63.0
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
63.0
GTEX-17HHE-0126-SM-79398
50-59 years, male
62.8
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
62.4
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
62.2
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
61.1
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
60.7
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
60.5
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
59.9
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
59.9
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
59.6
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
59.3
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
59.2
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
59.1
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
58.8
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
58.7
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
58.6
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
57.9
GTEX-144GL-1426-SM-79OMA
50-59 years, male
57.1
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
56.7
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
56.2
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
55.5
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
55.4
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
55.0
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
53.0
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
53.0
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
52.9
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
52.0
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
51.9
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
51.5
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
51.4
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
51.3
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
51.3
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
51.0
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
50.7
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
50.1
GTEX-P78B-1326-SM-3P611
40-49 years, female
50.0
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
49.8
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
49.2
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
48.5
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
48.4
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
48.3
GTEX-14PJO-1726-SM-68719
60-69 years, male
48.3
GTEX-S33H-1626-SM-4AD68
30-39 years, male
47.9
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
47.0
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
47.0
GTEX-RN64-1826-SM-48FDV
50-59 years, male
46.6
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
45.5
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
45.0
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
44.5
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
44.4
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
42.8
GTEX-QESD-2026-SM-447BI
20-29 years, male
42.7
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
42.5
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
42.3
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
41.6
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
41.6
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
41.3
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
40.8
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
40.5
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
40.4
GTEX-YECK-1926-SM-4W21H
60-69 years, male
40.2
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
40.1
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
39.1
GTEX-RU72-1426-SM-46MUF
50-59 years, female
38.5
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
37.5
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
37.5
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
37.3
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
36.4
GTEX-11ZUS-2526-SM-59872
30-39 years, male
36.2
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
36.0
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
35.7
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
35.6
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
35.3
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
34.8
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
34.7
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
33.1
GTEX-R53T-0326-SM-48FEC
50-59 years, female
33.1
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
32.7
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
32.0
GTEX-13113-1326-SM-5GCOI
60-69 years, female
30.6
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
29.4
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
29.2
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
29.2
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
29.2
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
28.6
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
28.5
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
27.7
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
27.5
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
27.0
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
26.0
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
24.7
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
24.1
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
23.7
GTEX-17F96-1226-SM-79OK2
70-79 years, male
22.7
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
22.5
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
21.9
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
20.4
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
19.8
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
19.5
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
19.2
GTEX-O5YV-0726-SM-EV798
60-69 years, female
18.8
GTEX-REY6-1226-SM-48FDR
60-69 years, male
17.9
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
17.5
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
17.4
GTEX-18465-1626-SM-7LG6N
50-59 years, male
17.0
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
14.7
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
11.7
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
