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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:1014.1 nTPM
HPA Brain:1219.9 nTPM
GTEx:1014.1 nTPM
FANTOM5:1433.4 Scaled Tags Per Million
Pig:723.7 nTPM
Mouse:1349.7 nTPM
Allen mouse:24.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1219.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 823.2
2666 Male, age 74, left hemisphere 1052.6
1827 Male, age 72, unknown 1043.8
2586 Male, age 75, left hemisphere 894.7
2411 Female, age 72, unknown 882.6
2828 Female, age 72, unknown 842.7
2219 Male, age 76, both hemispheres 809.0
1870 Female, age 42, unknown 803.2
2019 Male, age 18, unknown 706.7
1833 Male, age 53, unknown 602.5
1830 Male, age 51, unknown 594.0
Dorsal raphe nucleus
nTPM: 846.4
2298 Female, age 72, unknown 1005.3
2750 Male, age 76, both hemispheres 993.3
2047 Male, age 72, unknown 895.2
1828 Male, age 53, unknown 825.1
2016 Female, age 72, unknown 512.9
Inferior colliculus
nTPM: 583.0
2097 Female, age 72, unknown 629.0
2849 Male, age 72, unknown 602.9
1848 Female, age 42, unknown 574.2
1890 Male, age 53, unknown 526.0
Median raphe nucleus
nTPM: 1219.9
2220 Male, age 76, midline 1219.9
Periaquaductal grey, anterior
nTPM: 993.1
1947 Male, age 18, unknown 1094.9
1795 Male, age 51, unknown 1075.4
2502 Female, age 75, unknown 809.1
Periaquaductal grey, dorsal
nTPM: 665.1
1840 Male, age 53, unknown 730.3
2850 Male, age 76, both hemispheres 720.2
1831 Male, age 72, unknown 605.1
2464 Female, age 72, unknown 604.8
Periaquaductal grey, lateral
nTPM: 593.6
2053 Male, age 18, unknown 691.0
2140 Male, age 76, both hemispheres 632.3
2272 Male, age 74, both hemispheres 457.5
Pretectal area
nTPM: 881.9
1816 Male, age 51, unknown 1383.6
2007 Male, age 72, unknown 1154.9
1944 Female, age 72, unknown 1147.9
1817 Female, age 42, unknown 998.0
2667 Female, age 75, unknown 906.9
1815 Male, age 53, unknown 902.6
2224 Female, age 72, unknown 794.9
2825 Male, age 18, unknown 762.4
2407 Male, age 75, both hemispheres 621.4
2316 Male, age 76, right hemisphere 532.7
2273 Male, age 74, both hemispheres 496.0
Red nucleus
nTPM: 702.7
2584 Male, age 75, left hemisphere 857.8
1821 Female, age 72, unknown 828.9
2588 Male, age 74, left hemisphere 813.3
2725 Female, age 75, unknown 788.3
2503 Female, age 72, unknown 718.6
2785 Male, age 18, unknown 673.4
1954 Female, age 42, unknown 663.4
2227 Male, age 72, unknown 650.9
2769 Male, age 72, unknown 635.2
1865 Male, age 51, unknown 626.1
1904 Male, age 53, unknown 616.2
2823 Male, age 76, right hemisphere 560.4
Substantia nigra
nTPM: 947.5
1916 Female, age 42, unknown 1338.2
1941 Male, age 53, unknown 1154.9
1851 Male, age 51, unknown 1020.6
1889 Female, age 72, unknown 965.3
2241 Male, age 72, unknown 950.4
2590 Female, age 75, unknown 920.5
2665 Male, age 74, both hemispheres 915.4
2583 Male, age 75, right hemisphere 795.6
2409 Female, age 72, unknown 728.2
2699 Male, age 18, unknown 685.8
Superior colliculus
nTPM: 743.1
1796 Male, age 53, unknown 1023.0
2261 Male, age 18, unknown 974.2
2087 Female, age 72, unknown 941.2
2664 Male, age 75, both hemispheres 741.1
2668 Female, age 75, unknown 728.3
2587 Male, age 74, left hemisphere 674.7
1913 Female, age 42, unknown 667.4
1839 Male, age 51, unknown 645.2
1895 Male, age 76, right hemisphere 581.0
1995 Male, age 72, unknown 455.3
Ventral tegmental area
nTPM: 936.7
2218 Male, age 76, both hemispheres 1134.8
1915 Female, age 42, unknown 1036.7
2410 Female, age 72, unknown 1020.9
2223 Female, age 72, unknown 884.2
1942 Male, age 51, unknown 797.1
2021 Male, age 53, unknown 746.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1014.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1014.1
Samples: 139

Max nTPM: 2996.0
Min nTPM: 261.0
Std nTPM: 425.0
Median nTPM: 954.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 2996.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 2573.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 2066.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 1978.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1937.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1927.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1843.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1824.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 1674.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1617.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1599.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 1596.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1594.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 1545.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1504.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1479.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 1458.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 1428.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1423.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1408.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1404.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1402.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1387.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1356.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1342.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1335.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1324.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1303.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1294.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1252.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1229.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1229.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1224.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1215.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1211.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1207.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1207.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1196.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1194.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1158.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1157.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1157.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 1151.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1137.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1130.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1119.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1118.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1116.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1109.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1103.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1095.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1095.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1093.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1078.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1075.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1063.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1061.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 1030.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1027.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1025.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 1019.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 1016.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1002.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 991.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 985.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 981.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 969.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 966.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 960.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 954.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 953.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 950.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 940.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 939.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 935.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 930.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 923.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 920.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 904.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 904.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 897.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 894.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 883.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 881.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 876.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 872.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 859.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 841.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 825.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 822.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 821.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 813.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 812.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 806.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 796.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 777.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 763.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 749.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 737.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 732.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 728.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 720.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 706.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 705.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 696.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 683.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 672.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 660.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 652.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 651.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 649.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 644.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 641.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 640.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 639.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 614.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 608.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 607.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 604.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 603.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 580.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 567.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 566.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 560.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 555.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 552.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 545.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 531.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 518.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 513.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 506.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 502.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 497.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 469.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 464.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 407.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 382.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 335.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 261.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1433.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1433.4
FF:10158-103A5 76 years, female 1433.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

723.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 723.7
Samples: 4

Max nTPM: 1049.4
Min nTPM: 279.3
Sample A Female 956.7
Sample B Female 609.3
Sample C Male 1049.4
Sample D Male 279.3
Midbrain
nTPM: 664.0
Samples: 4

Max nTPM: 874.1
Min nTPM: 493.0
Sample A Female 493.0
Sample B Female 748.5
Sample C Male 874.1
Sample D Male 540.4
Periaqueductal gray
nTPM: 649.2
Samples: 3

Max nTPM: 882.6
Min nTPM: 444.1
Sample B Female 621.0
Sample C Male 882.6
Sample D Male 444.1
Superior colliculi
nTPM: 628.0
Samples: 4

Max nTPM: 887.0
Min nTPM: 429.8
Sample A Female 710.8
Sample B Female 429.8
Sample C Male 887.0
Sample D Male 484.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1349.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 1349.7
Samples: 4

Max nTPM: 1384.9
Min nTPM: 1286.9
Sample A Male 1349.0
Sample B Male 1384.9
Sample C Female 1286.9
Sample D Female 1378.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

24.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 24.2
77465048 Antisense, RP_070129_03_A07, Mouse strain C57BL/6J (56 days, male) 24.2

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by the Knut & Alice Wallenberg Foundation.


contact@proteinatlas.org