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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:675.9 nTPM
HPA Brain:424.7 nTPM
GTEx:675.9 nTPM
FANTOM5:21.0 Scaled Tags Per Million
Mouse:339.8 nTPM
Allen mouse:17.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

424.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 394.0
2586 Male, age 75, left hemisphere 490.5
2666 Male, age 74, left hemisphere 472.9
2828 Female, age 72, unknown 421.6
1870 Female, age 42, unknown 386.3
2019 Male, age 18, unknown 378.0
1830 Male, age 51, unknown 376.4
1833 Male, age 53, unknown 373.7
2411 Female, age 72, unknown 373.5
1827 Male, age 72, unknown 358.9
2219 Male, age 76, both hemispheres 307.7
Dorsal raphe nucleus
nTPM: 374.8
2016 Female, age 72, unknown 411.5
2298 Female, age 72, unknown 383.2
2750 Male, age 76, both hemispheres 368.1
1828 Male, age 53, unknown 357.5
2047 Male, age 72, unknown 353.6
Inferior colliculus
nTPM: 352.3
2849 Male, age 72, unknown 381.3
1890 Male, age 53, unknown 355.4
1848 Female, age 42, unknown 354.6
2097 Female, age 72, unknown 317.9
Median raphe nucleus
nTPM: 369.9
2220 Male, age 76, midline 369.9
Periaquaductal grey, anterior
nTPM: 378.9
2502 Female, age 75, unknown 422.4
1795 Male, age 51, unknown 376.2
1947 Male, age 18, unknown 338.1
Periaquaductal grey, dorsal
nTPM: 364.0
2850 Male, age 76, both hemispheres 398.2
1840 Male, age 53, unknown 363.8
1831 Male, age 72, unknown 355.3
2464 Female, age 72, unknown 338.7
Periaquaductal grey, lateral
nTPM: 355.3
2272 Male, age 74, both hemispheres 368.2
2053 Male, age 18, unknown 358.7
2140 Male, age 76, both hemispheres 339.1
Pretectal area
nTPM: 355.3
1817 Female, age 42, unknown 393.8
2007 Male, age 72, unknown 381.2
2407 Male, age 75, both hemispheres 380.0
1815 Male, age 53, unknown 375.9
2825 Male, age 18, unknown 362.8
2316 Male, age 76, right hemisphere 362.6
2273 Male, age 74, both hemispheres 347.5
1816 Male, age 51, unknown 345.0
2224 Female, age 72, unknown 338.3
1944 Female, age 72, unknown 315.1
2667 Female, age 75, unknown 306.3
Red nucleus
nTPM: 394.7
2584 Male, age 75, left hemisphere 462.4
1865 Male, age 51, unknown 438.2
2503 Female, age 72, unknown 436.2
1904 Male, age 53, unknown 428.3
2769 Male, age 72, unknown 393.0
1821 Female, age 72, unknown 392.6
2227 Male, age 72, unknown 391.7
2725 Female, age 75, unknown 379.3
2785 Male, age 18, unknown 376.8
1954 Female, age 42, unknown 359.0
2823 Male, age 76, right hemisphere 342.1
2588 Male, age 74, left hemisphere 337.4
Substantia nigra
nTPM: 424.7
2699 Male, age 18, unknown 559.6
2665 Male, age 74, both hemispheres 520.1
1851 Male, age 51, unknown 489.9
2590 Female, age 75, unknown 434.8
1916 Female, age 42, unknown 428.4
2583 Male, age 75, right hemisphere 410.8
2409 Female, age 72, unknown 366.3
1941 Male, age 53, unknown 355.2
1889 Female, age 72, unknown 347.6
2241 Male, age 72, unknown 334.2
Superior colliculus
nTPM: 396.0
1995 Male, age 72, unknown 495.2
2664 Male, age 75, both hemispheres 464.1
1913 Female, age 42, unknown 458.2
2587 Male, age 74, left hemisphere 423.4
1796 Male, age 53, unknown 415.2
2668 Female, age 75, unknown 402.2
1839 Male, age 51, unknown 362.6
2261 Male, age 18, unknown 339.5
2087 Female, age 72, unknown 311.2
1895 Male, age 76, right hemisphere 288.0
Ventral tegmental area
nTPM: 414.5
1915 Female, age 42, unknown 454.5
2223 Female, age 72, unknown 452.1
2021 Male, age 53, unknown 427.9
2410 Female, age 72, unknown 402.5
2218 Male, age 76, both hemispheres 385.9
1942 Male, age 51, unknown 364.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

675.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 675.9
Samples: 139

Max nTPM: 1810.7
Min nTPM: 259.3
Std nTPM: 254.9
Median nTPM: 637.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1810.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1646.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1390.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1270.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1240.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1123.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1121.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1097.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1096.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1061.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1060.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1044.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1018.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1010.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 993.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 979.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 963.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 961.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 933.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 928.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 914.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 904.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 883.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 872.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 870.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 866.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 863.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 860.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 853.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 836.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 828.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 826.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 824.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 814.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 805.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 800.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 799.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 797.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 771.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 762.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 760.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 757.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 756.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 754.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 752.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 748.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 748.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 739.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 734.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 729.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 721.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 717.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 715.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 706.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 703.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 702.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 700.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 691.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 685.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 676.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 675.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 674.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 672.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 670.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 660.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 657.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 650.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 645.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 640.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 637.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 628.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 618.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 610.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 608.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 607.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 605.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 602.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 598.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 596.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 592.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 583.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 583.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 579.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 561.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 558.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 557.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 555.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 555.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 549.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 545.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 545.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 543.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 538.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 532.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 532.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 521.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 518.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 517.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 513.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 510.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 510.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 509.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 509.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 500.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 493.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 491.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 488.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 488.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 487.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 482.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 464.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 457.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 455.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 449.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 447.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 445.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 442.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 428.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 428.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 421.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 416.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 415.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 411.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 410.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 402.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 396.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 388.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 386.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 375.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 374.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 370.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 368.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 357.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 341.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 334.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 332.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 323.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 323.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 259.3
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

21.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 21.0
FF:10158-103A5 76 years, female 21.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

339.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 339.8
Samples: 4

Max nTPM: 379.7
Min nTPM: 305.3
Sample A Male 379.7
Sample B Male 328.2
Sample C Female 305.3
Sample D Female 346.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

17.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 17.8
100146146 Antisense, RP_110623_01_A03, Mouse strain C57BL/6J (56 days, male) 17.8

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