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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:1921.6 nTPM
HPA Brain:747.5 nTPM
GTEx:1921.6 nTPM
FANTOM5:219.8 Scaled Tags Per Million
Pig:307.2 nTPM
Mouse:775.6 nTPM
Allen mouse:10.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

747.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 660.2
2666 Male, age 74, left hemisphere 756.0
1870 Female, age 42, unknown 734.8
2828 Female, age 72, unknown 718.6
2586 Male, age 75, left hemisphere 677.3
1833 Male, age 53, unknown 662.6
1830 Male, age 51, unknown 635.7
1827 Male, age 72, unknown 625.3
2411 Female, age 72, unknown 608.3
2219 Male, age 76, both hemispheres 599.3
2019 Male, age 18, unknown 584.3
Dorsal raphe nucleus
nTPM: 673.3
2016 Female, age 72, unknown 743.1
2298 Female, age 72, unknown 716.9
1828 Male, age 53, unknown 679.7
2750 Male, age 76, both hemispheres 662.4
2047 Male, age 72, unknown 564.5
Inferior colliculus
nTPM: 664.7
2849 Male, age 72, unknown 711.2
1890 Male, age 53, unknown 683.7
2097 Female, age 72, unknown 648.7
1848 Female, age 42, unknown 615.1
Median raphe nucleus
nTPM: 639.4
2220 Male, age 76, midline 639.4
Periaquaductal grey, anterior
nTPM: 664.0
2502 Female, age 75, unknown 758.9
1795 Male, age 51, unknown 622.8
1947 Male, age 18, unknown 610.3
Periaquaductal grey, dorsal
nTPM: 676.0
2850 Male, age 76, both hemispheres 736.3
1840 Male, age 53, unknown 706.3
1831 Male, age 72, unknown 676.9
2464 Female, age 72, unknown 584.8
Periaquaductal grey, lateral
nTPM: 655.0
2140 Male, age 76, both hemispheres 696.0
2053 Male, age 18, unknown 669.1
2272 Male, age 74, both hemispheres 599.9
Pretectal area
nTPM: 637.6
2316 Male, age 76, right hemisphere 707.9
2825 Male, age 18, unknown 681.3
2224 Female, age 72, unknown 659.0
1817 Female, age 42, unknown 652.9
1815 Male, age 53, unknown 647.1
2007 Male, age 72, unknown 641.9
2667 Female, age 75, unknown 621.3
2407 Male, age 75, both hemispheres 616.7
2273 Male, age 74, both hemispheres 602.4
1944 Female, age 72, unknown 600.8
1816 Male, age 51, unknown 582.2
Red nucleus
nTPM: 701.4
2503 Female, age 72, unknown 843.9
1865 Male, age 51, unknown 776.9
1821 Female, age 72, unknown 752.7
1904 Male, age 53, unknown 751.6
2227 Male, age 72, unknown 728.1
2769 Male, age 72, unknown 720.1
2584 Male, age 75, left hemisphere 658.8
2785 Male, age 18, unknown 653.9
2725 Female, age 75, unknown 653.2
1954 Female, age 42, unknown 633.8
2588 Male, age 74, left hemisphere 632.7
2823 Male, age 76, right hemisphere 611.5
Substantia nigra
nTPM: 747.5
2699 Male, age 18, unknown 1010.7
1851 Male, age 51, unknown 903.8
2665 Male, age 74, both hemispheres 874.8
1916 Female, age 42, unknown 799.8
2409 Female, age 72, unknown 761.9
1889 Female, age 72, unknown 689.8
2241 Male, age 72, unknown 666.3
2590 Female, age 75, unknown 638.8
1941 Male, age 53, unknown 594.0
2583 Male, age 75, right hemisphere 535.4
Superior colliculus
nTPM: 703.9
2587 Male, age 74, left hemisphere 845.3
1913 Female, age 42, unknown 825.2
1995 Male, age 72, unknown 821.6
2668 Female, age 75, unknown 763.9
1796 Male, age 53, unknown 687.3
2664 Male, age 75, both hemispheres 680.2
1839 Male, age 51, unknown 654.3
2261 Male, age 18, unknown 601.4
2087 Female, age 72, unknown 589.0
1895 Male, age 76, right hemisphere 570.8
Ventral tegmental area
nTPM: 732.0
1915 Female, age 42, unknown 841.0
2223 Female, age 72, unknown 785.8
2021 Male, age 53, unknown 756.8
1942 Male, age 51, unknown 680.6
2410 Female, age 72, unknown 675.7
2218 Male, age 76, both hemispheres 652.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1921.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1921.6
Samples: 139

Max nTPM: 6036.3
Min nTPM: 663.4
Std nTPM: 756.1
Median nTPM: 1822.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 6036.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 4597.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 4566.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 4437.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 3480.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 3205.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 3067.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 3054.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 2949.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 2859.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 2839.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 2817.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 2804.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2756.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 2680.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 2612.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 2609.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 2573.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 2559.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 2555.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 2553.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 2461.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 2446.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 2421.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 2421.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 2394.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 2392.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 2382.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 2365.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 2329.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 2327.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 2308.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 2300.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 2284.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 2244.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 2209.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 2196.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 2194.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2193.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 2165.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 2159.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 2159.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 2143.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 2140.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 2140.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 2097.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 2057.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 2055.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 2054.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 2045.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 2024.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 2024.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1993.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1986.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1984.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1975.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1968.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1946.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1926.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1923.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1908.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1900.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1883.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1867.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1847.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1843.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1839.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1837.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1834.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1822.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1810.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1797.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1793.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1779.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1737.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1735.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1714.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1695.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1690.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1674.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1673.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1660.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1657.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1649.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1611.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1611.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1597.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1591.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1560.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1556.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1550.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1550.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1536.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1522.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 1516.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1502.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1499.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1494.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 1471.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1444.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1435.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1425.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1403.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1396.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 1381.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1375.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1366.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1365.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 1359.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 1350.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1339.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1294.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1290.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 1283.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1282.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 1272.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1263.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1260.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1259.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 1257.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1256.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 1233.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1197.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 1196.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1194.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 1194.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 1176.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 1165.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 1165.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 1133.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 1131.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 1114.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 1109.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1080.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 983.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 924.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 913.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 865.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 663.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

219.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 219.8
FF:10158-103A5 76 years, female 219.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

307.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 307.2
Samples: 4

Max nTPM: 381.0
Min nTPM: 250.6
Sample A Female 381.0
Sample B Female 320.3
Sample C Male 250.6
Sample D Male 276.7
Midbrain
nTPM: 286.1
Samples: 4

Max nTPM: 461.7
Min nTPM: 181.8
Sample A Female 461.7
Sample B Female 294.8
Sample C Male 205.9
Sample D Male 181.8
Periaqueductal gray
nTPM: 244.9
Samples: 3

Max nTPM: 269.3
Min nTPM: 226.1
Sample B Female 226.1
Sample C Male 269.3
Sample D Male 239.3
Superior colliculi
nTPM: 306.8
Samples: 4

Max nTPM: 364.8
Min nTPM: 247.4
Sample A Female 364.8
Sample B Female 346.9
Sample C Male 247.4
Sample D Male 268.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

775.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 775.6
Samples: 4

Max nTPM: 859.4
Min nTPM: 705.3
Sample A Male 859.4
Sample B Male 745.5
Sample C Female 705.3
Sample D Female 792.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

10.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.4
100143572 Antisense, RP_110407_01_F09, Mouse strain C57BL/6J (56 days, male) 10.4

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