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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:74.9 nTPM
HPA Brain:186.0 nTPM
GTEx:74.9 nTPM
FANTOM5:3.8 Scaled Tags Per Million
Pig:467.3 nTPM
Mouse:647.3 nTPM
Allen mouse:21.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

186.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 139.4
2019 Male, age 18, unknown 320.2
2219 Male, age 76, both hemispheres 168.6
2666 Male, age 74, left hemisphere 150.5
2586 Male, age 75, left hemisphere 132.9
2828 Female, age 72, unknown 131.0
1827 Male, age 72, unknown 114.0
1833 Male, age 53, unknown 109.1
1830 Male, age 51, unknown 103.8
2411 Female, age 72, unknown 95.1
1870 Female, age 42, unknown 69.0
Dorsal raphe nucleus
nTPM: 99.1
1828 Male, age 53, unknown 195.7
2047 Male, age 72, unknown 107.0
2750 Male, age 76, both hemispheres 69.6
2298 Female, age 72, unknown 63.8
2016 Female, age 72, unknown 59.6
Inferior colliculus
nTPM: 167.2
1890 Male, age 53, unknown 210.0
2097 Female, age 72, unknown 196.6
1848 Female, age 42, unknown 158.1
2849 Male, age 72, unknown 104.0
Median raphe nucleus
nTPM: 54.1
2220 Male, age 76, midline 54.1
Periaquaductal grey, anterior
nTPM: 64.4
2502 Female, age 75, unknown 76.1
1795 Male, age 51, unknown 60.9
1947 Male, age 18, unknown 56.3
Periaquaductal grey, dorsal
nTPM: 60.3
2464 Female, age 72, unknown 85.9
1831 Male, age 72, unknown 80.2
2850 Male, age 76, both hemispheres 40.3
1840 Male, age 53, unknown 34.9
Periaquaductal grey, lateral
nTPM: 36.2
2272 Male, age 74, both hemispheres 37.9
2140 Male, age 76, both hemispheres 35.8
2053 Male, age 18, unknown 35.0
Pretectal area
nTPM: 186.0
1817 Female, age 42, unknown 428.0
1944 Female, age 72, unknown 338.7
1816 Male, age 51, unknown 331.0
2007 Male, age 72, unknown 327.9
1815 Male, age 53, unknown 182.7
2667 Female, age 75, unknown 178.7
2407 Male, age 75, both hemispheres 69.3
2316 Male, age 76, right hemisphere 67.2
2273 Male, age 74, both hemispheres 45.8
2825 Male, age 18, unknown 42.5
2224 Female, age 72, unknown 33.6
Red nucleus
nTPM: 148.0
2785 Male, age 18, unknown 329.6
2823 Male, age 76, right hemisphere 174.0
2588 Male, age 74, left hemisphere 154.4
1821 Female, age 72, unknown 151.3
2503 Female, age 72, unknown 140.4
2584 Male, age 75, left hemisphere 138.0
1954 Female, age 42, unknown 137.4
2769 Male, age 72, unknown 132.4
1865 Male, age 51, unknown 131.4
2227 Male, age 72, unknown 129.1
1904 Male, age 53, unknown 85.7
2725 Female, age 75, unknown 72.5
Substantia nigra
nTPM: 128.8
1889 Female, age 72, unknown 305.5
1941 Male, age 53, unknown 212.4
2665 Male, age 74, both hemispheres 171.6
1916 Female, age 42, unknown 136.3
1851 Male, age 51, unknown 98.7
2583 Male, age 75, right hemisphere 85.3
2590 Female, age 75, unknown 78.2
2699 Male, age 18, unknown 77.8
2409 Female, age 72, unknown 68.9
2241 Male, age 72, unknown 53.2
Superior colliculus
nTPM: 143.9
2087 Female, age 72, unknown 301.4
2668 Female, age 75, unknown 216.9
1895 Male, age 76, right hemisphere 179.8
1995 Male, age 72, unknown 122.9
1913 Female, age 42, unknown 121.6
2261 Male, age 18, unknown 111.3
2664 Male, age 75, both hemispheres 109.4
1839 Male, age 51, unknown 104.8
1796 Male, age 53, unknown 95.5
2587 Male, age 74, left hemisphere 75.2
Ventral tegmental area
nTPM: 84.1
2410 Female, age 72, unknown 111.4
2218 Male, age 76, both hemispheres 102.3
1915 Female, age 42, unknown 98.7
2223 Female, age 72, unknown 89.7
1942 Male, age 51, unknown 60.1
2021 Male, age 53, unknown 42.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

74.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 74.9
Samples: 139

Max nTPM: 526.5
Min nTPM: 6.3
Std nTPM: 69.5
Median nTPM: 51.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 526.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 283.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 262.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 238.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 224.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 191.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 183.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 183.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 179.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 177.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 172.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 170.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 164.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 163.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 160.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 157.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 157.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 155.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 143.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 143.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 142.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 140.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 139.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 127.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 127.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 125.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 125.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 124.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 120.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 120.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 119.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 116.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 114.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 106.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 98.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 97.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 96.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 94.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 92.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 91.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 90.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 89.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 88.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 87.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 86.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 85.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 84.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 84.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 83.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 82.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 82.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 80.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 80.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 78.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 76.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 74.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 70.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 70.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 67.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 64.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 64.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 62.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 59.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 58.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 57.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 56.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 55.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 53.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 52.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 51.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 50.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 50.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 48.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 47.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 46.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 45.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 44.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 44.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 44.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 42.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 41.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 40.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 40.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 37.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 37.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 36.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 36.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 36.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 35.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 35.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 35.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 34.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 33.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 32.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 31.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 30.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 30.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 29.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 27.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 27.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 27.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 26.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 26.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 26.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 26.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 25.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 25.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 24.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 23.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 23.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 23.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 22.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 22.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 21.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 21.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 21.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 20.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 19.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 18.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 18.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 18.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 17.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 17.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 17.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 17.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 16.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 15.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 13.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 13.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 12.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 12.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 12.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 11.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 11.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 10.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 9.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 9.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 6.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 6.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

3.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 3.8
FF:10158-103A5 76 years, female 3.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

467.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 108.6
Samples: 4

Max nTPM: 153.9
Min nTPM: 62.0
Sample A Female 153.9
Sample B Female 62.0
Sample C Male 107.5
Sample D Male 110.8
Midbrain
nTPM: 253.9
Samples: 4

Max nTPM: 544.9
Min nTPM: 55.2
Sample A Female 55.2
Sample B Female 75.4
Sample C Male 544.9
Sample D Male 340.0
Periaqueductal gray
nTPM: 75.4
Samples: 3

Max nTPM: 91.4
Min nTPM: 59.5
Sample B Female 91.4
Sample C Male 75.4
Sample D Male 59.5
Superior colliculi
nTPM: 467.3
Samples: 4

Max nTPM: 800.9
Min nTPM: 233.8
Sample A Female 448.3
Sample B Female 233.8
Sample C Male 800.9
Sample D Male 386.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

647.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 647.3
Samples: 4

Max nTPM: 669.3
Min nTPM: 633.0
Sample A Male 643.9
Sample B Male 633.0
Sample C Female 669.3
Sample D Female 642.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

21.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 21.4
68193003 Antisense, RP_040922_01_D06, Mouse strain C57BL/6J (56 days, male) 21.4
67752308 Antisense, RP_040922_01_D06, Mouse strain C57BL/6J (56 days, male) 20.3

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