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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:1575.0 nTPM
HPA Brain:316.8 nTPM
GTEx:1575.0 nTPM
FANTOM5:339.1 Scaled Tags Per Million
Pig:514.7 nTPM
Mouse:873.3 nTPM
Allen mouse:4.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

316.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 243.8
2411 Female, age 72, unknown 301.9
1870 Female, age 42, unknown 268.3
2219 Male, age 76, both hemispheres 259.9
2019 Male, age 18, unknown 257.1
2586 Male, age 75, left hemisphere 252.1
2828 Female, age 72, unknown 243.1
1827 Male, age 72, unknown 235.2
2666 Male, age 74, left hemisphere 209.0
1833 Male, age 53, unknown 208.5
1830 Male, age 51, unknown 203.1
Dorsal raphe nucleus
nTPM: 258.7
2298 Female, age 72, unknown 356.6
2750 Male, age 76, both hemispheres 263.8
2016 Female, age 72, unknown 253.4
1828 Male, age 53, unknown 217.0
2047 Male, age 72, unknown 202.8
Inferior colliculus
nTPM: 238.2
2097 Female, age 72, unknown 298.8
1890 Male, age 53, unknown 272.1
1848 Female, age 42, unknown 210.5
2849 Male, age 72, unknown 171.5
Median raphe nucleus
nTPM: 226.3
2220 Male, age 76, midline 226.3
Periaquaductal grey, anterior
nTPM: 310.3
2502 Female, age 75, unknown 384.5
1795 Male, age 51, unknown 284.7
1947 Male, age 18, unknown 261.8
Periaquaductal grey, dorsal
nTPM: 228.7
1840 Male, age 53, unknown 260.9
2464 Female, age 72, unknown 253.9
1831 Male, age 72, unknown 225.4
2850 Male, age 76, both hemispheres 174.5
Periaquaductal grey, lateral
nTPM: 207.2
2053 Male, age 18, unknown 233.6
2140 Male, age 76, both hemispheres 208.6
2272 Male, age 74, both hemispheres 179.5
Pretectal area
nTPM: 248.4
2007 Male, age 72, unknown 294.2
1816 Male, age 51, unknown 293.8
2224 Female, age 72, unknown 288.7
2316 Male, age 76, right hemisphere 270.8
1817 Female, age 42, unknown 266.3
1815 Male, age 53, unknown 248.8
2667 Female, age 75, unknown 236.1
1944 Female, age 72, unknown 235.3
2825 Male, age 18, unknown 218.7
2273 Male, age 74, both hemispheres 207.4
2407 Male, age 75, both hemispheres 172.9
Red nucleus
nTPM: 275.1
2503 Female, age 72, unknown 359.5
1821 Female, age 72, unknown 320.9
1904 Male, age 53, unknown 302.0
2227 Male, age 72, unknown 300.1
1865 Male, age 51, unknown 285.9
2769 Male, age 72, unknown 284.4
2785 Male, age 18, unknown 272.0
2725 Female, age 75, unknown 266.4
2588 Male, age 74, left hemisphere 248.6
1954 Female, age 42, unknown 233.7
2584 Male, age 75, left hemisphere 225.6
2823 Male, age 76, right hemisphere 202.5
Substantia nigra
nTPM: 316.8
2409 Female, age 72, unknown 532.1
1851 Male, age 51, unknown 435.3
2241 Male, age 72, unknown 348.6
1916 Female, age 42, unknown 333.2
2699 Male, age 18, unknown 298.6
2665 Male, age 74, both hemispheres 296.6
1889 Female, age 72, unknown 263.9
2590 Female, age 75, unknown 233.5
1941 Male, age 53, unknown 230.6
2583 Male, age 75, right hemisphere 196.0
Superior colliculus
nTPM: 260.3
1796 Male, age 53, unknown 316.1
1913 Female, age 42, unknown 295.1
2261 Male, age 18, unknown 285.0
1995 Male, age 72, unknown 283.4
2668 Female, age 75, unknown 282.4
2087 Female, age 72, unknown 261.6
2587 Male, age 74, left hemisphere 254.7
1895 Male, age 76, right hemisphere 233.0
1839 Male, age 51, unknown 207.6
2664 Male, age 75, both hemispheres 184.6
Ventral tegmental area
nTPM: 283.8
1915 Female, age 42, unknown 355.7
2223 Female, age 72, unknown 314.4
2410 Female, age 72, unknown 304.6
2021 Male, age 53, unknown 267.7
1942 Male, age 51, unknown 246.0
2218 Male, age 76, both hemispheres 214.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1575.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1575.0
Samples: 139

Max nTPM: 5435.3
Min nTPM: 555.1
Std nTPM: 736.1
Median nTPM: 1390.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 5435.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 4937.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 4072.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 3790.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 3049.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 2996.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 2907.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 2816.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 2675.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 2651.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 2613.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 2582.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 2512.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 2436.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 2392.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 2389.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 2198.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 2152.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 2148.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 2109.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 2086.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 2021.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1977.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1965.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1965.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1965.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1955.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1949.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1934.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1903.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1890.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1890.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1886.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1847.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1845.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1837.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1811.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1771.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1765.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1756.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1728.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1726.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1722.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1712.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1712.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1701.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1681.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1681.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1651.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 1617.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1575.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1571.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1565.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1550.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1542.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1527.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1522.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1511.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1510.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1498.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1498.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1488.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1483.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1481.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1474.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1443.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1427.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1427.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1407.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1390.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1374.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1371.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1370.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1369.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1363.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1355.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1349.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1316.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1308.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1307.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1303.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1303.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1291.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1282.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1272.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1271.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1271.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1247.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1244.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1244.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1240.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1230.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 1227.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1226.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 1224.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1223.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1223.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 1213.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1200.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1185.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 1153.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 1149.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1140.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1135.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1109.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1081.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 1080.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1073.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1068.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1057.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1053.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1049.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1045.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1035.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1029.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1015.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1011.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 971.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 971.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 962.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 946.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 936.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 935.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 923.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 910.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 901.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 883.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 864.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 836.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 828.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 823.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 823.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 788.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 782.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 776.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 759.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 759.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 562.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 555.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

339.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 339.1
FF:10158-103A5 76 years, female 339.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

514.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 514.7
Samples: 4

Max nTPM: 754.2
Min nTPM: 384.9
Sample A Female 754.2
Sample B Female 523.2
Sample C Male 396.4
Sample D Male 384.9
Midbrain
nTPM: 499.7
Samples: 4

Max nTPM: 763.0
Min nTPM: 319.0
Sample A Female 763.0
Sample B Female 545.0
Sample C Male 371.9
Sample D Male 319.0
Periaqueductal gray
nTPM: 375.3
Samples: 3

Max nTPM: 396.1
Min nTPM: 344.5
Sample B Female 385.3
Sample C Male 396.1
Sample D Male 344.5
Superior colliculi
nTPM: 500.9
Samples: 4

Max nTPM: 656.0
Min nTPM: 395.9
Sample A Female 656.0
Sample B Female 518.5
Sample C Male 433.2
Sample D Male 395.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

873.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 873.4
Samples: 4

Max nTPM: 1129.1
Min nTPM: 679.2
Sample A Male 1129.1
Sample B Male 806.3
Sample C Female 679.2
Sample D Female 878.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.7
74425523 Antisense, RP_051214_02_E09, Mouse strain C57BL/6J (56 days, male) 7.1
68545854 Antisense, RP_050120_01_F03, Mouse strain C57BL/6J (56 days, male) 2.3

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